scholarly journals Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: The Rotterdam Study

Neurology ◽  
1994 ◽  
Vol 44 (7) ◽  
pp. 1246-1246 ◽  
Author(s):  
M.M.B. Breteler ◽  
J. C. van Swieten ◽  
M. L. Bots ◽  
D. E. Grobbee ◽  
J. J. Claus ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Function ◽  
White Matter ◽  
White Matter Lesions ◽  
Population Based ◽  
Cerebral White Matter ◽  
Vascular Risk ◽  
Rotterdam Study ◽  
Population Based Study ◽  
Cerebral White Matter Lesions

scholarly journals Vascular risk factors, atherosclerosis, cerebral white matter lesions and cerebral perfusion in a population-based study

1996 ◽  
Vol 23 (6) ◽  
pp. 675-682 ◽  
Author(s):  
J. J. Claus ◽  
M. M. B. Breteler ◽  
D. Hasan ◽  
E. P. Krenning ◽  
M. L. Bots ◽  
...  
Keyword(s):  
Risk Factors ◽  
White Matter ◽  
Cerebral Perfusion ◽  
White Matter Lesions ◽  
Population Based ◽  
Vascular Risk Factors ◽  
Cerebral White Matter ◽  
Vascular Risk ◽  
Population Based Study ◽  
Cerebral White Matter Lesions

scholarly journals Association of cerebral white matter lesions with cognitive function and mood in J apanese elderly people: a population‐based study

2015 ◽  
Vol 5 (3) ◽  
Author(s):  
Mika Yamawaki ◽  
Kenji Wada‐Isoe ◽  
Mikie Yamamoto ◽  
Satoko Nakashita ◽  
Yusuke Uemura ◽  
...  
Keyword(s):  
Cognitive Function ◽  
White Matter ◽  
Elderly People ◽  
White Matter Lesions ◽  
Population Based ◽  
Cerebral White Matter ◽  
Population Based Study ◽  
Cerebral White Matter Lesions

Silent Cerebral White Matter Lesions and Their Relationship With Vascular Risk Factors in Middle-Aged Predialysis Patients With CKD

2006 ◽  
Vol 47 (2) ◽  
pp. 241-250 ◽  
Author(s):  
Alberto Martinez-Vea ◽  
Esther Salvadó ◽  
Alfredo Bardají ◽  
Cristina Gutierrez ◽  
Ana Ramos ◽  
...  
Keyword(s):  
Risk Factors ◽  
White Matter ◽  
White Matter Lesions ◽  
Vascular Risk Factors ◽  
Cerebral White Matter ◽  
Vascular Risk ◽  
Middle Aged ◽  
Cerebral White Matter Lesions

A population-based study of the association between cerebral white matter lesions and cognitive functions

2000 ◽  
Vol 21 ◽  
pp. 247
Author(s):  
Carole Dufouil ◽  
Christophe Tzourio ◽  
Veronique Besancon ◽  
Claude Levy ◽  
Axel de Kersaint Gilly ◽  
...  
Keyword(s):  
White Matter ◽  
Cognitive Functions ◽  
White Matter Lesions ◽  
Population Based ◽  
Cerebral White Matter ◽  
Population Based Study ◽  
Cerebral White Matter Lesions

Cerebral White Matter Lesions have Low Impact on Cognitive Function in a Large Elderly Memory Clinic Population

2018 ◽  
Vol 63 (3) ◽  
pp. 1129-1139 ◽  
Author(s):  
Jules J. Claus ◽  
Mirthe Coenen ◽  
Salka S. Staekenborg ◽  
Jacqueline Schuur ◽  
Caroline E.M. Tielkes ◽  
...  
Keyword(s):  
Cognitive Function ◽  
White Matter ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Memory Clinic ◽  
Cerebral White Matter Lesions ◽  
Clinic Population

P2-302: VASCULAR RISK FACTORS, APOE GENE ABNORMALITIES IN WHITE-MATTER MICROSTRUCTURE, AND COGNITIVE DECLINE IN OLD AGE: A POPULATION-BASED STUDY

2014 ◽  
Vol 10 ◽  
pp. P588-P588
Author(s):  
Chengxuan Qiu ◽  
Rui Wang ◽  
Laura Fratiglioni ◽  
Erika Jonsson Laukka ◽  
Martin Lövden ◽  
...  
Keyword(s):  
Risk Factors ◽  
White Matter ◽  
Cognitive Decline ◽  
Old Age ◽  
Population Based ◽  
Vascular Risk Factors ◽  
Apoe Gene ◽  
Vascular Risk ◽  
Population Based Study ◽  
White Matter Microstructure

scholarly journals The Association between Cerebral White Matter Lesions and Plasma Omega-3 to Omega-6 Polyunsaturated Fatty Acids Ratio to Cognitive Impairment Development

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Michihiro Suwa ◽  
Shigeru Yamaguchi ◽  
Tsuyoshi Komori ◽  
Sachiko Kajimoto ◽  
Masaya Kino
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
White Matter ◽  
White Matter Lesions ◽  
White Matter Hyperintensity ◽  
Cerebral White Matter ◽  
Omega 3 ◽  
Arachidonic Acids ◽  
Low Serum

Objective. Cerebral white matter hyperintensity (WMH) with magnetic resonance imaging (MRI) has a potential for predicting cognitive impairment. Serum polyunsaturated fatty acid (PUFA) levels are important for evaluating the extent of atherosclerosis. We investigated whether abnormal PUFA levels affected WMH grading and cognitive function in patients without significant cognitive impairment.Methods. Atherosclerotic risk factors, the internal carotid artery (ICA) plaque, and serum ratios of eicosapentaenoic to arachidonic acids (EPA/AA) and docosahexaenoic to arachidonic acids (DHA/AA) were assessed in 286 patients. The relationship among these risk factors, WMH, and cognitive function was evaluated using WMH grading and the Mini-Mental State Examination (MMSE).Results. The development of WMH was associated with aging, hypertension, ICA plaques, and a low serum EPA/AA ratio (<0.38, obtained as the median value) but was not related to dyslipidemia, diabetes, smoking, and a low serum DHA/AA ratio (<0.84, obtained as the median value). In addition, the MMSE score deteriorated slightly with the progression of WMH (29.7 ± 1.0 compared to 28.4 ± 2.1,P<0.0001).Conclusions. The progression of WMH was associated with a low serum EPA/AA ratio and accompanied minimal deterioration in cognitive function. Sufficient omega-3 PUFA intake may be effective in preventing the development of cognitive impairment.

scholarly journals Cerebral white matter lesions and atherosclerosis in the Rotterdam Study

The Lancet ◽  
1993 ◽  
Vol 341 (8855) ◽  
pp. 1232-1237 ◽  
Author(s):  
M.L Bots ◽  
M.M.B Breteler ◽  
A Hofman ◽  
D.E Grobbee ◽  
J.C van Swieten ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Rotterdam Study ◽  
Cerebral White Matter Lesions
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