scholarly journals Studies on Absorption of Drugs. VIII. Physicochemical Factors affecting the Absorption of Sulfonamides from the Rat Small Intestine

1973 ◽  
Vol 21 (10) ◽  
pp. 2309-2322 ◽  
Author(s):  
TAKASHI MORISHITA ◽  
MASARU YAMAZAKI ◽  
NOBORU YATA ◽  
AKIRA KAMADA
2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  

2008 ◽  
Vol 29 (S 1) ◽  
Author(s):  
K Nieber ◽  
S Michael ◽  
K Grötzinger ◽  
JW Rauwald ◽  
O Kelber

Diabetes ◽  
1993 ◽  
Vol 42 (8) ◽  
pp. 1126-1132 ◽  
Author(s):  
K. L. Madsen ◽  
V. M. Porter ◽  
R. N. Fedorak

1989 ◽  
Vol 21 (2) ◽  
pp. 147-150 ◽  
Author(s):  
D. W. Hawker ◽  
D. W. Connell

The influence of some important biological and physicochemical factors on the bioconcentration of hydrophobic organic chemicals is outlined. For non-ionizable, persistent compounds the bioconcentration factor can be related to a compound's octanol/water partition coefficient, aqueous solubility and molecular weight, while the lipid content of an organism also affects the bioconcentration potential of these compounds. The effect of ionization and biodegradation of organic chemicals on bioconcentration is also discussed.


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