scholarly journals An isolated vascularly perfused stomach for studying drug distribution, metabolism and action in the stomach: Acid secretion in response to secretagogues.

1983 ◽  
Vol 31 (10) ◽  
pp. 3644-3648
Author(s):  
RYOHEI HORI ◽  
SEIGO IWAKAWA ◽  
JUNKO KAGIMOTO ◽  
SETSUKO OKURA ◽  
KATSUHIKO OKUMURA
Keyword(s):  
Acid Secretion ◽  
Drug Distribution ◽  
Stomach Acid ◽  
Isolated Vascularly Perfused Stomach

Pentagastrin, a stimulator of stomach acid secretion

1976 ◽  
Vol 10 (11) ◽  
pp. 1572-1573
Author(s):  
A. A. Kimenis ◽  
Z. A. Atare ◽  
G. I. Chipens
Keyword(s):  
Acid Secretion ◽  
Stomach Acid

Stomach acid secretion in submissive and aggressive rats.

1986 ◽  
Vol 100 (3) ◽  
pp. 381-389 ◽  
Author(s):  
William P. Paré ◽  
George P. Vincent
Keyword(s):  
Acid Secretion ◽  
Stomach Acid

Cytopathology of Cardiac Tissue from Daunomycin-Treated Mice

1971 ◽  
Vol 29 ◽  
pp. 550-551
Author(s):  
Robert H. Liss ◽  
Frances A. Cotton
Keyword(s):  
Cardiac Tissue ◽  
Cardiac Toxicity ◽  
Drug Distribution ◽  
Personal Communication ◽  
Intravenous Dose ◽  
Single Intravenous Dose ◽  
Physiologic Saline ◽  
Histopathologic Changes ◽  
Distribution Studies ◽  
Lung And Kidney

Daunomycin, an antibiotic used in the clinical management of acute leukemia, produces a delayed, lethal cardiac toxicity. The lethality is dose and schedule dependent; histopathologic changes induced by the drug have been described in heart, lung, and kidney from hamsters in both single and multiple dose studies. Mice given a single intravenous dose of daunomycin (10 mg/kg) die 6-7 days later. Drug distribution studies indicate that the rodents excrete most of a single dose of the drug as daunomycin and metabolite within 48 hours after dosage (M. A. Asbell, personal communication).Myocardium from the ventricles of 6 moribund BDF1 mice which had received a single intravenous dose of daunomycin (10 mg/kg), and from controls dosed with physiologic saline, was fixed in glutaraldehyde and prepared for electron microscopy.

Expression of NKCC1 and NKCC2 in gastric mucosa and their possible role in acid secretion

2010 ◽  
Vol 34 (8) ◽  
pp. S2-S2
Author(s):  
Tuo Ji ◽  
Hong Xue ◽  
Zhangfeng Dou ◽  
Yue Zhang ◽  
Jinxia Zhu
Keyword(s):  
Gastric Mucosa ◽  
Acid Secretion

The Mechanism by Which Alcohol Stimulates Acid Secretion

1960 ◽  
Vol 39 (1) ◽  
pp. 41-47 ◽  
Author(s):  
W.T. Irvine ◽  
D.B. Watkin ◽  
E.J. Williams
Keyword(s):  
Acid Secretion
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