stomach acid
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2021 ◽  
Vol 2 (2) ◽  
pp. 59-64
Author(s):  
Alexendru Retiu ◽  
Tenase Budescu ◽  
Iaoani Menae

The purpose of this study was to determine the effectiveness of aloe vera juice against stomach acid. Aloe vera also contains key elements such as resin, aloin, tannins, aloin-emodin, polysaccharides, 19 amino acids, 12 vitamins and 20 minerals that are important for health. Aloe vera is a natural ingredient that is good for detoxifying heavy metals in the body, and is able to maximize the performance of the digestive system. consuming aloe vera juice in a certain dose, is very effective for healing wounds in the stomach, as well as being a natural remedy for stomach ulcers which is quite effective. Aloe vera has the ability to stimulate the release of pepsin, which is an enzyme in the stomach that works to support the digestive system


Author(s):  
Niesa Surya Dianti Putri ◽  
Alvira Rizka Utami ◽  
Amelia Novita ◽  
Cindi Maduri ◽  
Munaya Fauziah

Gastritis is an inflammatory process or health problem caused by irritation and infection of the gastric mucosa and submucosa. Gastritis can attack all levels of society from all levels of age and gender. Diet is to provide an overview of the way or behavior taken by a person or group of people in choosing and using the food consumed every day which includes the regularity of eating frequency, meal portions, and the type of food and drink consumed based on social and cultural factors in which they live. According to Riskesdas 2013, the incidence of gastritis in several regions of Indonesia is quite high with a prevalence of 274,369 cases from 238,452,952 inhabitants, it was found that in the city of Surabaya the incidence of gastritis was 31.2%, Denpasar 46% while in Central Java the incidence of gastritis is quite high at 79.6%. Gastritis usually occurs due to irregular eating frequency so that the stomach becomes sensitive when stomach acid increases. It is better for people who have a history of gastric disease not to eat acidic and spicy foods because they can cause gastritis to recur.


2021 ◽  
Vol 4 (1) ◽  
pp. 14-18
Author(s):  
Desi Yusnita ◽  
Visensius Krisdianilo

Acute diarrhea due to infection can be caused by a bacterial, viral or parasitic infection. One of the bacteria that causes diarrhea is Vibrio cholerae and usually the diarrhea caused is called cholera diarrhea. Cholera diarrhea is caused by enterotoxins produced by V. cholerae bacteria and forms colonies inside the small intestine. Symptoms include vomiting, defecation such as large amounts of rice water resulting in dehydration, electrolyte loss and increased blood acidity. In severe cases, the sufferer continuously defecates accompanied by vomiting, so that the sufferer will lose fluids and electrolytes quickly from the gastrointestinal tract. This leads to a rationing of metabolic acidity and when left untreated can lead to death. V. cholerae bacteria are not invasive, do not enter the bloodstream but remain in the intestinal tract. At the time of infection through contaminated food and beverages ingested, then after passing through the stomach acid defense V. cholerae produces two virulence factors that cause cholera, namely coregulated pilus toxin (TCP) and cholera toxin (CT). The existence of specific enterotoxin cholera only found in V. cholerae pathogens can be targeted in laboratory tests for the diagnosis of pathogenic V. cholerae bacteria using biomolecular techniques such as polymerase chain reaction (PCR) methods. From the results of the examination of drinking water samples at the drinking water depot around the bottom of the pakam, obtained the results of the PCR examination confirmed by electrophorensis is 302 bp, which means that in the sample there are bacteria that are identic with Vibrio cholera.


Author(s):  
Grazia Mazzeo ◽  
Luigi Aronne ◽  
Domenica Francesca Mariniello ◽  
Valentino Allocca ◽  
Maria Ilaria Palma ◽  
...  

Identification of risk factors for severe outcome of Sars-Cov-2 infection is an important issue in COVID-19 management. Much attention has been focused on comorbidities as well as drugs taken by patients. Usage of proton pump inhibitors (PPIs) appears to potentially influence disease course. These drugs are known to reduce stomach acid and also modulate the immune system. Their use, prior to and during COVID-19 infection, seems to predispose to the development of more severe pneumonia and therefore to a greater risk of mortality. Instead, the use of Histamine receptor 2 antagonists (H2RAs) seems to be associated with a better outcome in patients with COVID-19, in terms of symptoms, risk of intubation and death. As PPIs are essential for treatment of many disorders, usage of these drugs should be balanced considering the benefits and risk ratio, in order to guarantee their correct use for the necessary time. It remains to be clarified whether the detrimental effects, in terms of COVID19 severe outcome, are due to PPIs or to the underlying disease for which they are administered. New controlled-randomized trials are required to better understand their impact in SARS-COV-2 infections. *Vanvitelli/Monaldi COVID Group: Adriano Cristinziano, Carolina Delle Donne, Cecilia Calabrese, Fabio Perrotta, Filippo Scialò, Francesco Lassandro, Gennaro Mazzarella, Giorgio Paoli, Leonardo De Luca, Maria Galdo, Miriam Buonincontro, Roberta Cianci, Rosalba Donizzetti, Stefano Sanduzzi Zamparelli, Tullio Valente, Vito D’Agnano, Vittorio Bisogni


Author(s):  
Subha K Nampoothiri ◽  
A Shahul Hameed

Peptic-ulcer-disease is the ulceration of gasrtric or duodenal mucosa due to the digestive action of pepsin and stomach acid. Gastritis, gastric ulcer and duodenal ulcer are included under this. It can be correlated with the condition Parinamasoola mentioned in Ayurveda. Avipathichoornam is a famous Ayurvedic formulation, mentioned in the texts Ashtanga Hridaya and Sahasrayoga. Avipathi choorna exerts its effect in Peptic ulcer disease probably through Deepana, Pachana and Saraka actions by virtue of the pharmacological properties of the ingredients with which the vitiated Pitta can get normalized. It can be deducted that Avipathi choorna probably neutralize the excess acid secretion in the gastrointestinal tract and maintain a healthy pH. The formulation also probably acts by the anti inflammatory property of most of the ingredients which can help pacify the inflamed tissue layer of the gut. The aim of this paper is to demonstrate mode of action of Avipathi choorna in peptic ulcer disease by critically analyzing the pharmacological properties as well as chemical constituent of the ingredients.


Author(s):  
Tanvir Hussain ◽  
Aishan Patil ◽  
Amy Copperthwaite ◽  
Ronan Fahy ◽  
Emma Keane

<p class="abstract"><strong>Background:</strong> Globus pharyngeus, also known as globus sensation, can be defined as the sensation of a lump or foreign body in the absence of a mass on examination. The disorder is frequently linked to catarrh, hoarseness, chronic cough and persistent throat clearing. Globus pharyngeus accounts for 4 percent of ENT (ear, nose and throat) referrals. The exact cause of globus pharyngeus is unknown. The presence of lingual tonsil, cricopharyngeal spasm, hiatus hernia, cervical osteophytosis, sinusitis, gastro-oesophageal reflux, goiter post-nasal drip and anxiety have all been shown as associations in the literature. Digestive enzymes and regurgitation of stomach acid are thought to cause persistent inflammation, for example, of the laryngopharynx, which causes symptoms. Reflux has been depicted in 23-68 percent of patients with globus sensation. Notably, some studies claim that asymptomatic control patients have a similar rate.</p><p class="abstract"><strong>Methods:</strong> We presented our audit study of 50 subsets of patients. It was considered that gastro-oesophageal reflux was the reason; however, it cannot explain all the potential causes.</p><p class="abstract"><strong>Results:</strong> Barium swallow was found to be a very key diagnostic tool in this group of patients.</p><p class="abstract"><strong>Conclusions:</strong> Panendoscopy in globus sensation in the throat, looking through the possible causes of globus sensation, current trends and diagnosis as well as methods of treatment.</p>


2021 ◽  
Vol 5 (4) ◽  
pp. 108-111
Author(s):  
Wei Cui ◽  
Li Liu ◽  
Xiaoquan Du ◽  
Chunxia Ma ◽  
Xuzhao Wang

Acid regurgitation is a common symptom in digestive system diseases which is mainly caused by emotions, diet, and other factors. It is related to gastroesophageal reflux disease, chronic gastritis, and other diseases in Western medicine. According to modern medical research, acid reflux is related to Helicobacter pylori (HP) infection, weak effect of anti-reflux barrier, decreased clearance of esophageal acid, dysfunction of esophageal mucosal barrier, strong stimulation of reflux on esophageal mucosal wall, and other factors [1]. It can be divided into four types which are heat, cold, food stagnation, and yin deficiency. It is often accompanied by vomiting, heartburn, stomachache, and other symptoms. Clinically, it is a mixture of cold and heat, as well as excess and deficiency. Professor Du’s self-made method of “first soothing, second reducing, and third harmonizing” (soothing liver and stomach, relieving stomach qi, and neutralizing stomach acid) is used to treat both, symptoms and the root causes. The commonly used prescriptions are left-running metal pill, cuttlefish bone and fritillaria powder, calcined ark shell, oyster shell, etc.


2021 ◽  
Vol 28 ◽  
Author(s):  
Maryam Shamseddini lori ◽  
Mandana Ohadi ◽  
Mohammad Amin Raeisi Estabragh ◽  
Sepehr Afsharipour ◽  
Ibrahim M Banat ◽  
...  

: There are many proteins and enzymes in the human body, and their dysfunction can lead to disease. The use of proteins as a drug is common in various diseases such as diabetes. Proteins are hydrophilic molecules whose spatial structure is critical to their correct function. There are different ways to the administration of proteins. Protein structures are degraded by gastric acid and enzymes in the gastrointestinal tract and have a slight ability to permeation from the gastrointestinal epithelium due to their large hydrophilic nature. Therefore, their oral use has limitations. Since the oral use of drugs is one of the best and easiest routes for patients, many studies have been done to increase the stability, penetration and ultimately increase the bioavailability of proteins through oral administration. One of the studied strategies for oral delivery of protein is the use of pH-sensitive polymer-based carriers. These carriers use different pH-sensitive polymers such as eudragit®, chitosan, dextran, and alginate. The use of pH-sensitive polymer-based carriers by protecting the protein from stomach acid (low pH) and degrading enzymes, increasing permeability, and maintaining the spatial structure of the protein leads to increased bioavailability. In this review, we focus on the various polymers used to prepare pH-sensitive polymer-based carriers for the oral delivery of proteins.


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