scholarly journals Selective protection of the primary hydroxyl groups of oxetanocin A and conformational analysis of O-protected oxetanocin A.

1995 ◽  
Vol 43 (5) ◽  
pp. 884-886 ◽  
Author(s):  
Nobuya KATAGIRI ◽  
Masashi MAKINO ◽  
Chikara KANEKO
Keyword(s):  
Conformational Analysis ◽  
Hydroxyl Groups ◽  
Selective Protection ◽  
Primary Hydroxyl

scholarly journals A Synthetic Strategy for Conjugation of Paromomycin to Cell-Penetrating Tat(48-60) for Delivery and Visualization into Leishmania Parasites

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Sira Defaus ◽  
Maria Gallo ◽  
María A. Abengózar ◽  
Luis Rivas ◽  
David Andreu
Keyword(s):  
Aminoglycoside Antibiotic ◽  
Cell Penetrating Peptides ◽  
Hydroxyl Groups ◽  
Selective Protection ◽  
Synthetic Strategy ◽  
Cell Penetrating ◽  
Successful Approach ◽  
Leishmania Parasites

A successful approach to deliver paromomycin, a poorly absorbed aminoglycoside antibiotic, to parasite cells is reported, based on selective protection of amino and hydroxyl groups followed by conjugation to a fluorolabeled, PEG-functionalized cell-penetrating Tat(48-60) peptide. The resulting construct is efficiently internalized into Leishmania cells, evidencing the fitness of cell-penetrating peptides as vectors for efficiently transporting low-bioavailability drugs into cells.

scholarly journals An efficient partial synthesis of 4′-O-methylquercetin via regioselective protection and alkylation of quercetin

2009 ◽  
Vol 5 ◽  
Author(s):  
Nian-Guang Li ◽  
Zhi-Hao Shi ◽  
Yu-Ping Tang ◽  
Jian-Ping Yang ◽  
Jin-Ao Duan
Keyword(s):  
Diphenyl Ether ◽  
Hydroxyl Groups ◽  
Partial Synthesis ◽  
Selective Protection ◽  
Catechol Group

An efficient partial 5-step synthesis of 4′-O-methylquercetin from quercetin in 63% yield is reported. This strategy relies on the selective protection of the catechol group with dichlorodiphenylmethane in diphenyl ether as solvent and on the selective protection of the hydroxyl groups at positions 3 and 7 with chloromethyl ether.

Synthesis and characterization of α-butyl-ω-{3-[(2,2- dihydroxymethyl)-propionyloxy]}propyl polydimethyl siloxane

e-Polymers ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Meng Zhang ◽  
Yuanjuan Wu ◽  
Qingsi Zhang ◽  
Tianduo Li
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Synthesis And Characterization ◽  
Hydroxyl Groups ◽  
Single Chain ◽  
Polydimethyl Siloxane ◽  
Primary Hydroxyl ◽  
Anionic Ring

AbstractA novel polydimethylsiloxane containing two primary hydroxyl groups at one single chain end was synthesized by five-step reactions which included esterification, hydroxyl protection, anionic ring-opening polymerization, hydrosilylation and deprotection. The prepared compounds in each step were characterized. The results showed that at each step synthesis was successfully carried out and objective products could be achieved.

ChemInform Abstract: Selective Protection of the C7 and C10 Hydroxyl Groups in 10-Deacetyl Baccatin III

ChemInform ◽  
2010 ◽  
Vol 29 (30) ◽  
pp. no-no
Author(s):  
R. A. HOLTON ◽  
Z. ZHANG ◽  
P. A. CLARKE ◽  
H. NADIZADEH ◽  
D. J. PROCTER
Keyword(s):  
Hydroxyl Groups ◽  
Baccatin Iii ◽  
Selective Protection

scholarly journals SYNTHESIS OF 1,2;3,4-DI-O-ISOPROPYLIDENE-6- O-[4-(1H-AZOL-1-YLMETHYL) PHENYL]- ¯-D-GALACTOPYRANOSE AND 1,2,3,4-TETRA-O-ACETYL-6- O-[4-(1H-AZOL-1- YLMETHYL)PHENYL]-¯-D-GLUCOPYRANOSE

2017 ◽  
Vol 17 (5) ◽  
pp. 122-128
Author(s):  
Z.P. Belousova ◽  
P.P. Purygin ◽  
A.P. Tyurin
Keyword(s):  
Hydroxyl Group ◽  
Hydroxyl Groups ◽  
Secondary Hydroxyl ◽  
Primary Hydroxyl ◽  
Derivatives Of

Derivatives of D-galactose and D-glucose substituted for the primary hydroxyl group, which contain an aglycone azolylmethylphenyl fragments (for imidazole, 1,2,4-triazole, benzimidazole and benzotriazole) has been synthesized. Toprotect the secondary hydroxyl groups of monosaccharides acetyl and isopropylidene groups were used.

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