Design, Synthesis and Biological Evaluation of Nitro Oxide Donating N-Hydroxycinnamamide Derivatives as Histone Deacetylase Inhibitors

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.c14-00449 ◽

2014 ◽

Vol 62 (12) ◽

pp. 1185-1191 ◽

Author(s):

Shiliang Tu ◽

Hang Yuan ◽

Jie Hu ◽

Chengguang Zhao ◽

Rui Chai ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation

ACS Omega ◽

10.1021/acsomega.0c05870 ◽

2021 ◽

Vol 6 (7) ◽

pp. 4907-4920

Author(s):

Duong T. Anh ◽

Pham-The Hai ◽

Le D. Huy ◽

Hoang B. Ngoc ◽

Trinh T. M. Ngoc ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of novel 2,4-thiazolidinedione derivatives as histone deacetylase inhibitors targeting liver cancer cell line

Medicinal Chemistry Research ◽

10.1007/s00044-011-9623-3 ◽

2011 ◽

Vol 21 (7) ◽

pp. 1156-1165 ◽

Author(s):

Rhea Mohan ◽

Ajit K. Sharma ◽

Sanjay Gupta ◽

C. S. Ramaa

Keyword(s):

Liver Cancer ◽

Cell Line ◽

Histone Deacetylase ◽

Cancer Cell ◽

Histone Deacetylase Inhibitors ◽

Cancer Cell Line ◽

Biological Evaluation ◽

Liver Cancer Cell ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of 4-piperidin-4-yl-triazole derivatives as novel histone deacetylase inhibitors

BioScience Trends ◽

10.5582/bst.2019.01055 ◽

2019 ◽

Vol 13 (2) ◽

pp. 197-203 ◽

Author(s):

He Miao ◽

Jianjun Gao ◽

Zishuo Mou ◽

Baolei Wang ◽

Li Zhang ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Triazole Derivatives ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.104023 ◽

2020 ◽

Vol 101 ◽

pp. 104023 ◽

Author(s):

Jiaoli Ding ◽

Jing Liu ◽

Zhipeng Zhang ◽

Jie Guo ◽

Maojun Cheng ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Anticancer Activities ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.08.041 ◽

2018 ◽

Vol 143 ◽

pp. 320-333 ◽

Author(s):

Rui Xie ◽

Yan Li ◽

Pingwah Tang ◽

Qipeng Yuan

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Antitumor Agents ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel histone deacetylase inhibitors based on virtual screening

Acta Pharmaceutica Sinica B ◽

10.1016/j.apsb.2011.10.002 ◽

2011 ◽

Vol 1 (4) ◽

pp. 240-247 ◽

Author(s):

Hui Lu ◽

Ya-dong Chen ◽

Bo Yang ◽

Qi-dong You

Keyword(s):

Virtual Screening ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.04.004 ◽

2013 ◽

Vol 23 (11) ◽

pp. 3200-3203 ◽

Author(s):

Ming Zhou ◽

Chengqing Ning ◽

Ruihuan Liu ◽

Yujun He ◽

Niefang Yu

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Thiazole Derivatives ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113893 ◽

2022 ◽

Vol 227 ◽

pp. 113893

Author(s):

Bei-Er Jiang ◽

Jiaxin Hu ◽

Hao Liu ◽

Zhitao Liu ◽

Yu Wen ◽

...

Keyword(s):

Histone Deacetylase ◽

Hydroxamic Acid ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Hydroxamic Acid Derivatives

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Design, synthesis and biological evaluation of novel isoindolinone derivatives as potent histone deacetylase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.02.032 ◽

2019 ◽

Vol 168 ◽

pp. 110-122 ◽

Author(s):

Xin Chen ◽

Shuang Zhao ◽

Hongmei Li ◽

Xin Wang ◽

Aixin Geng ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of histone deacetylase inhibitors possessing glutathione peroxidase-like and antioxidant activities against Alzheimer’s disease

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2018.10.022 ◽

2018 ◽

Vol 26 (21) ◽

pp. 5718-5729 ◽

Author(s):

Jinhui Hu ◽

Baijiao An ◽

Tingting Pan ◽

Zhengcunxiao Li ◽

Ling Huang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glutathione Peroxidase ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Antioxidant Activities ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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