scholarly journals Design, Synthesis, and Structure–Activity Relationships Study of N-Pyrimidyl/Pyridyl-2-thiazolamine Analogues as Novel Positive Allosteric Modulators of M3 Muscarinic Acetylcholine Receptor

2021 ◽  
Vol 69 (4) ◽  
pp. 360-373
Author(s):  
Hiroaki Tanaka ◽  
Michinori Akaiwa ◽  
Kenji Negoro ◽  
Eiji Kawaminami ◽  
Hisashi Mihara ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Muscarinic Acetylcholine Receptor ◽  
Allosteric Modulators ◽  
Design Synthesis ◽  
Muscarinic Acetylcholine ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Positive Allosteric Modulators

scholarly journals Characterization of novel selective positive allosteric modulators (PAMS) of the M4 muscarinic acetylcholine receptor (mAChR)

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Ashley Elizabeth Brady ◽  
Tom M Bridges ◽  
Carrie K Jones ◽  
Jana K Shirey ◽  
Craig W Lindsley ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Muscarinic Acetylcholine Receptor ◽  
Allosteric Modulators ◽  
Muscarinic Acetylcholine ◽  
Positive Allosteric Modulators

scholarly journals Effects of M1 and M4 muscarinic acetylcholine receptor positive allosteric modulators on sleep and cognition in rodents

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Robert W Gould ◽  
Michael T Nedelcovych ◽  
Michael D Grannan ◽  
Michael Bubser ◽  
Michael R Wood ◽  
...  
Keyword(s):  
Acetylcholine Receptor ◽  
Muscarinic Acetylcholine Receptor ◽  
Allosteric Modulators ◽  
Muscarinic Acetylcholine ◽  
Positive Allosteric Modulators ◽  
Sleep And Cognition
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