THE EFFECT OF PRE-EXERCISE MEDIUM-CHAIN TRIGLYCERIDE INGESTION ON MUSCLE GLYCOGEN UTILIZATION DURING HIGH INTENSITY EXERCISE

1995 ◽  
Vol 27 (Supplement) ◽  
pp. S203 ◽  
Author(s):  
J. F. Horowitz ◽  
R. Mora-Rodriguez ◽  
E. F. Coyle
Keyword(s):  
Muscle Glycogen ◽  
High Intensity ◽  
Medium Chain Triglyceride ◽  
High Intensity Exercise ◽  
Medium Chain ◽  
Glycogen Utilization

Preexercise medium-chain triglyceride ingestion does not alter muscle glycogen use during exercise

2000 ◽  
Vol 88 (1) ◽  
pp. 219-225 ◽  
Author(s):  
Jeffrey F. Horowitz ◽  
Ricardo Mora-Rodriguez ◽  
Lauri O. Byerley ◽  
Edward F. Coyle
Keyword(s):  
Muscle Glycogen ◽  
High Intensity ◽  
Vastus Lateralis ◽  
Medium Chain Triglyceride ◽  
High Intensity Exercise ◽  
Total Carbohydrate ◽  
Glycogen Concentration ◽  
Medium Chain ◽  
Stable Isotope Dilution ◽  
Increase Glucose Uptake

This investigation determined whether ingestion of a tolerable amount of medium-chain triglycerides (MCT; ∼25 g) reduces the rate of muscle glycogen use during high-intensity exercise. On two occasions, seven well-trained men cycled for 30 min at 84% maximal O2 uptake. Exactly 1 h before exercise, they ingested either 1) carbohydrate (CHO; 0.72 g sucrose/kg) or 2) MCT+CHO [0.36 g tricaprin (C10:0)/kg plus 0.72 g sucrose/kg]. The change in glycogen concentration was measured in biopsies taken from the vastus lateralis before and after exercise. Additionally, glycogen oxidation was calculated as the difference between total carbohydrate oxidation and the rate of glucose disappearance from plasma (Rd glucose), as measured by stable isotope dilution techniques. The change in muscle glycogen concentration was not different during MCT+CHO and CHO (42.0 ± 4.6 vs. 38.8 ± 4.0 μmol glucosyl units/g wet wt). Furthermore, calculated glycogen oxidation was also similar (331 ± 18 vs. 329 ± 15 μmol ⋅ kg− 1 ⋅ min− 1). The coingestion of MCT+CHO did increase ( P < 0.05) Rd glucose at rest compared with CHO (26.9 ± 1.5 vs. 20.7 ± 0.7 μmol ⋅kg− 1 ⋅ min− 1), yet during exercise Rd glucose was not different during the two trials. Therefore, the addition of a small amount of MCT to a preexercise CHO meal did not reduce muscle glycogen oxidation during high-intensity exercise, but it did increase glucose uptake at rest.

NO EFFECT OF MEDIUM CHAIN TRIGLYCERIDE (MCT) INGESTION DURING PROLONGED EXERCISE ON MUSCLE GLYCOGEN UTILIZATION*

1995 ◽  
Vol 27 (Supplement) ◽  
pp. S101 ◽  
Author(s):  
L. Borghouts ◽  
A. E. Jeukendrup ◽  
W. H.M. Saris ◽  
F. Brouns ◽  
A. J.M. Wagenmakers
Keyword(s):  
Muscle Glycogen ◽  
Prolonged Exercise ◽  
Medium Chain Triglyceride ◽  
Medium Chain ◽  
Glycogen Utilization

Muscle Glycogen Metabolism and High-Intensity Exercise Performance: A Narrative Review

2021 ◽  
Author(s):  
Jeppe F. Vigh-Larsen ◽  
Niels Ørtenblad ◽  
Lawrence L. Spriet ◽  
Kristian Overgaard ◽  
Magni Mohr
Keyword(s):  
Muscle Glycogen ◽  
Exercise Performance ◽  
High Intensity ◽  
Glycogen Metabolism ◽  
Narrative Review ◽  
High Intensity Exercise

scholarly journals Effect of Ingestion of Medium-Chain Triacylglycerols on Moderate- and High-Intensity Exercise in Recreational Athletes

2009 ◽  
Vol 55 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Naohisa NOSAKA ◽  
Yoshie SUZUKI ◽  
Akira NAGATOISHI ◽  
Michio KASAI ◽  
Jian WU ◽  
...  
Keyword(s):  
High Intensity ◽  
High Intensity Exercise ◽  
Medium Chain ◽  
Recreational Athletes

High‐intensity exercise and muscle glycogen availability in humans

1999 ◽  
Vol 165 (4) ◽  
pp. 337-345 ◽  
Author(s):  
Balsom ◽  
Gaitanos ◽  
Söderlund ◽  
Ekblom
Keyword(s):  
Muscle Glycogen ◽  
High Intensity ◽  
High Intensity Exercise

scholarly journals Hyperinsulinaemia and hyperglycaemia promote glucose utilization and storage during low- and high-intensity exercise

2019 ◽  
Vol 120 (1) ◽  
pp. 127-135 ◽  
Author(s):  
Hamid Mohebbi ◽  
Iain T. Campbell ◽  
Marie A. Keegan ◽  
James J. Malone ◽  
Andrew T. Hulton ◽  
...  
Keyword(s):  
Muscle Glycogen ◽  
High Intensity ◽  
Insulin Infusion ◽  
Glucose Utilization ◽  
High Intensity Exercise ◽  
Glucose Disposal ◽  
Plasma Insulin Concentration ◽  
Severe Exercise ◽  
Intensity Of Exercise ◽  
And Storage

Abstract Purpose The effect of hyperglycaemia with and without additional insulin was explored at a low and high intensity of exercise (40% vs 70% VO2peak) on glucose utilization (GUR), carbohydrate oxidation, non-oxidative glucose disposal (NOGD), and muscle glycogen. Methods Eight healthy trained males were exercised for 120 min in four trials, twice at 40% VO2peak and twice at 70% VO2peak, while glucose was infused intravenously (40%G; 70%G) at rates to “clamp” blood glucose at 10 mM. On one occasion at each exercise intensity, insulin was also infused at 40 mU/m2/per min (i.e. 40%GI and 70%GI). The glucose and insulin infusion began 30 min prior to exercise and throughout exercise. A muscle biopsy was taken at the end of exercise for glycogen analysis. Results Hyperglycaemia significantly elevated plasma insulin concentration (p < 0.001), although no difference was observed between the exercise intensities. Insulin infusion during both mild and severe exercise resulted in increased insulin concentrations (p < 0.01) and GUR (p < 0.01) compared with glucose (40%GI by 25.2%; 70%GI by 26.2%), but failed to significantly affect carbohydrate, fat and protein oxidation. NOGD was significantly higher for GI trials at both intensities (p < 0.05) with storage occurring during both lower intensities (62.7 ± 19.6 g 40%GI; 127 ± 20.7 g 40%GI) and 70%GI (29.0 ± 20.0 g). Muscle glycogen concentrations were significantly depleted from rest (p < 0.01) after all four trials. Conclusion Hyperinsulinaemia in the presence of hyperglycaemia during both low- and high-intensity exercise promotes GUR and NOGD, but does not significantly affect substrate oxidation.

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