scholarly journals A-33 Clinical Case Slide - Upper Extremity I

2013 ◽  
Vol 45 (5S) ◽  
pp. 19-20
Author(s):  
Robin D. Clark ◽  
Cynthia J. Curry

This chapter reviews background information about the incidence, epidemiology, genetics, and other anomalies associated with common congenital anomalies of the upper extremity. The discussion reviews the differential diagnosis of transverse, longitudinal (amelia, radial, ulnar), intercalary (phocomelia), and central (split hand/foot) defects of the radius and ulna and combined upper and lower extremity defects. The chapter summarizes common causes of upper extremity anomalies, including amniotic band disruption sequence, teratogenic agents (misoprostol, thalidomide, valproic acid), vascular disruption, chromosome anomalies, and Mendelian congenital malformation syndromes, and it gives recommendations for evaluation and management. A clinical case presentation features an infant with Holt–Oram syndrome.


2016 ◽  
Vol 7 (2) ◽  
pp. ar.2016.7.0159
Author(s):  
Karen Ganacias ◽  
Sarah Spriet ◽  
Taylor A. Banks

Background Vesicular rashes are associated with a variety of infectious and noninfectious causes. Objective To discuss the differential diagnoses of vesicular rashes. Methods We present the clinical case of an adult woman who was immunocompetent and who developed several clear fluid-filled vesicles on her upper extremity within days of receiving the varicella zoster vaccine. Over the next several days, the skin eruption generalized, and she developed new lesions in various stages of healing. Results After a detailed history and further studies were obtained, a final diagnosis was made. Conclusion In patients who have recently been vaccinated, a high index of suspicion for an adverse vaccine reaction should be maintained.


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