scholarly journals Comparison of Body Composition Quantification Methods in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 985-986
Author(s):  
Zachary L. Chaplow ◽  
Brian C. Focht ◽  
Alexander R. Lucas ◽  
Elizabeth Grainger ◽  
Christina Simpson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Composition ◽  
Cancer Patients ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation

scholarly journals Endurance training improves insulin sensitivity and body composition in prostate cancer patients treated with androgen deprivation therapy

2013 ◽  
Vol 20 (5) ◽  
pp. 621-632 ◽  
Author(s):  
Thine Hvid ◽  
Kamilla Winding ◽  
Anders Rinnov ◽  
Thomas Dejgaard ◽  
Carsten Thomsen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Composition ◽  
Insulin Sensitivity ◽  
Endurance Training ◽  
Cancer Patients ◽  
Androgen Deprivation Therapy ◽  
Systemic Inflammation ◽  
Muscle Protein ◽  
Androgen Deprivation ◽  
Whole Body

Insulin resistance and changes in body composition are side effects of androgen deprivation therapy (ADT) given to prostate cancer patients. The present study investigated whether endurance training improves insulin sensitivity and body composition in ADT-treated prostate cancer patients. Nine men undergoing ADT for prostate cancer and ten healthy men with normal testosterone levels underwent 12 weeks of endurance training. Primary endpoints were insulin sensitivity (euglycemic–hyperinsulinemic clamps with concomitant glucose-tracer infusion) and body composition (dual-energy X-ray absorptiometry and magnetic resonance imaging). The secondary endpoint was systemic inflammation. Statistical analysis was carried out using two-way ANOVA. Endurance training increased VO2max(ml(O2)/min per kg) by 11 and 13% in the patients and controls respectively (P<0.0001). The patients and controls demonstrated an increase in peripheral tissue insulin sensitivity of 14 and 11% respectively (P<0.05), with no effect on hepatic insulin sensitivity (P=0.32). Muscle protein content of GLUT4 (SLC2A4) and total AKT (AKT1) was also increased in response to the training (P<0.05 andP<0.01 respectively). Body weight (P<0.0001) and whole-body fat mass (FM) (P<0.01) were reduced, while lean body mass (P=0.99) was unchanged. Additionally, reductions were observed in abdominal (P<0.01), subcutaneous (P<0.05), and visceral (P<0.01) FM amounts. The concentrations of plasma markers of systemic inflammation were unchanged in response to the training. No group×time interactions were observed, except for thigh intermuscular adipose tissue (IMAT) (P=0.01), reflecting a significant reduction in the amount of IMAT in the controls (P<0.05) not observed in the patients (P=0.64). In response to endurance training, ADT-treated prostate cancer patients exhibited improved insulin sensitivity and body composition to a similar degree as eugonadal men.

Exercise Improves V˙O2max and Body Composition in Androgen Deprivation Therapy–treated Prostate Cancer Patients

2017 ◽  
Vol 49 (8) ◽  
pp. 1503-1510 ◽  
Author(s):  
BRADLEY A. WALL ◽  
DANIEL A. GALVãO ◽  
NAEEM FATEHEE ◽  
DENNIS R. TAAFFE ◽  
NIGEL SPRY ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Composition ◽  
Cancer Patients ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation

Effects of strength training on body composition, physical functioning, and quality of life in prostate cancer patients during androgen deprivation therapy

2015 ◽  
Vol 54 (10) ◽  
pp. 1805-1813 ◽  
Author(s):  
Tormod S. Nilsen ◽  
Truls Raastad ◽  
Eva Skovlund ◽  
Kerry S. Courneya ◽  
Carl W. Langberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Body Composition ◽  
Strength Training ◽  
Cancer Patients ◽  
Androgen Deprivation Therapy ◽  
Physical Functioning ◽  
Androgen Deprivation

scholarly journals Effects of a Lifestyle Intervention on Change in Body Composition in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy

2018 ◽  
Vol 50 (5S) ◽  
pp. 257
Author(s):  
Zachary L. Chaplow ◽  
Brian C. Focht ◽  
Alexander R. Lucas ◽  
Elizabeth Grainger ◽  
Christina Simpson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Composition ◽  
Cancer Patients ◽  
Lifestyle Intervention ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation

598: Increased Risk of Newly Diagnosed Comorbidities in Prostate Cancer Patients Treated with Androgen Deprivation Therapy

2007 ◽  
Vol 177 (4S) ◽  
pp. 200-200 ◽  
Author(s):  
Andrea Gallina ◽  
Pierre I. Karakiewicz ◽  
Jochen Walz ◽  
Claudio Jeldres ◽  
Quoc-Dien Trinh ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation ◽  
Newly Diagnosed ◽  
Increased Risk
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