Natural History of Stent Edge Dissection, Tissue Protrusion and Incomplete Stent Apposition Detectable Only on Optical Coherence Tomography After Stent Implantation

Purpose: To investigate the natural history of idiopathic epiretinal membrane (ERM) in eyes with good visual function using optical coherence tomography (OCT). Methods: Sixty-two eyes of 58 patients with idiopathic ERM, visual acuity of 20/40 or better, and no significant metamorphopsia were included. The best corrected visual acuity (BCVA), central macular thickness (CMT), membrane configuration, and ellipsoid zone signal data over 24 months were retrospectively analyzed. Based on OCT findings, ERM configurations were categorized as global attachment (GA), partial attachment (PA), pseudohole, and vitreomacular traction (VMT). Results: The mean BCVA and CMT did not change significantly between baseline and 24 months. GA, PA, pseudohole, and VMT types were observed in 33, 19, 9, and 1 eye at baseline, and in 20, 22, 10, and 1 eye at 24 months, respectively. A membrane configuration change was noted in 24 eyes (38.7%) during follow-up, and the distribution shifted from GA to the other types (p < 0.001). Six eyes had visual loss due to membrane progression, and 4 eyes had spontaneous membrane separation. Of the 10 eyes with progression or separation, 6 were of the PA type. Conclusions: Although the BCVA remains stable over 2 years in most idiopathic ERM eyes with good visual function at baseline, the membrane configuration may change, affecting visual acuity. The GA type would be an early stage, and the PA type is prone to changes in visual acuity.

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TCT-503 Cut-off value of strut vessel distance on resolution of acute incomplete stent apposition at one month using serial optical coherence tomography after cobalt- chromium everolimus-eluting stent implantation in patients with stable coronary artery disease

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2018.08.1680 ◽

2018 ◽

Vol 72 (13) ◽

pp. B202

Author(s):

Hideto Oda ◽

Tomonori Itoh ◽

Yohei Uchimura ◽

Yuya Taguchi ◽

Kyosuke Kaneko ◽

...

Keyword(s):

Coronary Artery Disease ◽

Optical Coherence Tomography ◽

Coronary Artery ◽

Stent Implantation ◽

Stable Coronary Artery Disease ◽

Optical Coherence ◽

Cobalt Chromium ◽

Incomplete Stent Apposition ◽

Artery Disease

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Natural History of Drusen Morphology in Age-Related Macular Degeneration Using Spectral Domain Optical Coherence Tomography

Ophthalmology ◽

10.1016/j.ophtha.2011.05.008 ◽

2011 ◽

Vol 118 (12) ◽

pp. 2434-2441 ◽

Cited By ~ 87

Author(s):

Zohar Yehoshua ◽

Fenghua Wang ◽

Philip J. Rosenfeld ◽

Fernando M. Penha ◽

William J. Feuer ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Natural History ◽

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Spectral Domain ◽

Optical Coherence ◽

Age Related ◽

History Of

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The natural history of lamellar macular holes: a spectral domain optical coherence tomography study

Graefe s Archive for Clinical and Experimental Ophthalmology ◽

10.1007/s00417-012-2044-2 ◽

2012 ◽

Vol 251 (2) ◽

pp. 467-475 ◽

Cited By ~ 59

Author(s):

Ferdinando Bottoni ◽

Antonio Peroglio Deiro ◽

Andrea Giani ◽

Claudia Orini ◽

Mario Cigada ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Natural History ◽

Spectral Domain ◽

Optical Coherence ◽

Macular Holes ◽

History Of

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TCT-601 Serial Optical coherence tomography assessment of natural history of silent plaque rupture

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2016.09.740 ◽

2016 ◽

Vol 68 (18) ◽

pp. B244

Author(s):

Teruyoshi Kume ◽

Ryotaro Yamada ◽

Kenzo Fukuhara ◽

Terumasa Koyama ◽

Yutaka Goryo ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Natural History ◽

Plaque Rupture ◽

Optical Coherence ◽

History Of

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FREQUENCY, PREDICTORS, AND NATURAL HISTORY OF STENT EDGE DISSECTION: AN OPTICAL COHERENCE TOMOGRAPHY STUDY

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(14)61796-4 ◽

2014 ◽

Vol 63 (12) ◽

pp. A1793

Author(s):

Tsunenari Soeda ◽

Shiro Uemura ◽

Harold Dauerman ◽

Stephen Lee ◽

Seung-Jung Park ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Natural History ◽

Optical Coherence ◽

History Of

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Abstract 12801: Angled Lesions Have Higher Incidence of Vascular Injury and Incomplete Stent Apposition, as Compared to Non-Angled Lesions, Following Stenting: An Optical Coherence Tomography Study

Circulation ◽

10.1161/circ.130.suppl_2.12801 ◽

2014 ◽

Vol 130 (suppl_2) ◽

Author(s):

Yoshiyasu Minami ◽

Shiro Uemura ◽

Stephen Lee ◽

Soo Joong Kim ◽

Chang-Bum Park ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Stent Implantation ◽

Independent Predictor ◽

Ex Vivo ◽

Vascular Complications ◽

Optical Coherence ◽

Incomplete Stent Apposition ◽

Vessel Injury ◽

Coronary Lesions ◽

Type Of Injury

Backgrounds: Angled lesions are reported to be associated with worse procedural and clinical outcomes. Recent ex vivo studies have demonstrated that an angled arterial wall is exposed to imbalanced mechanical stress, which can cause vessel injuries and incomplete stent apposition (ISA) following stent implantation. Hypothesis: We tested the hypothesis that the angled coronary lesions, compared to non-angled lesions, would have higher incidence of vascular complications and ISA following stent implantation using optical coherence tomography (OCT) in patients. Methods: A total of 245 lesions treated with a single DES [95 zotarolimus-eluting stent (ZES) and 150 everolimus-eluting stent (EES)] were analyzed using OCT. An angled lesion was defined as a lesion on a curve ≥45° (n=59) on an angiogram and non-angled lesion on a curve <45° (n=186). The frequency was expressed as the percentage of stents with at least one type of injury or strut malapposition. Vessel injury included edge dissection, in-stent dissection, thrombus, and tissue protrusion. ISA was defined when the distance between the center of strut and the vessel wall was >100μm in ZES and >90um in EES. Results: The incidence of edge dissection and tissue protrusion was not significantly different between the groups. However, the incidence of in-stent dissection (84.7% vs 63.4%, P<0.01), thrombus (55.9% vs 35.5%, P<0.01) and ISA (76.3% vs 44.6%, P<0.001) was significantly higher in the angled group. The multivariate analysis demonstrated that the lesion on angle ≥60° was the independent predictor for in-stent dissection [Odds ratio (OR) 4.37, P=0.03] and ISA [OR 7.37, P<0.01], and that the angle ≥45° was the independent predictor for thrombus [OR 2.94, P=0.01]. There was no difference in the OCT findings between the ZES and EES groups. Conclusion: Angled coronary lesions had higher incidence of in-stent dissection, thrombus and ISA compared with non-angled lesions following DES implantation as assessed by OCT.

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