Draft ICH guideline S7B: Guideline on safety pharmacology studies for assessing the potential for delayed ventricular repolarization (QT interval prolongation) by human pharmaceuticals.

Folia Pharmacologica Japonica ◽

10.1254/fpj.121.377 ◽

2003 ◽

Vol 121 (6) ◽

pp. 377-383 ◽

Author(s):

Munehiro HASHIMOTO

Keyword(s):

Qt Interval ◽

Ventricular Repolarization ◽

Interval Prolongation ◽

Safety Pharmacology ◽

Qt Interval Prolongation ◽

Download Full-text

Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond

10.3389/978-2-88945-539-3 ◽

2018 ◽

Keyword(s):

Risk Assessment ◽

Qt Interval ◽

Interval Prolongation ◽

Safety Pharmacology ◽

Qt Interval Prolongation

Download Full-text

Comparison of electrocardiographic analysis for risk of QT interval prolongation using safety pharmacology and toxicological studies

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2009.05.006 ◽

2009 ◽

Vol 60 (2) ◽

pp. 107-116 ◽

Author(s):

B.D. Guth ◽

A.S. Bass ◽

R. Briscoe ◽

S. Chivers ◽

M. Markert ◽

...

Keyword(s):

Qt Interval ◽

Interval Prolongation ◽

Safety Pharmacology ◽

Qt Interval Prolongation ◽

Toxicological Studies

Download Full-text

Drug-Induced QT Prolongation: Individual Susceptibility and Regulatory Issues Related to Safety Pharmacology 2. Evaluation of QT Interval Prolongation in Non-Clinical Studies according to ICH S7A and S7B and its Questions at Issue

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics ◽

10.3999/jscpt.37.4_201 ◽

2006 ◽

Vol 37 (4) ◽

pp. 201-206 ◽

Author(s):

KENTARO ANDO

Keyword(s):

Clinical Studies ◽

Qt Interval ◽

Qt Prolongation ◽

Interval Prolongation ◽

Drug Induced ◽

Regulatory Issues ◽

Safety Pharmacology ◽

Individual Susceptibility ◽

Qt Interval Prolongation

Download Full-text

Drug-Induced QT Prolongation: Individual Susceptibility and Regulatory Issues Related to Safety Pharmacology 3. Assessment of Drug-Induced QT Interval Prolongation in Non-Clinical Test

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics ◽

10.3999/jscpt.37.4_207 ◽

2006 ◽

Vol 37 (4) ◽

pp. 207-214 ◽

Author(s):

ATSUSHI SUGIYAMA

Keyword(s):

Qt Interval ◽

Qt Prolongation ◽

Clinical Test ◽

Interval Prolongation ◽

Drug Induced ◽

Regulatory Issues ◽

Safety Pharmacology ◽

Individual Susceptibility ◽

Qt Interval Prolongation

Download Full-text

Editorial: Safety Pharmacology – Risk Assessment QT Interval Prolongation and Beyond

Frontiers in Physiology ◽

10.3389/fphys.2018.00678 ◽

2018 ◽

Vol 9 ◽

Author(s):

Eleonora Grandi ◽

Stefano Morotti ◽

Esther Pueyo ◽

Blanca Rodriguez

Keyword(s):

Risk Assessment ◽

Qt Interval ◽

Interval Prolongation ◽

Safety Pharmacology ◽

Qt Interval Prolongation

Download Full-text

QT PRODACT: Usability of Miniature Pigs in Safety Pharmacology Studies: Assessment for Drug-Induced QT Interval Prolongation

Journal of Pharmacological Sciences ◽

10.1254/jphs.qt-c13 ◽

2005 ◽

Vol 99 (5) ◽

pp. 501-511 ◽

Author(s):

Mayumi Kano ◽

Tohru Toyoshi ◽

Sakae Iwasaki ◽

Masami Kato ◽

Masayoshi Shimizu ◽

...

Keyword(s):

Qt Interval ◽

Interval Prolongation ◽

Drug Induced ◽

Safety Pharmacology ◽

Miniature Pigs ◽

Qt Interval Prolongation

Download Full-text

Drug-Induced QT Interval Prolongation: Mechanisms, Risk Factors, Genetics and Clinical Management

Journal of Basic and Clinical Health Sciences ◽

10.30621/jbachs.2019.712 ◽

2019 ◽

Author(s):

Gözde Aktürk ◽

Şule Kalkan

Keyword(s):

Risk Factors ◽

Clinical Management ◽

Qt Interval ◽

Interval Prolongation ◽

Drug Induced ◽

Qt Interval Prolongation

Download Full-text

Predictors of arrhythmia other than QT interval prolongation and the use of β-blocker therapy in the coronavirus disease 2019 pandemic

Kardiologia Polska ◽

10.33963/kp.15563 ◽

2020 ◽

Vol 78 (7-8) ◽

pp. 796-796

Author(s):

Hatice Tolunay

Keyword(s):

Qt Interval ◽

Interval Prolongation ◽

Blocker Therapy ◽

Qt Interval Prolongation ◽

Download Full-text

Faculty Opinions recommendation of Postoperative QT interval prolongation in patients undergoing noncardiac surgery under general anesthesia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717951615.793456917 ◽

2012 ◽

Author(s):

Benedikt Preckel

Keyword(s):

General Anesthesia ◽

Qt Interval ◽

Noncardiac Surgery ◽

Interval Prolongation ◽

Qt Interval Prolongation

Download Full-text

Concentration‐QT modeling shows no evidence of clinically significant QT interval prolongation with capivasertib at expected therapeutic concentrations

British Journal of Clinical Pharmacology ◽

10.1111/bcp.15006 ◽

2021 ◽

Author(s):

Veronika Voronova ◽

Marie Cullberg ◽

Philip Delff ◽

Joanna Parkinson ◽

Corina Dota ◽

...

Keyword(s):

Qt Interval ◽

Interval Prolongation ◽

Qt Interval Prolongation ◽

Clinically Significant

Download Full-text