scholarly journals STUDIES ON MECHANISM OF SEX DIFFERENCE IN DRUG-OXIDIZING ACTIVITY OF LIVER MICROSOMES

1968 ◽  
Vol 18 (4) ◽  
pp. 482-489 ◽  
Author(s):  
RYUICHI KATO ◽  
AKIRA TAKANAKA ◽  
MIGHIKO TAKAYANAGI
Keyword(s):  
Sex Difference ◽  
Liver Microsomes

Sex difference in the O-dealkylation activity of 7-hydroxycoumarin O-alkyl derivatives in liver microsomes of rats

1980 ◽  
Vol 29 (7) ◽  
pp. 1015-1022 ◽  
Author(s):  
Tetsuya Kamataki ◽  
Mebae Ando ◽  
Yasushi Yamazoe ◽  
Kenji Ishii ◽  
Ryuichi Kato
Keyword(s):  
Sex Difference ◽  
Liver Microsomes ◽  
Alkyl Derivatives

Position selective sex difference in imipramine metabolism in rat liver microsomes

1985 ◽  
Vol 34 (6) ◽  
pp. 898-900 ◽  
Author(s):  
Masato Chiba ◽  
Eri Nishihara ◽  
Shoichi Fujita ◽  
Tokuji Suzuki
Keyword(s):  
Sex Difference ◽  
Rat Liver ◽  
Liver Microsomes ◽  
Rat Liver Microsomes ◽  
Imipramine Metabolism

Sex difference in responsiveness to aztreonam of monooxygenase system in liver microsomes from rats

1987 ◽  
Vol 36 (7) ◽  
pp. 1053-1057 ◽  
Author(s):  
Tohru Horie ◽  
Mitsukazu Kitada ◽  
Yoshio Tanabe ◽  
Yoshio Kanakubo
Keyword(s):  
Sex Difference ◽  
Liver Microsomes ◽  
Monooxygenase System

Sex difference in N-demethylation activity of ethylmorphine in rat liver microsomes

1980 ◽  
Vol 97 (4) ◽  
pp. 1527-1534 ◽  
Author(s):  
Mitsukazu Kitada ◽  
Shigeru Omori ◽  
Takashi Igarashi ◽  
Yoshio Kanakubo ◽  
Haruo Kitagawa
Keyword(s):  
Sex Difference ◽  
Rat Liver ◽  
Liver Microsomes ◽  
Rat Liver Microsomes ◽  
Demethylation Activity

SEX DIFFERENCES IN THE METABOLISM OF OESTROGENS BY RAT LIVER MICROSOMES

1965 ◽  
Vol 32 (1) ◽  
pp. 91-98 ◽  
Author(s):  
P. H. JELLINCK ◽  
IRENE LUCIEER
Keyword(s):  
Sex Differences ◽  
Sex Difference ◽  
Enzyme System ◽  
Liver Microsomes ◽  
Water Soluble ◽  
Female Rats ◽  
Male Rats ◽  
Hormonal Status ◽  
Rat Liver Microsomes ◽  
Soluble Material

SUMMARY Liver microsomes derived from male rats were shown to convert a higher proportion of [14C]oestrone and [14C]oestradiol to water-soluble products than did similar preparations from female rats. This sex difference became apparent at maturity and could be influenced by castration or treatment with sex hormones. The increased formation of water-soluble material by male rats was accompanied by an increase in the yield of 2-hydroxyoestradiol and other ether-soluble metabolites but no sex difference in oestrogen metabolism was detected in mice or guinea-pigs and the effect was less pronounced with [14C]stilboestrol as substrate. The enzyme system influenced by the hormonal status of the animals was present in the microsomes and showed similarities to the non-specific oxygenases which hydroxylate steroids and a number of drugs.

Sex difference in the phospholipid composition of rat liver microsomes

1975 ◽  
Vol 24 (2) ◽  
pp. 301-303 ◽  
Author(s):  
Helen Belina ◽  
Stanley D. Cooper ◽  
Rose Farkas ◽  
George Feuer
Keyword(s):  
Sex Difference ◽  
Rat Liver ◽  
Liver Microsomes ◽  
Phospholipid Composition ◽  
Rat Liver Microsomes
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