scholarly journals Coronary artery anomalies and aortic valve morphology in the Syrian hamster

2000 ◽  
Vol 34 (2) ◽  
pp. 145-154 ◽  
Author(s):  
M. C. Fernández ◽  
A. C. Durán ◽  
R. Real ◽  
D. López ◽  
B. Fernández ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Aortic Valve ◽  
Syrian Hamster ◽  
Left Coronary Artery ◽  
Coronary Artery Anomalies ◽  
Aortic Valves ◽  
Aortic Sinus ◽  
Bicuspid Aortic Valves ◽  
Anomalous Coronary ◽  
The Continuum

In the Syrian hamster, anomalies in the origin of the left coronary artery are significantly associated with the bicuspid condition of the aortic valve. In this species, bicuspid aortic valves are expressions of a trait, the variation of which takes the form of a phenotypic continuum, ranging from a tricuspid aortic valve with no commissural fusion to a bicuspid aortic valve with the aortic sinuses located in ventrodorsal orientation and devoid of any raphe. The intermediate stages of the continuum are represented by tricuspid aortic valves with a more or less extensive fusion of the ventral commissure and bicuspid aortic valves with a more or less developed raphe located in the ventral aortic sinus. The present study was designed to decide whether there is a gap between tricuspid and bicuspid aortic valves regarding the incidence of coronary artery anomalies, or whether this incidence varies according to the different tricuspid and bicuspid morpho types of the continuum. The study was carried out in Syrian hamsters belonging to a single inbred family with a high incidence of tricuspid aortic valves with fusion of the ventral commissure, bicuspid aortic valves, and anomalies in the origin of the left coronary artery, i.e. single right coronary artery ostium in aorta, anomalous origin of the left coronary artery from the pulmonary artery, and anomalous origin of the left coronary artery from the dorsal aortic sinus. The specimens were examined by means of a stereomicroscope and, in several cases; scanning electron microscopy was also used. The relationships between anomalous coronary artery patterns and aortic valve morphologies were tested using a logistic regression model. The results obtained indicate that there is no discontinuity between tricuspid and bicuspid aortic valves regarding the incidence of coronary artery anomalies. The probability of occurrence of anomalous coronary artery patterns increases continuously according to the deviation degree of the aortic valve from its normal (tricuspid) design. The present findings suggest that in the Syrian hamster, the morphogenetic mechanisms involved in the formation of congenital anomalous aortic valves and anomalies in the origin of the left coronary artery, respectively, are strongly related from an aetiological viewpoint.

Coronary artery anomalies and bicuspid aortic valves in the Syrian hamster

1991 ◽  
Vol 86 (2) ◽  
pp. 148-153 ◽  
Author(s):  
V. Sans-Coma ◽  
J. M. Arqué ◽  
A. C. Durán ◽  
M. Cardo ◽  
B. Fernández
Keyword(s):  
Coronary Artery ◽  
Syrian Hamster ◽  
Coronary Artery Anomalies ◽  
Aortic Valves ◽  
Bicuspid Aortic Valves

scholarly journals Left coronary artery anatomy in patients with bicuspid aortic valves.

Heart ◽  
1978 ◽  
Vol 40 (5) ◽  
pp. 489-493 ◽  
Author(s):  
A D Johnson ◽  
J H Detwiler ◽  
C B Higgins
Keyword(s):  
Coronary Artery ◽  
Left Coronary Artery ◽  
Aortic Valves ◽  
Coronary Artery Anatomy ◽  
Bicuspid Aortic Valves

The Ross procedure performed in the setting of congenitally bifoliate aortic valve with anomalous right coronary artery

2005 ◽  
Vol 15 (2) ◽  
pp. 213-215 ◽  
Author(s):  
Masayuki Morikawa ◽  
Ko Bando ◽  
Shinji Sato
Keyword(s):  
Coronary Artery ◽  
Aortic Valve ◽  
Coronary Arteries ◽  
Right Coronary Artery ◽  
Left Coronary Artery ◽  
Ross Procedure ◽  
Aortic Sinus ◽  
Anomalous Artery ◽  
Atrioventricular Groove ◽  
The Right

We treated successfully using the Ross procedure a 14-year old with a congenitally stenotic bifoliate aortic valve associated with anomalous origin of the right coronary artery. The anomalous artery arose from the same aortic sinus that gave rise to the main stem of the left coronary artery, and reached the right atrioventricular groove by traversing the tissue plane between the aortic root and the subpulmonary infundibulum. Both coronary arteries were reimplanted using a single arterial button.

scholarly journals Anomaly of left coronary artery

2018 ◽  
Vol 41 (3) ◽  
pp. 143
Author(s):  
Finesa Hasye ◽  
Yerizal Karani
Keyword(s):  
Coronary Artery ◽  
Coronary Disease ◽  
Left Coronary Artery ◽  
Coronary Anomalies ◽  
Coronary Artery Anomalies ◽  
Invasive Angiography ◽  
Artery First ◽  
The Right ◽  
Anomalous Coronary ◽  
Anomalous Coronary Arteries

Anomalies of the coronary artery are uncommon, with a reported incidence of 0.3% to 1.3% in the coronary angiography studies routinely performed for suspected atherosclerotic coronary disease. There were 0.92% incidence of anomalous origination of the right coronary artery from the left sinus and the 0.15% incidence of anomalous origination of the left coronary artery from the right sinus. Most coronary artery anomalies are diagnosed by invasive angiography performed to investigate suspected atherosclerotic coronary disease. There are two important managements for patient with anomaly coronary artery. First, these coronary anomalies should result in exclusion from participation in intense competitive sports to reduce the risk of a cardiac event or sudden death. Second, and more importantly, treatment for wrong sinus coronary artery anomalies are revascularization can be either surgical or percutaneous. Surgical intervention should be considered for high-risk varieties of anomalous coronary arteries, as this is the only treatment that has been demonstrated to improve coronary blood flow and carries a low morbidity and mortality.

Anomalous origin of the left coronary artery from the nonfacing aortic sinus: A study in the Syrian hamster

1993 ◽  
Vol 2 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Josep M. Arqué ◽  
Gaetano Thiene ◽  
Manuel Cardo ◽  
Diego Franco ◽  
Ana C. Durán ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Syrian Hamster ◽  
Left Coronary Artery ◽  
Anomalous Origin ◽  
Aortic Sinus

MORPHOMETRIC ANATOMY AND INTRAORGAN TOPOGRAPHY OF THE CORONARY ORIFICES IN HEART OF ADULT HUMAN

2020 ◽  
pp. 40-47
Author(s):  
Андрей Аркадьевич Якимов ◽  
Евгения Германовна Дмитриева
Keyword(s):  
Coronary Artery ◽  
Blood Supply ◽  
Coronary Sinus ◽  
Left Coronary Artery ◽  
Rare Variants ◽  
Vertical Axis ◽  
Aortic Valves ◽  
Sinotubular Junction ◽  
Adult Human ◽  
The Right

Цель - выявить варианты строения и внутриорганной топографии устьев венечных артерий у взрослого человека при разных типах кровоснабжения желудочкового комплекса сердца. Материал и методы. На вскрытых через некоронарные синусы аорты 65 препаратах клапанов аорты взрослых людей изучили положение устьев венечных артерий, штангенциркулем измеряли минимальный и максимальный диаметры каждого устья, определяли их форму по соотношению диаметров. Результаты. Для устьев обеих артерий типичной была округлая, реже овальная форма. В большинстве случаев левая венечная артерия начиналась в центральной трети, правая - в центральной или задней трети «своего» синуса на уровне верхнего края полулунной заслонки или между ним и синотубулярным соединением. Локализация устьев в пределах синусов, на уровне синотубулярного соединения или выше него была редкой для обеих артерий. В 20 % случаев в правом синусе аорты спереди от устья правой венечной артерии имелось устье конусной артерии. Выводы. Типичные и редкие варианты формы правого и левого устьев, варианты их положения по вертикальной оси аорты одинаковы, варианты их положения по горизонтали различны. Зависимость вариантов формы и положения устьев от типа кровоснабжения желудочков сердца не выявлена. Objective - to reveal common and rare variants of the anatomy and intraorganic topography of the coronary orifices in normal hearts of adult human with regard to patterns of cardiac ventricular blood supply. Material and methods. On 65 specimens of aortic valves opened through non-coronary sinus, the minimal and maximal diameters of each orifice were measured with a caliper, the shape of the orifices was determined according to the ratio of the diameters, and the position of the orifices was studied. Results. The orifices of both right and left coronary arteries were mostly found to be round, less frequently oval. In most cases, the left coronary artery arose from the central third and the right artery arose from the central or posterior third of corresponding sinus at the level of the upper edge of the semilunar cusp or between the edge and the sinotubular junction. The localization of the arterial orifice within the sinuses at the level of sinotubular junction or above it was uncommon for the both arteries. In 20 % of cases, the conal artery arose with its own orifice in front of the mouth of the right coronary artery. Conclusions. Typical and rare shapes of the coronary orifices, variants of their position regarding to vertical axis of the aorta are the same, whereas variants of their position in horizontal axis are different. There is no relationship between variants of form of the orifices, position of the orifices and types of blood supply of heart ventricles.

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