scholarly journals Anomaly of left coronary artery

2018 ◽  
Vol 41 (3) ◽  
pp. 143
Author(s):  
Finesa Hasye ◽  
Yerizal Karani

Anomalies of the coronary artery are uncommon, with a reported incidence of 0.3% to 1.3% in the coronary angiography studies routinely performed for suspected atherosclerotic coronary disease. There were 0.92% incidence of anomalous origination of the right coronary artery from the left sinus and the 0.15% incidence of anomalous origination of the left coronary artery from the right sinus. Most coronary artery anomalies are diagnosed by invasive angiography performed to investigate suspected atherosclerotic coronary disease. There are two important managements for patient with anomaly coronary artery. First, these coronary anomalies should result in exclusion from participation in intense competitive sports to reduce the risk of a cardiac event or sudden death. Second, and more importantly, treatment for wrong sinus coronary artery anomalies are revascularization can be either surgical or percutaneous. Surgical intervention should be considered for high-risk varieties of anomalous coronary arteries, as this is the only treatment that has been demonstrated to improve coronary blood flow and carries a low morbidity and mortality.

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Asma Mursleen ◽  
Gregory Hartlage ◽  
Aarti Patel ◽  
Eric E. Harrison ◽  
C. Alberto Morales

Coronary anomalies can be observed in 1–1.2% of all angiograms performed. Majority of coronary anomalies are benign and do not lead to cardiac ischemia; however anomalous coronary arteries from the opposite sinus (ACAOS) are often associated with sudden cardiac deaths, typically in 0.11–0.35% of individuals who participate in vigorous physical activity (Peñalver et al., 2012). Left and right ACAOS have an incidence of 0.15% and 0.92%, respectively. Left ACAOS are often associated with higher incidence of sudden cardiac death; this could be secondary to greater territory of myocardial perfusion by the left coronary artery. ACAOS are often asymptomatic and initially present as sudden death following exertion in young athletes. The management of left ACAOS is clear and surgery is usually indicated. However there is a lack of consensus on the management of certain cases of right ACAOS. In this paper a case of 20 yo M with right coronary artery from left sinus is going to be presented with a discussion on pathophysiology, diagnosis, and management.


Author(s):  
Anita Nguyen ◽  
Ramachandra C. Reddy ◽  
Hartzell V. Schaff

Anomalous coronary arteries are relatively common, occurring in approximately 1.3% of the general population. Most variants of anomalous coronary arteries do not cause disability and have a benign course. Surgery is warranted to alleviate symptoms. However, some anomalies, such as a left coronary artery arising from the right sinus of Valsalva and passing between the great vessels or anomalous left coronary artery arising from the pulmonary artery, are considered malignant as they have been associated with sudden cardiac death or heart failure, and in these cases, surgery is indicated. Coronary artery fistulas are abnormal communications between a coronary artery and another cardiovascular structure. They are relatively rare, and surgical or transcatheter closure may be necessary in patients with large left-to-right shunts and/or regional myocardial ischaemia.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Xin Jiang ◽  
Ping Zhou ◽  
Chunlan Wen ◽  
Zhao Yin ◽  
Tao Liu ◽  
...  

Background. The prevalence of coronary artery anomalies (CAAs) is rare and varies among different countries or areas. More importantly, the symptoms exhibited by some CAAs make the diagnosis of coronary artery disease (CAD) difficult and hamper the physician from making the right intervention for CAD patients. Objective. To investigate the prevalence of CAAs in 11,267 patients from three hospitals in Southwest China. Methods. 11,267 patients who have undergone coronary angiography from three Southwest China hospitals were investigated retrospectively. Dominance patterns, prevalence, and the location of each CAA were recorded and analyzed. Results. The presence of a dominant right coronary artery (RCA) was found in 60.58% of patients. CAAs were found in 11.12% (1258) patients, and 87.66% anomalies were located in the left anterior descending (LAD) artery and its branches. Most of CAAs were found to be myocardial bridges (MBs, 1060 cases, 9.41%). Other CAAs included anomalous coronary origin (43 cases, 0.38%), coronary artery fistulas (CAFs, 36 cases, 0.32%), and coronary artery aneurysm or ectasia (119 cases, 1.06%). It also noted that most anomalies were found with RCA originating from the left coronary sinus (79.07%), most CAFs were located in the LAD and its branches (58.33%), and most coronary artery ectasias were located in the RCA (43.25%). Conclusions. CAAs in patients from Southwest China were unique compared to other studies. Recognition of these CAAs is important for accurate diagnosis and treatment choice of patients with chest pain.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
C Koppel ◽  
M R M Jongbloed ◽  
P Kies ◽  
M G Hazekamp ◽  
M J Schalij ◽  
...  

Abstract Background In literature, anomalous coronary arteries from the opposite sinus of Valsalva or opposite coronary artery (ACAOS) are reported between 2% to 39% of patients with Tetralogy of Fallot (TOF). Knowledge of coronary anatomy prior to corrective surgery is vital to avoid damage to vessels crossing the right ventricular outflow tract (RVOT). The current range of reported prevalences is broad and a general overview comparing current knowledge on anomalous coronary arteries in TOF is lacking to date. Purpose In this meta-analysis, we aim to provide a detailed overview of current knowledge on prevalence of coronary anomalies in TOF and discuss the implications for patient management. Methods PubMed, Embase and Web of Science were searched for articles on TOF and coronary anomalies. Analysis was done using Revman 5.3 (Cochrane Community, London). The primary analysis focused on the origin and proximal course of the right and left coronary arteries. Also, the prevalences of large conus arteries and coronary arteriovenous fistulas were calculated. Results Twenty-nine studies, comprising 6977 patients all together, were included for primary meta-analysis of ACAOS. 6% of TOF patients have an ACAOS. Of these anomalous vessels, 72% crosses the RVOT. 6% of patients have a large conus artery and 4% a coronary arteriovenous fistula. Other incidentally reported coronary anomalies in TOF include a left or right coronary artery originating from the pulmonary artery, an accessory left anterior descending artery, hypoplasia of the entire coronary tree and anastomoses between coronary and bronchial arteries. CT-angiography is the imaging modality of preference because of its high spatial resolution. Transthoracic echocardiography can be used in younger children as well for discerning the coronary anatomy. Most surgical approaches can be adapted to an anomalous coronary artery coursing over the RVOT. Overall prevalence of ACAOS in TOF Conclusions Coronary anomalies have a high prevalence in TOF. An ACAOS occurs in 6%, large conus arteries exist in 6% and coronary arteriovenous fistulas in 4% of cases. A substantial part crosses the RVOT. This has to be taken into account during surgery.


2020 ◽  
Vol 30 (10) ◽  
pp. 1510-1511
Author(s):  
Rachel Rosenthal ◽  
Hannah Obasi ◽  
Daniel D. Im

AbstractMyocarditis and coronary artery anomalies are both potentially life-threatening aetiologies of cardiac chest pain in children. We present a case of a young man presenting with non-exertional chest pain and subsequently found to have an anomalous origin of the right coronary artery from the left coronary sinus with an interarterial course in addition to a diagnosis of myocarditis. The patient subsequently was able to undergo surgical correction of his anomalous coronary to mitigate the risk of sudden cardiac death.


2010 ◽  
Vol 20 (S3) ◽  
pp. 44-49 ◽  
Author(s):  
Tom R. Karl ◽  
Sylvio C. J. Provenzano ◽  
Graham R. Nunn

AbstractThe most commonly reported coronary arterial malformation, in accounts of sudden deaths, is anomalous aortic origin of a coronary artery. Anomalous coronary arteries may arise from the left, right, or non-coronary sinuses of Valsalva. Importantly, although the left coronary artery from the right sinus has the worst prognosis, sudden death has been reported in all variants of origin from the various sinuses of Valsalva. This paper describes a technique that addresses all of the problems relating to anomalous aortic origin of a coronary artery from the wrong sinus of Valsalva. This technique includes the transection of the ascending aorta and pulmonary trunk, coronary arterial enlargement with a pericardial patch, and lateral translocation of the pulmonary trunk to the left pulmonary artery. Anomalous aortic origin of a coronary artery from the wrong sinus of Valsalva is a potentially lethal cardiac anomaly that can be corrected in all cases using this simplified surgical technique that addresses the major anatomic and physiological problems.


2020 ◽  
Vol 47 (2) ◽  
pp. 170-172
Author(s):  
Harini Bollempalli ◽  
Vijay G. Divakaran ◽  
Andrew C. Kontak ◽  
Patricia C. Lee

Anomalous coronary arteries are rare and often incidental findings. Most variants are benign. We present the case of a 75-year-old man with exertional dyspnea in whom the left anterior descending coronary artery arose from the right sinus of Valsalva, and the left circumflex coronary artery originated from the distal right coronary artery and supplied the obtuse marginal branch. No arteries originated from the left sinus of Valsalva. The patient was prescribed optimal medical therapy for atherosclerotic stenosis in his ramus intermedius. His symptoms were stable 3 years later.


2001 ◽  
Vol 11 (5) ◽  
pp. 568-570 ◽  
Author(s):  
Alessandro Giardini ◽  
Gaetano Gargiulo ◽  
Fernando M. Picchio

Anomalous origin of the left coronary artery from the pulmonary arteries is a rare and life-threatening defect, usually needing prompt surgical correction during infancy. We describe the case of a young asymptomatic patient with this defect who underwent surgical reimplantation despite the absence of signs of myocardial ischemia, due to the presence of proximal stenosis of the anomalous coronary artery.


2000 ◽  
Vol 34 (2) ◽  
pp. 145-154 ◽  
Author(s):  
M. C. Fernández ◽  
A. C. Durán ◽  
R. Real ◽  
D. López ◽  
B. Fernández ◽  
...  

In the Syrian hamster, anomalies in the origin of the left coronary artery are significantly associated with the bicuspid condition of the aortic valve. In this species, bicuspid aortic valves are expressions of a trait, the variation of which takes the form of a phenotypic continuum, ranging from a tricuspid aortic valve with no commissural fusion to a bicuspid aortic valve with the aortic sinuses located in ventrodorsal orientation and devoid of any raphe. The intermediate stages of the continuum are represented by tricuspid aortic valves with a more or less extensive fusion of the ventral commissure and bicuspid aortic valves with a more or less developed raphe located in the ventral aortic sinus. The present study was designed to decide whether there is a gap between tricuspid and bicuspid aortic valves regarding the incidence of coronary artery anomalies, or whether this incidence varies according to the different tricuspid and bicuspid morpho types of the continuum. The study was carried out in Syrian hamsters belonging to a single inbred family with a high incidence of tricuspid aortic valves with fusion of the ventral commissure, bicuspid aortic valves, and anomalies in the origin of the left coronary artery, i.e. single right coronary artery ostium in aorta, anomalous origin of the left coronary artery from the pulmonary artery, and anomalous origin of the left coronary artery from the dorsal aortic sinus. The specimens were examined by means of a stereomicroscope and, in several cases; scanning electron microscopy was also used. The relationships between anomalous coronary artery patterns and aortic valve morphologies were tested using a logistic regression model. The results obtained indicate that there is no discontinuity between tricuspid and bicuspid aortic valves regarding the incidence of coronary artery anomalies. The probability of occurrence of anomalous coronary artery patterns increases continuously according to the deviation degree of the aortic valve from its normal (tricuspid) design. The present findings suggest that in the Syrian hamster, the morphogenetic mechanisms involved in the formation of congenital anomalous aortic valves and anomalies in the origin of the left coronary artery, respectively, are strongly related from an aetiological viewpoint.


2012 ◽  
Vol 23 (3) ◽  
pp. 381-386 ◽  
Author(s):  
Giulia Tuo ◽  
Maurizio Marasini ◽  
Claudio Brunelli ◽  
Lucio Zannini ◽  
Manrico Balbi

AbstractObjectivesTo describe our experience in the management of coronary artery anomalies both in an adult and in a paediatric population and to compare the two groups for finding out differences in terms of angiographic incidence and treatment.Patients and methodsDatabases at the Department of Cardiology of San Martino Adult's Hospital and of Gaslini Children's Hospital were searched for all patients with a diagnosis of coronary artery anomaly who underwent coronary angiography between 1994 and 2006.ResultsCoronary anomalies were diagnosed in 76 (1%) adult patients. Anomalous left circumflex artery was the commonest coronary anomaly (25%). Anomalous left coronary artery from pulmonary artery and myocardial bridges were the only anomalies responsible for angina-like symptoms. No patients except the one with anomalous left coronary artery from pulmonary artery needed surgical intervention. In the paediatric population, we found 28 (0.9%) patients with coronary anomalies. Anomalous left coronary artery from pulmonary artery was the most common anomaly (48%) and always required emergency surgical treatment; in addition there were two patients with stenosis of the left main coronary artery.ConclusionCoronary artery anomalies may be associated with very acute, even life-threatening symptoms in children, whereas they are usually clinically silent and detected by accident on coronary angiography in adults. Recognition of coronary artery anomalies enables early treatment or close follow-up in children, whereas it could be useful in case of cardiac surgery in adults.


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