scholarly journals A case of hydrocephalus and meningoencephalocele in a rabbit, caused by aqueductal malformation

1974 ◽  
Vol 8 (2) ◽  
pp. 167-176 ◽  
Author(s):  
J. A. G. Geelen
Keyword(s):  
Cerebrospinal Fluid ◽  
Right Ventricle ◽  
Ependymal Cells ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation ◽  
Csf Pressure ◽  
Developmental Disturbance ◽  
The Right

The hydrocephalic brain of a 3-week-old rabbit with a meningoencephalocele is described. The hydrocephalus is caused by obstruction of cerebrospinal fluid circulation in the aqueduct, which is anomalously formed by several minute tubules surrounded by ectopic ependymal cells. The encephalocele is an atrophied part of the right ventricle forced out of the skull by increased CSF pressure. It is suggested that the aqueductal malformation is caused by an ependymal developmental disturbance.

scholarly journals The orthopedic characterization of cfap298tm304 mutants validate zebrafish to faithfully model human AIS

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marie-Hardy Laura ◽  
Cantaut-Belarif Yasmine ◽  
Pietton Raphaël ◽  
Slimani Lotfi ◽  
Pascal-Moussellard Hugues
Keyword(s):  
Cerebrospinal Fluid ◽  
Three Dimensional ◽  
Fluid Circulation ◽  
Micro Computed Tomography ◽  
Csf Flow ◽  
Cerebrospinal Fluid Circulation ◽  
Clinical Criteria ◽  
Brain And Spinal Cord ◽  
The Brain

AbstractCerebrospinal fluid (CSF) circulation relies on the beating of motile cilia projecting in the lumen of the brain and spinal cord cavities Mutations in genes involved in cilia motility disturb cerebrospinal fluid circulation and result in scoliosis-like deformities of the spine in juvenile zebrafish. However, these defects in spine alignment have not been validated with clinical criteria used to diagnose adolescent idiopathic scoliosis (AIS). The aim of this study was to describe, using orthopaedic criteria the spinal deformities of a zebrafish mutant model of AIS targeting a gene involved in cilia polarity and motility, cfap298tm304. The zebrafish mutant line cfap298tm304, exhibiting alteration of CSF flow due to defective cilia motility, was raised to the juvenile stage. The analysis of mutant animals was based on micro-computed tomography (micro-CT), which was conducted in a QUANTUM FX CALIPER, with a 59 µm-30 mm protocol. 63% of the cfap298tm304 zebrafish analyzed presented a three-dimensional deformity of the spine, that was evolutive during the juvenile phase, more frequent in females, with a right convexity, a rotational component and involving at least one dislocation. We confirm here that cfap298tm304 scoliotic individuals display a typical AIS phenotype, with orthopedic criteria mirroring patient’s diagnosis.

Experimental Studies Relating to Diagnostic Imaging in Disorders of Cerebrospinal Fluid Circulation

1980 ◽  
pp. 381-404 ◽  
Author(s):  
A. Everette James ◽  
Gary R. Novak ◽  
Ernst-Peter Strecker ◽  
Barry B. Burns ◽  
Francisco Correa-Paz ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Diagnostic Imaging ◽  
Experimental Studies ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation

scholarly journals Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate

Stroke ◽  
2017 ◽  
Vol 48 (8) ◽  
pp. 2301-2305 ◽  
Author(s):  
Romain Goulay ◽  
Julien Flament ◽  
Maxime Gauberti ◽  
Michael Naveau ◽  
Nolwenn Pasquet ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Nonhuman Primate ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation ◽  
Brain Parenchymal

The Trapped Temporal Horn

Neurosurgery ◽  
1979 ◽  
Vol 5 (2) ◽  
pp. 245-249 ◽  
Author(s):  
Harold Smith ◽  
Dixon Moody ◽  
Marshall Ball ◽  
Wayne Laster ◽  
David L. Kelly ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Right Ventricle ◽  
Brain Stem ◽  
Lateral Ventricle ◽  
Ventricular Wall ◽  
X Ray ◽  
Temporal Horn ◽  
Grade Ii ◽  
Computerized Cranial Tomography ◽  
The Right

Abstract Although the advent of computerized cranial tomography (CT) has decreased the number of pneumoencephalograms performed for the diagnosis of hydrocephalus and lesions of the posterior fossa, brain stem, and ventricles, there are some patients in whom pneumoencephalography should still be done because it adds valuable information to that obtained with CT. When the temporal horn becomes obstructed, the choroid plexus and ependymal surface “upstream” from the obstructing mass continue to produce cerebrospinal fluid (CSF). The temporal horn can thus enlarge enough to appear as a mass on CT because of its reduced x-ray attenuation coefficient. Pneumoencephalography is effective in this situation because air will flow past a mass that obstructs CSF and because the ventricular system dilates during pneumoencephalography. When pneumoencephalography is used in a patient with a trapped temporal horn, the partially trapped horn may enlarge approximately 24 hours later. With that precaution in mind, the neurosurgeon should find pneumoencephalography to be a useful adjunct to CT in delineating the cause of a trapped temporal horn. In the three patients reported here CT had indicated a unilateral trapped temporal horn; pneumoencephalography confirmed that finding and demonstrated both the location and the nature of the lesion. One patient had a Grade II astrocytoma fungating into the atrium of the right lateral ventricle, one had a mass extending into the right ventricle from the medial and superior ventricular wall with nodular encroachment on the ventricle, and one had a meningioma in the atrium of the right lateral ventricle.

Sign in / Sign up

Export Citation Format

Share Document