A meta-review using the ROBIS tool of effective doses in dental and maxillofacial cone beam CT
Objectives: To apply the ROBIS tool for assessment of risk of bias (RoB) in systematic reviews (SRs) in a meta-review on effective doses (EDs) in dental and maxillofacial cone beam CT. Methods: Three electronic databases and reference lists of included SRs were searched. Eligible SRs were classified as having low, high or unclear RoB. Findings of SRs were synthesised and data from primary studies combined to relate ED to field of view (FOV) and operating potential (kV). Results: Seven SRs were included: three displayed low RoB, three high and one had unclear RoB. Only one SR related ED to image quality. Deficiencies in reporting of eligibility criteria, study selection and synthesis of results in SRs were identified. Median ED for three FOV categories differed significantly (p < 0.001) but there was no significant difference in median ED between three operating potential groups. Conclusion: The ROBIS tool should have a role for meta-reviews of different aspects of radiology. The disappointing results for RoB might be remedied by developing standards to improve the quality of reporting of primary dosimetry studies and of SRs. There is a continuing need to perform dosimetry studies, although relating ED to image quality or diagnostic accuracy would add value. Advances in knowledge: This meta-review is the first in radiology to implement ROBIS to assess RoB in SRs of ED and identified that the trustworthiness of some SRs is questionable. The results underpin the importance of FOV dimensions as a determinant of ED in CBCT.