Magnetic resonance imaging in prostate cancer: the value of apparent diffusion coefficients for identifying malignant nodules

2007 ◽  
Vol 80 (950) ◽  
pp. 90-95 ◽  
Author(s):  
N M desouza ◽  
S A Reinsberg ◽  
E D Scurr ◽  
J M Brewster ◽  
G S Payne
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Diffusion Coefficients ◽  
Resonance Imaging ◽  
Apparent Diffusion Coefficients ◽  
Apparent Diffusion

scholarly journals Relationship between Gleason score and apparent diffusion coefficients of diffusion-weighted magnetic resonance imaging in prostate cancer patients

2016 ◽  
Vol 10 (11-12) ◽  
pp. 377 ◽  
Author(s):  
Tae Heon Kim ◽  
Chan Kyo Kim ◽  
Byung Kwan Park ◽  
Hwang Gyun Jeon ◽  
Byung Chang Jeong ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Gleason Score ◽  
Resonance Imaging ◽  
Characteristic Analysis ◽  
Adc Value ◽  
Cutoff Value ◽  
Apparent Diffusion Coefficients ◽  
Apparent Diffusion

Introduction: We assessed the correlation between the apparent diffusion coefficient (ADC) and pathological Gleason score (GS) of prostate cancer patients.Methods: A total of 125 patients who underwent multiparametric magnetic resonance imaging before radical prostatectomy for prostate cancer were included in this study. ADC values were compared with different GS. We used receiver operating characteristic analysis and determined the ADC cutoff value to differentiate tumours with a GS of 6 from those with a GS ≥7.Results: We identified 34 patients (27.2%) with a GS of 6; 33 patients (26.4%) with a GS of 7; 22 patients (17.6%) with a GS of 8; and 36 patients (28.8%) with a GS of ≥9. The mean ADC value for disease with a GS of 6 was 0.914 ± 0.161 x10-3 mm2/s; GS of 7: 0.741 ± 0.164 x10-3 mm2/s; GS of 8: 0.679 ± 0.130 x10-3 mm2/s; and GS of ≥9: 0.593 ± 0.089 x10-3 mm2/s. An ADC value of 0.830 ×10−3mm2/s was the best cutoff value to identify prostate cancer with a GS of 6.Conclusions: We observed an inverse relationship between GS and ADC value. Moreover, a cutoff ADC value may help differentiate disease with a GS of 6 from disease with a GS ≥7.

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