Application of Combined Test Index of Skin Temperature Changes after Total Knee Arthroplasty in Prediction and Early Detection of Knee Infection

2021 ◽  
Vol 11 (08) ◽  
pp. 3568-3573
Author(s):  
莲萍 蒋
Keyword(s):  
Total Knee Arthroplasty ◽  
Early Detection ◽  
Skin Temperature ◽  
Knee Arthroplasty ◽  
Temperature Changes ◽  
Knee Infection ◽  
Combined Test ◽  
Total Knee

scholarly journals Acute Infection in Total Knee Arthroplasty: Diagnosis and Treatment

2013 ◽  
Vol 7 (1) ◽  
pp. 197-204 ◽  
Author(s):  
Juan Carlos Martínez-Pastor ◽  
Francisco Maculé-Beneyto ◽  
Santiago Suso-Vergara
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Acute Infection ◽  
Septic Complication ◽  
Two Stage ◽  
Revision Process ◽  
Knee Infection ◽  
Prosthetic Knee ◽  
Total Knee ◽  
Prosthetic Knee Infection

Infection is one of the most serious complications after total knee arthroplasty (TKA). The current incidence of prosthetic knee infection is 1-3%, depending on the series.For treatment and control to be more cost effective, multidisciplinary groups made up of professionals from different specialities who can work together to eradicate these kinds of infections need to be assembled. About the microbiology,Staphylococcus aureusand coagulase-negative staphylococcus were among the most frequent microorganisms involved (74%).Anamnesis and clinical examination are of primary importance in order to determine whether the problem may point to a possible acute septic complication. The first diagnosis may then be supported by increased CRP and ESR levels. The surgical treatment for a chronic prosthetic knee infection has been perfectly defined and standardized, and consists in a two-stage implant revision process. In contrast, the treatment for acute prosthetic knee infection is currently under debate. Considering the different surgical techniques that already exist, surgical debridement with conservation of the prosthesis and polythene revision appears to be an attractive option for both surgeon and patient, as it is less aggressive than the two-stage revision process and has lower initial costs.The different results obtained from this technique, along with prognosis factors and conclusions to keep in mind when it is indicated for an acute prosthetic infection, whether post-operative or haematogenous, will be analysed by the authors.

scholarly journals Phage Therapy for Limb-threatening Prosthetic Knee Klebsiella pneumoniae Infection: Case Report and In Vitro Characterization of Anti-biofilm Activity

2020 ◽  
Author(s):  
Edison J Cano ◽  
Katherine M Caflisch ◽  
Paul L Bollyky ◽  
Jonas D Van Belleghem ◽  
Robin Patel ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Klebsiella Pneumoniae ◽  
Knee Arthroplasty ◽  
Phage Therapy ◽  
Knee Infection ◽  
Prosthetic Knee ◽  
Satisfactory Outcome ◽  
Total Knee ◽  
Prosthetic Knee Infection

Abstract Background Prosthetic joint infection (PJI) is a potentially limb-threatening complication of total knee arthroplasty. Phage therapy is a promising strategy to manage such infections including those involving antibiotic-resistant microbes, and to target microbial biofilms. Experience with phage therapy for infections associated with retained hardware is limited. A 62-year-old diabetic man with a history of right total knee arthroplasty 11 years prior who had suffered multiple episodes of prosthetic knee infection despite numerous surgeries and prolonged courses of antibiotics, with progressive clinical worsening and development of severe allergies to antibiotics, had been offered limb amputation for persistent right prosthetic knee infection due to Klebsiella pneumoniae complex. Intravenous phage therapy was initiated as a limb-salvaging intervention. Methods The patient received 40 intravenous doses of a single phage (KpJH46Φ2) targeting his bacterial isolate, alongside continued minocycline (which he had been receiving when he developed increasing pain, swelling, and erythema prior to initiation of phage therapy). Serial cytokine and biomarker measurements were performed before, during, and after treatment. The in vitro anti-biofilm activity of KpJH46Φ2, minocycline and the combination thereof was evaluated against a preformed biofilm of the patient’s isolate and determined by safranin staining. Results Phage therapy resulted in resolution of local symptoms and signs of infection and recovery of function. The patient did not experience treatment-related adverse effects and remained asymptomatic 34 weeks after completing treatment while still receiving minocycline. A trend in biofilm biomass reduction was noted 22 hours after exposure to KpJH46Φ2 (P = .063). The addition of phage was associated with a satisfactory outcome in this case of intractable biofilm-associated prosthetic knee infection. Pending further studies to assess its efficacy and safety, phage therapy holds promise for treatment of device-associated infections.

scholarly journals Temporal Change of Interleukin-6, C-Reactive Protein, and Skin Temperature after Total Knee Arthroplasty Using Triclosan-Coated Sutures

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Shih-Jie Lin ◽  
Fu-Chun Chang ◽  
Tsan-Wen Huang ◽  
Kuo-Ti Peng ◽  
Hsin Nung Shih ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Skin Temperature ◽  
Knee Arthroplasty ◽  
Surgical Site Infections ◽  
Control Group ◽  
Open Label ◽  
Local Skin ◽  
Systemic Complications ◽  
Functional Scores ◽  
Total Knee

The risk of surgical site infections (SSIs) after total knee arthroplasty (TKA) can never be eliminated. Antimicrobial sutures containing triclosan have been used to decrease SSIs, but whether triclosan-coated sutures are effective with TKA is unclear. Between 2011 and 2012, 102 patients randomly assigned to a triclosan or a control group were prospectively assessed. The incidence of SSI within 3 months of surgery, length of hospital stay, pain scale, functional scores, wound condition, and serum inflammatory markers during hospitalization and within 3 months postoperatively were compared. At the final follow-up, there were 2 patients with superficial infections (3.9%) in the control group but none in the triclosan group. Lower serum IL-6 was detected in the triclosan group at 4 weeks and 3 months. The local skin temperature of the knees—recorded at 3 months using infrared thermography—was lower in the triclosan group than in the control group. More precise analytical measurements are needed to investigate local and systemic complications, especially in the early subclinical stage. This prospective, randomized, open-label clinical trial is in the public registry: ClinicalTrials.gov (NCT02533492).

Acupuncture needle-associated prosthetic knee infection after total knee arthroplasty

2010 ◽  
Vol 20 (6) ◽  
pp. 627-631 ◽  
Author(s):  
Arata Nakajima ◽  
Ryutaku Kaneyama ◽  
Hitoshi Watanabe ◽  
Masazumi Murakami ◽  
Koichi Nakagawa ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Knee Infection ◽  
Acupuncture Needle ◽  
Prosthetic Knee ◽  
Total Knee ◽  
Prosthetic Knee Infection
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