scholarly journals Cytomorphological patterns of thyroid lesions among 1646 Sudanese patients: what we can learn from fine needle aspiration cytology retrospective analysis?

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 23
Author(s):  
Ali I. E. Osman ◽  
Ahmed O. Almobarak ◽  
Asma Kamalaldin Mohammed ◽  
Nouh S. Mohamed ◽  
Mohamed S. Muneer ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Follicular Adenoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Benign Thyroid ◽  
Thyroid Lesions

Introduction: Fine-needle aspiration (FNA) cytology biopsy of the thyroid gland is an accurate and useful diagnostic tool in the initial evaluation of nodular thyroid lesions. We aimed in this study to determine the cytomorphological patterns of thyroid lesions diagnosed by FNA among Sudanese patients. Methods: A descriptive retrospective, clinic-based study was performed. Cytopathological records of patients that attended the Total Lab Care Clinic in Khartoum-Sudan between January 2016 and December 2017 were reviewed. Results: A total of 1646 patients records were reviewed; 1385 (84.1%) were females and 261 (15.9%) males. A total of 1563 (94.9%) were negative for malignancy, 39 (2.4%) were positive for malignancy, 42 (2.6%) were indeterminate for malignancy and 2 (0.1%) were non-diagnostic. Colloid goiter was seen in 1147 patients (73.4%), benign hemorrhagic cysts were seen in 257, Hashimoto thyroiditis was seen in 77, benign thyroid nodules were seen in 76, keratocysts were seen in 2, thyroglossal duct cysts were seen in 2, thyroid follicular adenoma was seen in 1 and myxedema was seen in 1. For malignant patients; 11 had anaplastic thyroid cancer, 8 had papillary thyroid cancer, 7 had follicular thyroid cancer, 5 had metastatic thyroid cancer, 4 had medullary thyroid cancer, 3 had non-Hodgkin lymphoma and 1 had thyroid follicular adenoma. For those indeterminate for malignancy, 24 had follicular neoplasm and 18 had Hurthle cell neoplasm. Conclusions: Fine needle aspiration cytology for thyroid nodules provides a rapid and non-invasive technique for the evaluation and differentiation between benign and malignant lesions. This study also addresses the increased predominance of benign thyroid lesions among young patients and thyroid malignancy among the 4th decade of life.

scholarly journals Ultrasonographic characteristics as a criterion for repeat cytology in benign thyroid nodules

2010 ◽  
Vol 54 (1) ◽  
pp. 52-55 ◽  
Author(s):  
Pedro Weslley Rosário ◽  
Saulo Purisch
Keyword(s):  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Cytological Diagnosis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

OBJECTIVE: To report the results of repeat fine-needle aspiration cytology (FNAC) in thyroid nodules with an initial benign cytological diagnosis that grow during follow-up and/or present suspicious ultrasonographic characteristics. SUBJECTS AND METHODS: The sample consisted of 456 patients with 895 nodules. FNAC was repeated after 12 to 18 months in the case of nodules with suspicious ultrasonographic characteristics, irrespective of growth, and when the nodules showed significant growth. RESULTS: Among the 895 nodules examined, 102 (11.4%) presented suspicious ultrasonographic characteristics. The second FNAC revealed malignancy in 18 (17.6%) nodules, including 20% (2/10) of those showing growth and 17.4% (16/92) that did not. Seventy-six (9.6%) of 793 nodules without suspicious characteristics presented growth. Only one case (1.3%) of malignancy was diagnosed by repeat FNAC. CONCLUSIONS: The study suggests ultrasonographic characteristics rather than growth as a criterion for repeat FNAC in the case of nodules with an initial benign cytological diagnosis.

Thyroid Cancer in the Thyroid Nodules Evaluated by Ultrasonography and Fine-Needle Aspiration Cytology

Thyroid ◽  
2005 ◽  
Vol 15 (7) ◽  
pp. 708-717 ◽  
Author(s):  
Jen-Der Lin ◽  
Tzu-Chieh Chao ◽  
Bie-Yu Huang ◽  
Szu-Tah Chen ◽  
Hung-Yu Chang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

scholarly journals Correlation between fine needle aspiration cytology and histopathological examination in thyroid swellings-a pilot study

2020 ◽  
Vol 7 (11) ◽  
pp. 4381
Author(s):  
Sanjay V. Gupta ◽  
Manish Munjal ◽  
Devyani Gupta ◽  
Siddharth Gupta ◽  
Shubham Munjal ◽  
...  
Keyword(s):  
Papillary Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Nodules ◽  
Follicular Adenoma ◽  
Follicular Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Thyroid swellings are an enigma that necessitates either, a partial thyroidectomy and a tissue diagnosis to be followed by completion surgery or straightaway a radical intervention. A preoperative presumptive diagnosis of a thyroid swelling, solitary or otherwise is correlated with the post-surgical histopathological finding in the present study.Methods: 30 patients of thyroid nodules were selected from the head-neck tumour clinic of Dayanand medical college hospital, Ludhiana. Pre-operative fine needle aspiration cytology (FNAC) was performed and subjects taken for thyroidectomy, partial or total as the case maybe.Results: There were 20 (66.6%) females in the age group 25-65 years and 10 males (33.3%) 19-50 years with thyroid nodules. 86.6%, 26 patients were of follicular adenoma, 10% 3 patients of papillary carcinoma and 3.33% 1 patient of follicular carcinoma. No case in this study was reported as medullary carcinoma. In the cytological diagnosis of follicular neoplasm in 5 cases, 3 were diagnosed as thyroid adenoma, 2 were finally found to be papillary carcinoma. Overall sensitivity of fine needle aspiration was 40%. There was 84.6% agreement in follicular adenoma; 33% in papillary carcinoma and 100% in follicular carcinoma, and overall accuracy was 85.7%.Conclusion: FNAC is an ideal preoperative investigative modality in thyroid swellings with overall accuracy of 85 % and can differentiate preoperatively a benign from a   malignant thyromegaly; and thereby plan extent of surgery, with or without a neck dissection, Maximum cases of follicular adenoma could be easily diagnosed with this aspiration modality.                                               

scholarly journals Correlation between Ultrasonography and Fine Needle Aspiration Cytology (FNAC) Findings in Patients with Thyroid Lesions

2021 ◽  
Vol 5 (8) ◽  
Author(s):  
Asraf Hussain ◽  
Kalim Akhtar
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Thyroid Disorders ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Benign Thyroid ◽  
Thyroid Lesions

Background:Thyroid nodules are common presentation in patients having thyroid disorders. There is approximately 4-5% incidence of clinically apparent thyroid lesions in general populations.Thyroid nodules are about four times more common in females than in males. The present study aims to diagnose the thyroid lesions and evaluate to relation and diagnostic test of ultrasonography (USG) and Fine Needle Aspiration Cytology (FNAC) report. To determine the sensitivity of ultrasonography in detecting thyroid lesions.Method:This was hospital based prospective study carried in 94 patients who came to radiology department for USG neck, after clinical examination frommedicine, surgery and ENT department.Those patients with thyroid lesions were followed and advised for USG guided FNAC of thyroid swelling. The patients who were advised for FNAC, and gave consent for procedure were included in the study. The USG guided FNAC was done and wasfurther evaluated by pathologist. Results:Out of 94 cases, 85 were benign nodules and 9 were malignant nodules by USG which were further confirmed by FNAC with results of 87 benign and 7 malignant.The USG diagnosed the benign thyroid nodule with sensitivity of 96.55% and specificity of 85.71%, positive predictive value 98.82%, negative predictive value 66.67%, accuracy 95.74%. The result revealed that there is a strong relation between diagnoses of benign thyroid lesions by USG and final diagnosis by FNAC (P=0.001).Conclusion:High resolution grey scale imaging features can differentiate benign and malignant lesions. USG is very helpful for FNAC, characterization of nodules and provides differential diagnosis in those patients affecting with thyroid disorders.

scholarly journals Diagnostic accuracy of ultrasonography versus fine-needle-aspiration cytology for predicting benign thyroid lesions

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Sultan Abdulwadoud Alshoabi ◽  
Abdulkhaleq Ayedh Binnuhaid
Keyword(s):  
Diagnostic Accuracy ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
The Us ◽  
Needle Aspiration Cytology ◽  
Benign Thyroid ◽  
Thyroid Lesions

Background and Objective: Thyroid nodules (TNs) are abnormal growths of thyroid cells that form masses within the thyroid gland. TNs are common, and the importance lies in need to exclude thyroid cancer. This study was intended to evaluate the diagnostic accuracy of ultrasonography for differentiating benign from malignant thyroid lesions in comparison with fine-needle aspiration cytology (FNA cytology). Methods: This study involved 133 patients with thyroid lesions. All patients underwent thyroid ultrasonography and ultrasound (US)-guided-FNA cytology and results were compared. Results: Out of 133 patients included in this study, the mean age was 41.2±15 years, and 113 (85%) were female. Thyroid lesions were benign in 126 cases (94.7%) and malignant in nine cases (5.3%). Among 124 patients with thyroid lesions diagnosed as benign with US, 122 (98.38%) were confirmed to be benign with FNA cytology, and only 2 (1.6%) were proved to be malignant. Among nine patients with thyroid lesions diagnosed as malignant by US, 5 (55.6%) were confirmed to be malignant by FNA cytology, and 4 (44.4%) were proved to be benign. The US diagnosed benign thyroid lesions with a sensitivity, specificity, positive predictive value, and negative predictive value of 98.38%, 71.42%, 98.38%, and 55.55%, respectively. The results revealed strong compatibility between diagnosis of benign thyroid lesions by the US and proved diagnosis by FNA cytology (p<0.001). Conclusion: B-mode ultrasonography is a valuable tool in differentiating benign from malignant thyroid lesions. It can almost always predict the benign nature of thyroid lesions with excellent diagnostic accuracy. doi: https://doi.org/10.12669/pjms.35.3.292 How to cite this:Alshoabi SA, Binnuhaid AA. Diagnostic accuracy of ultrasonography versus fine-needle-aspiration cytology for predicting benign thyroid lesions. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.292 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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