Case Report: Transient cortical blindness following coronary angiography

Temporary blindness, also known as transient cortical blindness, is an uncommon impediment of contrast agent usage during angiography procedures. The occurrence of blindness after a cardiac catheterization procedure is rare and its pathophysiology remains largely speculative. The most probable mechanism seems to be contrast agent-related disruption of the blood–brain barrier, possibly initiated by several predisposing factors. This case reports a 52-year-old man with transient vision loss that occurred following coronary angiography. Brain magnetic resonance imaging (MRI) showed no acute pathology and his vision spontaneously returned within approximately 15 hours post-procedure without any requirement of specific therapy. Suggesting that transient cortical blindness may have occurred following coronary angiography which subsequently self-resolved.

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Transient cortical blindness after coronary angiography

The Lancet ◽

10.1016/s0140-6736(05)78906-6 ◽

1998 ◽

Vol 351 (9114) ◽

pp. 1513-1514 ◽

Cited By ~ 3

Author(s):

Judith Hinchey ◽

Patrick J Sweeney

Keyword(s):

Coronary Angiography ◽

Cortical Blindness ◽

Transient Cortical Blindness

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De novo convulsive status epilepticus in patients with multiple sclerosis treated with dalfampridine

Multiple Sclerosis Journal ◽

10.1177/1352458518790379 ◽

2018 ◽

Vol 25 (4) ◽

pp. 618-621 ◽

Cited By ~ 3

Author(s):

Emilie Panicucci ◽

Mikael Cohen ◽

Veronique Bourg ◽

Fanny Rocher ◽

Pierre Thomas ◽

...

Keyword(s):

Multiple Sclerosis ◽

Status Epilepticus ◽

De Novo ◽

Case Reports ◽

Brain Magnetic Resonance Imaging ◽

Convulsive Status Epilepticus ◽

Biological Tests ◽

History Of ◽

Magnetic Resonance Imaging Mri ◽

History Of Epilepsy

Background: Dalfampridine extended release (DAL) is a broad-spectrum voltage-gated potassium channel blocker that is indicated in multiple sclerosis to improve the nerve conduction of demyelinated axons. Seizures are a known side effect of DAL, which is contraindicated in patients with a history of epilepsy. Objective: Three cases of multiple sclerosis (MS) with de novo convulsive status epilepticus (CSE) probably related to dalfampridine administration are described. Methods: No patients had a history of seizures or renal impairment. Biological tests were normal. A brain magnetic resonance imaging (MRI) showed diffuse cortical and subcortical atrophy without active inflammatory lesions. Results: All three patients presented with CSE that was attributed to DAL and so was discontinued. Conclusion: These case reports illustrate that, aside from seizures, de novo CSE is a potential complication of MS patients treated with DAL.

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Transient Cortical Blindness after Coronary Angiography

Journal of International Medical Research ◽

10.1177/147323000903700433 ◽

2009 ◽

Vol 37 (4) ◽

pp. 1246-1251 ◽

Cited By ~ 9

Author(s):

BN Alp ◽

N Bozbuğa ◽

MA Tuncer ◽

C Yakut

Keyword(s):

Coronary Angiography ◽

Cerebral Haemorrhage ◽

Cortical Blindness ◽

Focal Neurological Deficit ◽

Computed Tomographic ◽

Contrast Enhanced ◽

Computed Tomographic Scan ◽

Transient Cortical Blindness ◽

Occipital Lobes ◽

The Brain

Transient cortical blindness is rarely encountered after angiography of native coronary arteries or bypass grafts. This paper reports a case of transient cortical blindness that occurred 72 h after coronary angiography in a 56-year old patient. This was the patient's fourth exposure to contrast medium. Neurological examination demonstrated cortical blindness and the absence of any focal neurological deficit. A non-contrast-enhanced computed tomographic scan of the brain revealed bilateral contrast enhancement in the occipital lobes and no evidence of cerebral haemorrhage, and magnetic resonance imaging of the brain showed no pathology. Sight returned spontaneously within 4 days and his vision gradually improved. A search of the current literature for reported cases of transient cortical blindness suggested that this is a rarely encountered complication of coronary angiography.

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Transient cortical blindness related to coronary angiography and graft study

The Medical Journal of Australia ◽

10.5694/j.1326-5377.2002.tb04636.x ◽

2002 ◽

Vol 177 (1) ◽

pp. 43-44 ◽

Cited By ~ 12

Author(s):

Kiam K Lim ◽

Dorothy J Radford

Keyword(s):

Coronary Angiography ◽

Cortical Blindness ◽

Transient Cortical Blindness

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030 Transient cortical blindness after coronary angiography: 2 cases report

Archives of Cardiovascular Diseases Supplements ◽

10.1016/s1878-6480(11)70032-5 ◽

2011 ◽

Vol 3 (1) ◽

pp. 10

Author(s):

Marie Solange Ndom ◽

Najat Mouine

Keyword(s):

Coronary Angiography ◽

Cortical Blindness ◽

Transient Cortical Blindness

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Transient Edematous Lesions of the Splenium in Epileptic Patients

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100004261 ◽

2005 ◽

Vol 32 (3) ◽

pp. 352-355 ◽

Cited By ~ 9

Author(s):

Giovanna Carrara ◽

Edoardo Ferlazzo ◽

Donatella Tampieri ◽

Frederick Andermann ◽

Denis Melanson

Keyword(s):

Antiepileptic Drugs ◽

Case Reports ◽

Brain Mri ◽

Brain Magnetic Resonance Imaging ◽

High Signal ◽

Focal Lesions ◽

Epileptic Patients ◽

Magnetic Resonance Imaging Mri ◽

Patients With Epilepsy

ABSTRACT:Background:Transient focal lesions in the splenium of the corpus callosum (SCC) have been previously described in patients with epilepsy or without epilepsy but receiving antiepileptic drugs (AED).Case reports:Two epileptic patients were admitted to our long-term monitoring unit. Antiepileptic drugs were completely discontinued a few days later. One patient had no seizures. The other had three attacks, the last of which occurred two days before a brain magnetic resonance imaging (MRI) was performed. In both cases brain MRI showed a lesion in the SCC characterized by high signal on T2-weighted images and no enhancement after Gadolinium infusion. The patients were discharged with their pre-admission medications. A follow-up MRI five weeks later showed resolution of the SCC lesions.Conclusions:The pathogenesis of transient SCC lesions in epileptic patients is still unclear. In our patients, either the sudden AED withdrawal or the seizures activity may be presumed to be the cause, though an individual susceptibility must also be considered.

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