scholarly journals Case Report: Challenges on diagnosis and therapy of malignant adrenal oncocytic neoplasm

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 882
Author(s):  
Agus Rizal Ardy Harlandy Hamid ◽  
Sahat Matondang ◽  
Agnes Stephanie Harahap ◽  
Ivan Putrantyo
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Adrenal Tumors ◽  
Case Presentation ◽  
Tumor Bed ◽  
Abdominal Ct Scan ◽  
History Of ◽  
Adrenal Masses ◽  
The Right ◽  
Oncocytic Neoplasm

Background: Adrenal masses are common incidental findings, most of which are benign and non-functional. Malignant adrenal tumors, however, differ from their benign counterpart and confer poor prognosis. In addition, the oncocytic variants of these tumors present challenges to clinicians owing to their unique biologic behavior and rarity. Case presentation: We present a case report of a 61-year-old male with a T2N0M0 adrenocortical oncocytic neoplasm of the right adrenal gland. The patient complained of worsening right upper quadrant abdominal pain and was diagnosed with a right adrenal mass after an abdominal CT-scan examination two weeks before. Subsequently, the patient underwent open adrenalectomy due to a history of abdominal surgery. Due to unique oncocytic biologic behavior, we used the Lin–Weiss–Bisceglia criteria to predict a malignancy instead of the Weiss system. We only found one malignant criterion, which showed a small tumor invasion on the vascular bed on one histopathological section. Thus, we diagnosed it as malignant adrenocortical oncocytic neoplasm. Furthermore, the PET Scan showed no residual mass or pathological metabolic activity on the tumor bed and metastatic sign. Conclusions: The diagnosis of the malignant oncocytic adrenal case is based on the histopathological criteria. Based on this case, we suggest a thorough histopathological examination to determine malignant criteria in adrenal neoplasm cases.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

scholarly journals Primary leiomyoma of the ureter: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Shingo Morinaga ◽  
Shigeyuki Aoki ◽  
Motoi Tobiume ◽  
Genya Nishikawa ◽  
Hiroyuki Muramatsu ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Histopathological Examination ◽  
Urine Cytology ◽  
Benign Tumors ◽  
Case Presentation ◽  
Old Japanese ◽  
Retrograde Pyelogram ◽  
History Of ◽  
The Right ◽  
Enhanced Computed Tomography

Abstract Background Only 14 cases of leiomyoma with ureteral origin have been reported previously. Such primary leiomyomas often present as hydronephrosis, making the diagnosis difficult. Radical nephroureterectomy is often performed because of the possible diagnosis of a malignant tumor. We report the 15th case of primary leiomyoma with a ureteral origin. Case presentation A 51-year-old Japanese man presented with a chief complaint of asymptomatic gross hematuria with a history of hypertension. Enhanced computed tomography showed a tumor at the upper part of the right ureter that appeared to be the cause of hydronephrosis and contracted kidney; no retroperitoneal lymphadenopathy and distal metastasis were observed. A well-defined 20-mm (diameter) defect was identified at the upper of the right ureter on retrograde pyelogram with no bladder cancer on cystoscopy. Urine cytology and right divided renal urine cytology findings were negative. Laparoscopic nephroureterectomy was performed, and the extracted tumor measured 20 × 13 mm. Histopathological examination revealed primary leiomyoma with no recurrence 16 months after the operation. Conclusions Preoperative examination with the latest available ureteroscopic technology can help preserve renal function in the case of benign tumors by enabling preoperative ureteroscopic biopsy or intraoperative rapid resection. Moreover, nephroureterectomy is recommended in the case of preoperative suspicion of ureteral malignant tumors.

scholarly journals Benign Pleural Multicystic Mesothelioma: A Rare Case Report

2021 ◽  
Author(s):  
Alireza Rezvani ◽  
SeyedehMaryam Pishva ◽  
Amirhossein Erfani ◽  
Ahmad Monabati ◽  
Bizhan Ziaian ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Cough ◽  
Rare Case ◽  
Pleural Mesothelioma ◽  
Case Presentation ◽  
Rare Case Report ◽  
History Of ◽  
The Right ◽  
Lateral Thoracotomy ◽  
Pleural Involvement

Abstract Background: Fewer than 200 benign multicystic peritoneal mesothelioma cases were reported worldwide till 2017, while its pleural involvement has rarely been reported. Case presentation: We report a 70-year-old man who presented with three months history of chronic cough. Surgical resection was performed, and the pathology confirmed benign multicystic pleural mesothelioma. The patient underwent right lateral thoracotomy, wedges resection of the right upper lobe, and parietal pleurectomy and was discharged with an uneventful postop course.Conclusion: Based on published literature to date, this is the second reported case of pleural involvement of this disease.

scholarly journals A case report of exophytic nasal papilloma with acute dacryocystitis as the first symptom

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ya Mo ◽  
Danning Long ◽  
Luoxiang Li ◽  
Yanlin Zheng
Keyword(s):  
Case Report ◽  
General Anesthesia ◽  
Malignant Transformation ◽  
Benign Tumor ◽  
Clinical Observation ◽  
Purulent Discharge ◽  
Lacrimal Sac ◽  
Case Presentation ◽  
History Of ◽  
The Right

Abstract Background This study aims to explore a case of exophytic nasal papilloma with acute dacryocystitis as the first symptom. Case presentation A 72-year-old male patient complaining of “a 10-year history of tearing and purulent discharge from the right eye, with subsequent redness and pain in the inner canthus for three days” was initially diagnosed with acute dacryocystitis of the right eye. The patient was treated with anti-inflammatory therapy. However, the redness and swelling of the inner canthus continued to increase. An endoscopic dacryocystorhinostomy of the right eye was performed under general anesthesia. A large amount of purulent secretion was drained during the operation. As a result, the swelling of the inner canthus was significantly reduced. A routine intra-operative biopsy of the wall of the lacrimal sac revealed an exophytic nasal papilloma. A second biopsy, 1 week after the surgery, revealed the same result. The patient was advised to undergo a dacryocystectomy once the swelling had subsided. However, the patient was reluctant to undergo this surgery and remains under clinical observation. Conclusion It is rare for an exophytic nasal papilloma, which is a benign tumor in the lacrimal sac, which has the potential for recurrence and malignant transformation, to manifest with acute dacryocystitis as the first symptom. Therefore, this case report could provide a reference for the future clinical diagnosis of this disease.

scholarly journals Subcutaneous hyalohyphomycosis caused by Acremonium recifei: case report

1995 ◽  
Vol 37 (3) ◽  
pp. 267-270 ◽  
Author(s):  
Clarisse Zaitz ◽  
Edward Porto ◽  
Elisabeth Maria Heins-Vaccari ◽  
Aya Sadahiro ◽  
Ligia Rangel Barbosa Ruiz ◽  
...  
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Histopathological Examination ◽  
Traumatic Injury ◽  
The State ◽  
Right Hand ◽  
History Of ◽  
The Right ◽  
First Time ◽  
Hematoxylin Eosin

We present a case of subcutaneous hyalohyphomycosis due to Acremonium recifei, a species whose habitat is probably the soil, first identified in 1934 by Arêa Leão and Lobo in a case of podal eumycetoma with white-yellowish grains and initially named Cephalosporium recifei. A white immunocompetent female patient from the state of Bahia, Brazil, with a history of traumatic injury to the right hand is reported. The lesion was painless, with edema, inflammation and the presence of fistulae. Seropurulent secretion with the absence of grains was present. Histopathological examination of material stained with hematoxylin-eosin showed hyaline septate hyphae. A culture was positive for Acremonium recifei. Treatment with itraconazole, 200 mg/day, for two months led to a favorable course and cure of the process. We report for the first time in the literature a case of subcutaneous hyalohyphomycosis due to Acremonium recifei in a immunocompetent woman. Treatment with itraconazole 200 mg/day, for two months, resulted in cure.

scholarly journals Vulvar Pyogenic Granuloma in a Postmenopausal Woman: Case Report and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Deniz Cemgil Arikan ◽  
Gurkan Kiran ◽  
Hamide Sayar ◽  
Bulent Kostu ◽  
Ayhan Coskun ◽  
...  
Keyword(s):  
Postmenopausal Woman ◽  
Histopathological Examination ◽  
Single Layer ◽  
Pyogenic Granuloma ◽  
Case Presentation ◽  
First Case ◽  
History Of ◽  
Foul Smell ◽  
Vascular Channels ◽  
The Right

Introduction. Although pyogenic granulomas (PG) are common and benign vascular proliferations of the skin and mucous membranes, they are relatively rare on the vulva.Case Presentation. A 57-year-old G7P7 postmenopausal woman presented with a 3-year history of a foul smell and bleeding lesions in the genital region. A gynecologic examination revealed multiple large papillomatous, pedunculated, and lobulated lesions that were cherry-red and infective in appearance. There was a 2-cm lesion at the upper intersection of the labia majora, a 2-cm lesion on the right labium majus, and a 4-cm lesion on the clitoris. The patient complained of itching, and the lesions were asymptomatic, except for occasional bleeding. All lesions were excised and sent for histopathological examination, which revealed an ulcerated polypoidal structure with extensive proliferation of vascular channels lined by a single layer of endothelium. The histopathological features were consistent with PG.Conclusion. The present case is the first case of multiple pyogenic granulomas on the vulva in a postmenopausal woman.

scholarly journals Subhepatic appendix: an ectopic topography not to be disregarded: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Abdoul Kadir Ibrahim Mamadou ◽  
Souleymane Mounkaila ◽  
Nouhou Hama Aghali ◽  
Mahaman Laouali Harouna Amadou ◽  
Ousseini Adakal
Keyword(s):  
Elderly Patient ◽  
Peptic Ulcer ◽  
Abdominal Pain ◽  
Case Report ◽  
Surgical Intervention ◽  
Quadrant Pain ◽  
Case Presentation ◽  
Perforated Appendix ◽  
History Of ◽  
The Right

Abstract Introduction Subhepatic appendix is most often due to an anomaly of rotation of the primary intestine occurring during embryogenesis. This ectopic topography associated with advanced age can be a serious diagnosis problem at the stage of appendicitis or appendicular peritonitis. Case presentation We report the case of a 60-year-old melanoderm man, with a history of urinary pathology and peptic ulcer, referred from a health district for abdominal pain of the right hypochondrium evolving for about 5 days, secondarily generalized, in whom we suspected peritonitis, the etiology of which remains to be determined. During the surgical intervention, after preoperative resuscitations measures, a phlegmonous perforated appendix was found under the liver. No postoperative complication was noted, and he was discharged home 8 days after his operation. Conclusion Subhepatic appendicular peritonitis occurring in an elderly patient poses enormous diagnostic problems. When faced with right upper quadrant pain, considering acute ectopic appendicitis would significantly reduce complications.

scholarly journals Reduction en masse of inguinal hernia after self-reduction: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Khosrow Najjari ◽  
Hossein zabihi Mahmoudabadi ◽  
Seyed Zeynab Seyedjavadeyn ◽  
Reza Hajebi
Keyword(s):  
Case Report ◽  
Inguinal Hernia ◽  
Ct Scan ◽  
Lower Quadrant ◽  
Case Presentation ◽  
Delay In Diagnosis ◽  
Patient Reported ◽  
History Of ◽  
Old Persian ◽  
The Right

Abstract Background Reduction en mass (REM) is one of the rare complications of inguinal hernia reduction. Although REM can be detected on the basis of specific computed tomography (CT) scan findings, many radiologists are not familiar with its radiological appearance because of the scarcity of this complication, which may cause a delay in diagnosis. Case presentation The patient reported in this article was a 50-year-old Persian man with a history of inguinal hernia, who had been referred with the periumbilical pain that radiated to the right lower quadrant and developed following hernia replacement by the patient himself. REM diagnosis was based on clinical examination and CT scan findings, and surgical treatment was performed by the Lichtenstein repair and mesh implantation. Conclusions Although REM usually occurs after reduction with compression in the inguinal hernia, this unique case report highlighted the possibility of REM after self-reduction. Surgeons and radiologists should consider REM in patients with a history of inguinal hernia presenting with intestinal obstruction symptoms, even without any apparent signs of hernia in the physical examination.

scholarly journals A case report describing a rare presentation of Acute Inflammatory Demyelinating Polyradiculopathy (AIDP)

2020 ◽  
Vol 4 (4) ◽  
pp. 01-02
Author(s):  
Parvathy Sankar
Keyword(s):  
Case Report ◽  
Taste Sensation ◽  
Rare Presentation ◽  
Fisher Syndrome ◽  
Lower Extremity Weakness ◽  
Lower Face ◽  
Case Presentation ◽  
Upper And Lower Extremities ◽  
History Of ◽  
The Right

Background: AIDP (Acute Inflammatory Demyelinating Polyradiculopathy) commonly presents as bilateral lower extremity weakness and areflexia with albuminocytologic dissociation on CSF findings. Sensory symptoms are not prominent presenting features in patients. However, Bulbar and Miller Fisher variants of AIDP are very rare. This case report highlights the unique presentation where unilateral facial nerve palsy along with perioral numbness and decreases taste sensation was the presenting symptom. Case presentation: A 33-year-old male with a past medical history of rhabdomyosarcoma s/p resection who presented with the chief complaint of numbness and dysphagia. He developed left-sided facial droop and decreased taste sensation following an episode of bronchitis six weeks ago. Pertinent positives include mild dysphagia, decreased appetite, congestion and rhinorrhea. Physical exam was not significant except for decreased sensation of the upper and lower left face, decreased sensation of the right lower face, decreased light touch of the right upper extremity, 3+ reflexes of both upper and lower extremities bilaterally. Conclusions: This case report highlights the unique presentation of Bulbar AIDP with some symptoms of Miller Fisher syndrome. Predominant sensory symptoms such as perioral numbness and decreased taste sensation might be the predominant symptoms that bring the patient to attention. Hence, it is imperative to perform a lumbar puncture to support the diagnosis of variant AIDP when prominent sensory symptoms are present.

scholarly journals Epibulbar complex choristoma with simultaneous involvement of eyelid: a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yun Hsia ◽  
Huang-Chun Lien ◽  
I-Jong Wang ◽  
Shu-Lang Liao ◽  
Yi-Hsuan Wei
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Atypical Presentation ◽  
Fundus Examination ◽  
Upper Eyelid ◽  
Case Presentation ◽  
Ectopic Cilia ◽  
The Right ◽  
Nevus Sebaceous

Abstract Background Epibulbar complex choristoma, a rare congenital epibulbar tumor, has many diverse forms. Reviewing the literature, it can present clinically as either a circumferential or isolated epibulbar mass, limbal tumor, lateral canthal mass, aggregate of ectopic cilia in the upper eyelid, eyelid mass mimicking chalazion, or lacrimal caruncle mass. The management depends on the extent of involvement, the risk of amblyopia, and cosmetic concerns. Here, we report an atypical presentation of epibulbar complex choristoma with simultaneous eyelid involvement. Case presentation A 1-month-old full-term boy was brought to our clinic with congenital epibulbar mass of the right eye with simultaneous eyelid involvement. Dilated fundus examination was unremarkable. Survey for linear nevus sebaceous Jadassohn was negative. Due to concerns of possible amblyopia and cosmetics, lamellar keratectomy, sclerotomy, and conjunctivoplasty were performed to remove the epibulbar lesion. The eyelid defect was reconstructed with 6–0 Vicryl sutures. Histopathological examination reported complex choristoma. Upon three-year follow-up, low astigmatism and favorable cosmetics results were achieved. Conclusions Congenital complex choristoma can present clinically as an epibulbar mass with eyelid involvement. The management depends on the extent of involvement, the risk of amblyopia, and cosmetic concerns. The method of eyelid reconstruction should be tailored according to the residual eyelid defect.

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