scholarly journals The effect of diet on nucleic acid metabolism of skeletal muscle. VI. The effect of protein deprivation on the amounts of soluble and ribosomal RNA in rat skeletal muscle.

1975 ◽  
Vol 39 (4) ◽  
pp. 753-758
Author(s):  
Yoko SAITO ◽  
Makoto KANDATSU
1968 ◽  
Vol 107 (3) ◽  
pp. 361-366 ◽  
Author(s):  
B. I. Sahai Srivastava ◽  
Roger K. Atkin

1. Changes in nucleic acid metabolism in first seedling leaves of barley plants during aging (from 7 to 27 days) were followed, and the effect of continual removal of the second leaf and basal meristem or of treating the first leaf with 20p.p.m. kinetin on these changes was examined. During aging of the first seedling leaves the ribosomal RNA, DNA and soluble RNA declined, with ribosomal RNA showing the most rapid fall. This was, however, accompanied by increased incorporation of 32P into RNA, which reached its peak on the fifteenth day. 2. Second-leaf removal partially suppressed first-leaf senescence as judged by retarded chlorophyll and nucleic acid decline and by a decreased extent of RNA labelling. Treatment with kinetin, however, did not prove effective. 3. No significant differences in the sucrose-gradient pattern of 32P-labelled nucleic acids or in the 32P-labelled nucleotide composition of RNA fractions during aging or during the two treatments were noted, except for a decrease in CMP content of soluble RNA during aging. 4. The results demonstrate that important changes in RNA metabolism are associated with leaf senescence.


1971 ◽  
Vol 51 (2) ◽  
pp. 265-270 ◽  
Author(s):  
A. A. SIMPSON ◽  
G. H. SCHMIDT

SUMMARY Lactogenesis was initiated by intraductal injection of prolactin into individual lobes of rabbit mammary glands previously developed by injections of oestrogen and progesterone. Nucleic acid metabolism was assessed at various times after prolactin treatment. A systemic pulse of [3H]thymidine or [3H]uridine was used to determine the specific effects of prolactin treatment on RNA and DNA synthesis and metabolism. Prolactin increased the rate of RNA synthesis. It is suggested that prolactin enhanced both the rate of RNA movement from the nucleus, and its rate of metabolism in the cytoplasm. The greatest increase in the rate of synthesis occurred in non-ribosomal RNA. Subsequent to its effect on RNA, prolactin enhanced DNA synthesis. Total RNA per cell increased as indicated by an increased RNA:DNA ratio. These changes are considered to be specifically due to the local action of prolactin.


1963 ◽  
Vol 9 (3) ◽  
pp. 337-341 ◽  
Author(s):  
MICHIO OISHI ◽  
SHIGERU KITAYAMA ◽  
HAJIME TAKAHASHI ◽  
BUNJI MARUO

1968 ◽  
Vol 259 (2) ◽  
pp. 186-188 ◽  
Author(s):  
D. Neubert ◽  
E. Oberdisse ◽  
H.-J. Merker ◽  
E. K�hler ◽  
B.-R. Balda

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