Vaccination against COVID-19 in Poland

Introduction. Due to the still difficult and worsening epidemic situation in Poland, related to the second wave of the coronavirus pandemic (COVID-19), it turned out to be necessary to develop, prepare and conduct additional training on the work of medical personnel during the pandemic. Preventive vaccinations and their skilful implementation play a very important role.Aim. The aim of the systematic review is to present the general principles, procedures and competences of nurses in the pandemic era, this work can be used to conduct a comparative meta-analysis.Disscusion. The vaccine protects against the symptoms of COVID-19, which has been proven in clinical trials. For both the Comirnaty vaccine and the Moderna vaccine, the European Medicines Agency website states that the effect of vaccination on the transmission of the virus is unknown and whether vaccinated people can transmit SARS-CoV-2. Clinical trials are scheduled for 2 years and, as part of conditional approval, companies will complete the data after subsequent periodic evaluations.Conclusion. Over 1.5 million people worldwide have died since the outbreak of the COVID-19 epidemic. Each vaccinated person is potentially from a few to a dozen or so people protected against infection. Already 50% of the vaccinated population will significantly reduce the risk of spreading the coronavirus in it. Vaccines are the most effective method of protection against infection with various diseases. Humanity has been successfully using this achievement of civilization for several hundred years.

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Abstract #273: Benefits of Extended Release Metformin: Systematic Review of the Ongoing Clinical Trials

Endocrine Practice ◽

10.1016/s1530-891x(20)44981-x ◽

2016 ◽

Vol 22 ◽

pp. 69

Author(s):

Hemant Thacker ◽

Rajeev Chawla ◽

Navneet Agrawal ◽

Rohit Kapoor ◽

Noel Somasundaram ◽

...

Keyword(s):

Systematic Review ◽

Clinical Trials ◽

Extended Release

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L-arginine effect on inflammatory mediators: A systematic review of randomized controlled clinical trials

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000619 ◽

2019 ◽

pp. 1-9 ◽

Cited By ~ 1

Author(s):

Seyed Reza Mirhafez ◽

Mitra Hariri

Keyword(s):

Systematic Review ◽

Clinical Trials ◽

Inflammatory Mediators ◽

Randomized Clinical Trials ◽

Randomized Controlled Clinical Trials ◽

Patients With Cancer ◽

Reactive Protein ◽

Randomized Controlled ◽

Human Adults ◽

Factor Α

Abstract. L-arginine is an important factor in several physiological and biochemical processes. Recently, scientists studied L-arginine effect on inflammatory mediators such as C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6). We conducted a systematic review on randomized controlled trials assessing L-arginine effect on inflammatory mediators. We searched data bases including Google scholar, ISI web of science, SCOPUS, and PubMed/Medline up to April 2019. Randomized clinical trials assessing the effect of L-arginine on inflammatory mediators in human adults were included. Our search retrieved eleven articles with 387 participants. Five articles were on patients with cancer and 6 articles were on adults without cancer. L-arginine was applied in enteral form in 5 articles and in oral form in 6 articles. Eight articles were on both genders, two articles were on women, and one article was on men. L-arginine could not reduce inflammatory mediators among patients with and without cancer except one article which indicated that taking L-arginine for 6 months decreased IL-6 among cardiopathic nondiabetic patients. Our results indicated that L-arginine might not be able to reduce selected inflammatory mediators, but for making a firm decision more studies are needed to be conducted with longer intervention duration, separately on male and female and with different doses of L-arginine.

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