Immunohistochemical Expression of P53 , as a Marker of Apoptosis in Hodgkin's and Non Hodgkin's Lymphoma of the Head and Neck Region

Extra-nodal involvement of non-Hodgkin's lymphoma (NHL) is well described. Skeletal muscle involvement is rare with the muscles of the extremities being most commonly affected. We present a series of six patients that have attended our Joint Head and Neck Ultrasound and Cytopathology clinic. In these cases, skeletal muscle involvement by NHL was demonstrated in the head and neck region. The ultrasound findings in these cases are presented and discussed.

Download Full-text

Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive

The Journal of Laryngology & Otology ◽

10.1017/s0022215120000729 ◽

2020 ◽

Vol 134 (5) ◽

pp. 460-462

Author(s):

L Li ◽

L Hamilton ◽

J Montgomery ◽

M Stewart

Keyword(s):

Squamous Cell Carcinoma ◽

Chronic Lymphocytic Leukaemia ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Hodgkin’S Lymphoma ◽

Lymphocytic Leukaemia ◽

Hodgkin's Lymphoma ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma

AbstractBackgroundPatients with non-Hodgkin's lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with cervical lymph node metastasis, and can pose a diagnostic challenge in patients with non-Hodgkin's lymphoma or chronic lymphocytic leukaemia who may have pre-existing palpable neck nodes.MethodsA retrospective case review of a health board was conducted to identify patients with head and neck squamous cell carcinoma with a previous diagnosis of non-Hodgkin's lymphoma or chronic lymphocytic leukaemia.ResultsFour patients with head and neck squamous cell carcinoma that developed after non-Hodgkin's lymphoma or chronic lymphocytic leukaemia were identified. Two patients had a background of non-Hodgkin's lymphoma treated with chemotherapy. The remaining two patients had a background of chronic lymphocytic leukaemia under active surveillance. Three out of the four patients died within 30 months of diagnosis.ConclusionHead and neck squamous cell carcinoma following non-Hodgkin's lymphoma or chronic lymphocytic leukaemia is aggressive. A heightened clinical suspicion is essential to facilitate early diagnosis and treatment of head and neck squamous cell carcinoma in patients with dual pathology.

Download Full-text

Non-Hodgkin's lymphoma of the head and neck: CT evaluation of nodal and extranodal sites

American Journal of Roentgenology ◽

10.2214/ajr.149.4.785 ◽

1987 ◽

Vol 149 (4) ◽

pp. 785-791 ◽

Cited By ~ 32

Author(s):

HR Harnsberger ◽

DG Bragg ◽

AG Osborn ◽

WR Smoker ◽

WP Dillon ◽

...

Keyword(s):

Head And Neck ◽

Hodgkin’S Lymphoma ◽

Hodgkin's Lymphoma ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma ◽

Ct Evaluation

Download Full-text

Coexistence of laryngeal squamous cell carcinoma and non-Hodgkin's lymphoma with nasopharyngeal involvement

The Journal of Laryngology & Otology ◽

10.1017/s0022215105000782 ◽

2005 ◽

Vol 120 (2) ◽

pp. 1-4 ◽

Cited By ~ 9

Author(s):

Mesut Sabrı Tezer ◽

Ümit Tuncel ◽

Samet Özlügedik ◽

Murat Uzun ◽

Sezer Kulaçoğlu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Hodgkin’S Lymphoma ◽

Laryngeal Squamous Cell Carcinoma ◽

Neck Region ◽

Hodgkin's Lymphoma ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma ◽

Second Primaries

Laryngeal squamous cell carcinoma (SCC) is one of the most frequent malignancies in the head and neck region. The risk of multiple malignancies is reported as 2–11 per cent and most of the second primaries are SCCs. Lymphogenic tumours as second primaries are extremely rare. In this paper, we report a case of laryngeal SCC with synchronous non-Hodgkin's lymphoma and review the literature on the clinical and histopathological aspects of these malignancies.

Download Full-text