Relative cost-effectiveness of a skin protectant in managing venous leg ulcers in the UK

2012 ◽  
Vol 21 (8) ◽  
pp. 389-398 ◽  
Author(s):  
J.F. Guest ◽  
R.R. Taylor ◽  
K. Vowden ◽  
P. Vowden
2009 ◽  
Vol 18 (5) ◽  
pp. 216-224 ◽  
Author(s):  
J.F. Guest ◽  
E. Nagy ◽  
E. Sladkevicius ◽  
P. Vowden ◽  
P. Price

2006 ◽  
Vol 9 (6) ◽  
pp. A225-A226
Author(s):  
P McEwan ◽  
CD Poole ◽  
P Holmes ◽  
AP Tetlow ◽  
CJ Currie

2002 ◽  
Vol 22 (1_suppl) ◽  
pp. 26-37 ◽  
Author(s):  
Fujian Song ◽  
James Raftery ◽  
Paul Aveyard ◽  
Chris Hyde ◽  
Pelham Barton ◽  
...  

To evaluate the relative cost-effectiveness of nicotine replacement therapy (NRT) and bupropion SR for smoking cessation, the authors reviewed published studies and developed a decision analytic model from the UK National Health Services perspective. Irrespective of the methods or assumptions involved, the results of published studies consistently indicated that NRT for smoking cessation is cost-effective. No published studies have evaluated the relative cost-effectiveness of bupropion SR for smoking cessation. The results of the decision analyses indicated that, as compared with advice or counseling alone, the incremental cost per life-years saved is about $1,441~$3,455 for NRT, $920~$2,150 for bupropion SR, and $1,282~$2,836 for NRT plus bupropion SR. The cost-effectiveness of adding NRT and bupropion SR to advice or counseling for smoking cessation is better than many other accepted health care interventions.


2000 ◽  
Vol 15 (1) ◽  
pp. 95-106 ◽  
Author(s):  
Z. Philips ◽  
M. Barraza-Llorens ◽  
J. Posnett

2021 ◽  
Author(s):  
Jing Shen ◽  
Luke Vale ◽  
Beatriz Goulao ◽  
Paul Whybrow ◽  
Stephen Payne ◽  
...  

Abstract Background: Bulbar urethral stricture is a common cause for urinary symptoms in men and its two main treatment options both have drawbacks with little evidence on their relative cost-effectiveness. Current guidelines on the management of recurrent bulbar urethral stricture have been predominantly based on expert opinion and panel consensus.Objective: To assess the relative cost-effectiveness of open urethroplasty and endoscopic urethrotomy as treatment for recurrent urethral stricture in men.Methods: Set in the UK National Health Service with recruitment from 38 hospital sites, a randomised controlled trial of open urethroplasty and endoscopic urethrotomy with 6-monthly follow-up over 24 months was conducted. Two hundred and twenty-two men requiring operative treatment for recurrence of bulbar urethral stricture and having had at least one previous intervention for stricture were recruited. Effectiveness was measured by quality- adjusted life years (QALYs) derived from EQ-5D 5L. Cost-effectiveness was measured by the incremental cost per QALY gained over 24 months using a within trial analysis and a Markov model with a 10-year time horizon. Results: In the within trial, urethroplasty cost on average more than urethrotomy (cost difference: £2148 [95% CI: 689, 3606]) and resulted in a similar number of QALYs on average (QALY difference: -0.01 [95% CI: -0.17, 0.14)] over 24 months. The Markov model produced similar results. Sensitivity analyses using multiple imputation, suggested that the results were robust, despite observed missing data.Conclusions: Based on current practice and evidence, urethrotomy is a cost-effective treatment compared with urethroplasty. Trial registration: ISRCTN: 98009168 (date: 29 November 2012) and it is also in the UK NIHR Portfolio (reference 13507).


2006 ◽  
Vol 9 (6) ◽  
pp. A227-A228
Author(s):  
P McEwan ◽  
AP Tetlow ◽  
P Holmes ◽  
CD Poole ◽  
CJ Currie

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