Bone-anabolic action of low-intensity vibratory stimulation and the involvement of bone microvascularity

2018 ◽  
Vol 2018.30 (0) ◽  
pp. 2C17
Author(s):  
Yuya KAWAHITO ◽  
Takeshi MATSUMOTO
Keyword(s):  
Vibratory Stimulation ◽  
Low Intensity ◽  
Anabolic Action

scholarly journals The second edge of ADHD: an advantage in motor learning and performance with task-irrelevant background vibratory noise

2018 ◽  
Author(s):  
Maria Korman ◽  
Lian Meir-Yalon ◽  
Nebal Egbarieh ◽  
Avi Karni
Keyword(s):  
Motor Learning ◽  
Memory Consolidation ◽  
Vibratory Stimulation ◽  
Learning Deficits ◽  
Low Intensity ◽  
Consolidation Phase ◽  
Noisy Conditions ◽  
And Performance ◽  
Opposition Movements ◽  
Task Irrelevant

AbstractYoung adults with ADHD often gain less than expected from practice sessions well-suited for their peers. Here, we tested whether task-irrelevant, low-intensity vibratory stimulation (VtSt), suggested to modulate motor learning, may compensate for such learning deficits. Participants were given training, either with or without VtSt, on a sequence of finger opposition movements. Under VtSt, typical individuals had reduced overnight, consolidation phase, gains; performance partly recovering one week later. In contrast, participants with ADHD benefitted from VtSt both during the acquisition (online) and the overnight skill consolidation (offline) phases. One week later, both groups showed robust retention of the gains in performance, but when tested with background VtSt, individuals with ADHD outperformed their typical peers. We propose that ADHD can confer advantages in performance, learning and skill memory consolidation in specific ‘noisy’ conditions that adversely affect typical adults; we conjecture that the effects of VtSt are contingent on baseline arousal levels.

Low-Intensity Cognitive Behavioral Therapy

2017 ◽  
Vol 2 (1) ◽  
pp. 31-36
Author(s):  
Pascal Wabnitz ◽  
Michael Schulz ◽  
Michael Löhr ◽  
André Nienaber
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Cognitive Behavioral ◽  
Low Intensity

Maori adaptation of a low intensity mental health intervention in primary care

2012 ◽  
Author(s):  
Fiona Mathieson ◽  
Kara Mihaere ◽  
Sunny Collings ◽  
Anthony Dowell ◽  
James Stanley
Keyword(s):  
Mental Health ◽  
Primary Care ◽  
Health Intervention ◽  
Mental Health Intervention ◽  
Low Intensity

Inhibition rather than Enhancement of Hemostatic System Activation during Initiation of Oral Anticoagulant Treatment

1997 ◽  
Vol 77 (04) ◽  
pp. 685-689 ◽  
Author(s):  
Paul A Kyrle ◽  
Johannes Brockmeier ◽  
Ansgar Weltermann ◽  
Sabine Eichinger ◽  
Wolfgang Speiser ◽  
...  
Keyword(s):  
High Intensity ◽  
Oral Anticoagulant ◽  
Protein C ◽  
Venous Blood ◽  
Rapid Decline ◽  
Oral Anticoagulant Treatment ◽  
Shed Blood ◽  
Low Intensity ◽  
Hemostatic System ◽  
System Activation

SummaryCoumarin-induced skin necrosis is believed to be due to a transient hypercoagulable state resulting from a more rapid decline of the protein C activity relative to that of coagulation factors (F) II, IX and X during initiation of oral anticoagulant therapy. We studied hemostatic system activation during early oral anticoagulant treatment with a technique that investigates coagulation activation in the microcirculation.We determined in 10 healthy volunteers the concentrations of prothrombin fragment F1+2 (f1.2) and thrombin-antithrombin complex (TAT) in blood emerging from an injury of the microvasculature (bleeding time incision) before and after initiation of both high-inten- sity and low-intensity coumarin therapy. In addition, f1.2, TAT, activated F VII (F Vila) and the activities of FII, F VII, F X and protein C were measured in venous blood.A rapid decline of F VII and protein C was observed in venous blood with activities at 24 h of 7 ± 1% and 43 ± 2%, respectively, during the high-intensity regimen. A 20 to 30% reduction of f1.2 and TAT was seen in venous blood at 72 h with no major difference between the high- and the low-intensity regimen. F Vila levels were substantially affected by anticoagulation with a >90% reduction at 48 h during the high-intensity regimen. Following high-intensity coumarin, a >50% decrease in the fl.2 and TAT levels was found in shed blood at 48 h suggesting substantial inhibition of thrombin generation during early oral anticoagulation. An increase in the f1.2 and TAT levels was seen neither in shed blood nor in venous blood.Our data do not support the concept of a transient imbalance between generation and inhibition of thrombin as the underlying pathomechanism of coumarin-induced skin nekrosis.

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