Autobiographical memory in depressed and non-depressed patients with borderline personality disorder

2004 ◽  
Vol 43 (1) ◽  
pp. 17-29 ◽  
Author(s):  
I.P. Kremers ◽  
Ph. Spinhoven ◽  
A.J.W. Does
1999 ◽  
Vol 29 (6) ◽  
pp. 1397-1404 ◽  
Author(s):  
B. JONES ◽  
H. HEARD ◽  
M. STARTUP ◽  
M. SWALES ◽  
J. M. G. WILLIAMS ◽  
...  

Background. This study investigated whether individuals with borderline personality disorder (BPD) tend to be overgeneral in their autobiographical recall and whether the extent of their overgeneral recall covaries with their susceptibilities to dissociative experiences, as expected on theoretical grounds.Methods. Twenty-three patients with BPD and 23 matched controls completed the Autobiographical Memory Test (AMT) and self-report measures of depression, anxiety, trait anger and dissociative experiences.Results. Participants with BPD scored significantly higher than the control group on the measures of depression, anxiety, trait anger, and dissociative experiences and also retrieved significantly more general memories on the AMT. The number of general memories retrieved by the BPD group correlated significantly with their dissociation scores but not with their scores on mood measures.Conclusions. Patients with BPD have difficulties in recalling specific autobiographical memories. These difficulties are related to their tendency to dissociate and may help them to avoid episodic information that would evoke acutely negative affect.


2006 ◽  
Vol 40 (3) ◽  
pp. 225-229 ◽  
Author(s):  
Peter R. Joyce ◽  
Janice M. McKenzie ◽  
Roger T. Mulder ◽  
Suzanne E. Luty ◽  
Patrick F. Sullivan ◽  
...  

Objective: To examine whether the T allele of G protein β3 (GNβ3) is associated with self-mutilation in depressed patients. Method: A history of self-mutilation was systematically inquired about when recruiting depressed patients for a long-term treatment trial. Risk factors such as borderline personality disorder and childhood abuse experiences were systematically assessed, and patients were genotyped for polymorphisms of GNβ 3. Results: The T allele of GNβ 3, borderline personality disorder and childhood sexual abuse were all significantly associated with self-mutilation in depressed patients. These associations were significant in both univariate andmultivariate analyses, and as predicted were stronger in young depressed patients than in depressed patients of all ages. Conclusions: If the association between the T allele of GNβ 3and self-mutilation can be replicated, this may provide clues to understanding the neurobiology of self-mutilation.


1986 ◽  
Vol 15 (3) ◽  
pp. 201-211 ◽  
Author(s):  
Rex W. Cowdry ◽  
David Pickar ◽  
Robert Davies

Symptomatology and electroencephalographic abnormalities were examined in thirty-nine individuals with borderline personality disorder, compared with twenty unipolar depressed patients. Borderline individuals showed a much higher incidence of symptoms commonly seen in complex partial seizures or episodic dyscontrol, and in addition had a much higher incidence of EEG abnormalities, particularly posterior sharp activity. These findings suggest that neurophysiological dysfunction may contribute to the borderline syndrome.


2005 ◽  
Vol 29 (3) ◽  
pp. 343-358 ◽  
Author(s):  
Babette Renneberg ◽  
Erika Theobald ◽  
Monika Nobs ◽  
Matthias Weisbrod

2019 ◽  
Vol 33 (6) ◽  
pp. 818-831 ◽  
Author(s):  
Eszter Beran ◽  
Mara J. Richman ◽  
Zsolt Unoka

Borderline personality disorder (BPD) is characterized by impaired functioning of autobiographical memory (AM). We use a quantitative meta-analysis to assess AM performance in adults diagnosed with BPD as compared to healthy controls (HC). Moderator variables included type of autobiographical memory as well as clinical and demographic variables. Large significant deficits were seen in the BPD group in comparison to the HC group. In the BPD group, effect sizes were large for overgenerality, omission, and specific memories, while not significant for recall. Age influenced the performance of the BPD group; in addition, there was a significant interaction between age and specificity of memory. Gender and IQ did not influence memory performance. Our results confirm that BPD patients show impairment in AM. We explain these impairments in terms of the CaR-FA-X model, based on mechanisms of capture and rumination, functional avoidance, and impaired executive control.


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