scholarly journals Cell-derived biomimetic drug delivery systems for cancer therapy

2019 ◽  
Vol 49 (9) ◽  
pp. 1203-1212
Author(s):  
Yan Zou ◽  
Wenya He ◽  
Bingyang Shi ◽  
Meng Zheng
2020 ◽  
Vol 21 (11) ◽  
pp. 1084-1098
Author(s):  
Fengqian Chen ◽  
Yunzhen Shi ◽  
Jinming Zhang ◽  
Qi Liu

This review summarizes the epigenetic mechanisms of deoxyribonucleic acid (DNA) methylation, histone modifications in cancer and the epigenetic modifications in cancer therapy. Due to their undesired side effects, the use of epigenetic drugs as chemo-drugs in cancer therapies is limited. The drug delivery system opens a door for minimizing these side effects and achieving greater therapeutic benefits. The limitations of current epigenetic therapies in clinical cancer treatment and the advantages of using drug delivery systems for epigenetic agents are also discussed. Combining drug delivery systems with epigenetic therapy is a promising approach to reaching a high therapeutic index and minimizing the side effects.


Author(s):  
Sauraj ◽  
Anuj Kumar ◽  
Bijender Kumar ◽  
Ruchir Priyadarshi ◽  
Chhavi Sharma ◽  
...  

Author(s):  
Daryl C. Drummond ◽  
Dmitri Kirpotin ◽  
Christopher C. Benz ◽  
John W. Park ◽  
Keelung Hong

Author(s):  
Bessi Qorri ◽  
Alexandria DeCarlo ◽  
Matthew Mellon ◽  
Myron R. Szewczuk

Nanoscale ◽  
2019 ◽  
Vol 11 (14) ◽  
pp. 6519-6532 ◽  
Author(s):  
Lucie Reinišová ◽  
Soňa Hermanová ◽  
Martin Pumera

A biomedical perspective is used to assess micro/nanomotor-based anticancer drug delivery systems with recommendations for their effective future development.


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