A Novel Monte Carlo Simulation of Light Transport in the Human Finger towards Non-Invasive Measurement of Blood Hemoglobin Concentration

2005 ◽  
Author(s):  
Gideon Barnea ◽  
Harel Primack
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Hemoglobin Concentration ◽  
Light Transport ◽  
Non Invasive ◽  
Blood Hemoglobin ◽  
Human Finger ◽  
Blood Hemoglobin Concentration ◽  
Invasive Measurement

scholarly journals Simulation of Photon Propagation in Tissue Using Matlab

2013 ◽  
Vol 21 (Special-Issue) ◽  
pp. 31-36b ◽  
Author(s):  
Dominika Jurovata ◽  
Julia Kurnatova ◽  
Sebastian Ley ◽  
Daniel Laqua ◽  
Pavel Vazan ◽  
...  
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Oxygen Saturation ◽  
Pulse Oximetry ◽  
Fetal Tissue ◽  
Light Transport ◽  
Photon Propagation ◽  
Non Invasive ◽  
Radiation Distribution ◽  
Propagation Rules

Abstract This paper deals with the light transport, photon trajectory and its radiation in tissue. A model based on Monte Carlo simulation has been implemented in Matlab to get inside into photon interaction with tissue. The project is aimed to non-invasive pulse oximetry measurement of fetal oxygen saturation in the maternal abdomen. One of the fundamental challenges is to ensure a sufficient penetration depth which covers maternal and fetal tissue. This contribution investigates the photon trajectories and analyse the number of photons which stayed in tissue and their radiation distribution. The principle and photon propagation rules, needed for simulation, are presented in this article. Finally the results are compared with literature.

scholarly journals The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?

Blood ◽  
2006 ◽  
Vol 107 (5) ◽  
pp. 1747-1750 ◽  
Author(s):  
Ernest Beutler ◽  
Jill Waalen
Keyword(s):  
Normal Distribution ◽  
Lower Limit ◽  
Population Distribution ◽  
Hemoglobin Concentration ◽  
Blood Hemoglobin ◽  
Definition Of ◽  
Lower Limit Of Normal ◽  
Blood Hemoglobin Concentration

The diagnosis of anemia is an important aspect of the practice of hematology. The first step is to decide whether the patient is, in fact, anemic. Unless earlier blood counts are available, and they often are not, the physician must make his or her decision on the basis of the population distribution of hemoglobin values. How likely is it that the patient's hemoglobin value lies below the normal distribution; that is, “the lower limit”?

scholarly journals Curvilinear VO2:Power Output Relationship in a Ramp Test in Professional Cyclists: Possible Association with Blood Hemoglobin Concentration.

2002 ◽  
Vol 52 (1) ◽  
pp. 95-103 ◽  
Author(s):  
Alejandro Lucía ◽  
Jesús Hoyos ◽  
Alfredo Santalla ◽  
Margarita Pérez ◽  
José L. Chicharro
Keyword(s):  
Power Output ◽  
Hemoglobin Concentration ◽  
Ramp Test ◽  
Blood Hemoglobin ◽  
Blood Hemoglobin Concentration

scholarly journals Splenic contraction-induced reversible increase in hemoglobin concentration in intermittent hypoxia

1999 ◽  
Vol 86 (1) ◽  
pp. 181-187 ◽  
Author(s):  
Ichiro Kuwahira ◽  
Uguri Kamiya ◽  
Tokuzen Iwamoto ◽  
Yoshihiro Moue ◽  
Tetsuya Urano ◽  
...  
Keyword(s):  
Intermittent Hypoxia ◽  
Hemoglobin Concentration ◽  
Hypoxic Exposure ◽  
Plasma Epinephrine ◽  
Receptor Stimulation ◽  
Blood Hemoglobin ◽  
Underlying Mechanisms ◽  
Blood Hemoglobin Concentration

The effect of intermittent hypoxia (IHx) on blood hemoglobin concentration ([Hb]) and the underlying mechanisms were studied in rats exposed to 10% O2, 1 h/day, for up to 5 wk. IHx protocols with longer daily hypoxic exposure show persistent polycythemia; however, it is unknown whether [Hb] increases transiently during hypoxia in protocols without polycythemia. Hypoxia produced a reversible [Hb] increase after 4 days of IHx but not in normoxic controls (NxC) or after shorter period of IHx. Splenectomy abolished the phenomenon. Plasma epinephrine and norepinephrine levels during hypoxia were comparable in IHx and NxC groups, but the epinephrine-induced [Hb] increase was larger in IHx. The α1- and α2-adrenoreceptor blockade (phentolamine) and α2-blockade (yohimbine) abolished the [Hb] increase of IHx rats. Conversely, α2-receptor stimulation (oxymetazoline) increased [Hb] during normoxia in IHx but not in NxC. In conclusion, this IHx protocol results in reversible [Hb] increases during hypoxia via splenic contraction mediated by increased α2-adrenoreceptor response. This may protect O2supply during hypoxia without the cardiovascular burden of polycythemia during normoxia.

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