Real-Time Dynamics of Single Protein-Small Molecule Interactions with Label-Free, Free-Solution Double-Nanohole Optical Trapping

2014 ◽  
Author(s):  
Ahmed A. Al Balushi ◽  
Reuven Gordon
Keyword(s):  
Real Time ◽  
Small Molecule ◽  
Optical Trapping ◽  
Free Solution ◽  
Label Free ◽  
Time Dynamics ◽  
Single Protein ◽  
Molecule Interactions

Pre-equilibration kinetic size-exclusion chromatography with mass spectrometry detection (peKSEC-MS) for label-free solution-based kinetic analysis of protein–small molecule interactions

The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 990-994 ◽  
Author(s):  
Jiayin Bao ◽  
Svetlana M. Krylova ◽  
Leonid T. Cherney ◽  
J. C. Yves Le Blanc ◽  
Patrick Pribil ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Kinetic Analysis ◽  
Small Molecule ◽  
Size Exclusion ◽  
Free Solution ◽  
Label Free ◽  
Mass Spectrometry Detection ◽  
Reversible Binding ◽  
Exclusion Chromatography ◽  
Molecule Interactions

Label-free solution-based kinetic analysis of reversible binding between protein and small molecule.

Real-time small molecule binding detection using a label-free photonic crystal biosensor

2010 ◽  
Author(s):  
Yunbo Guo ◽  
Jing Yong Ye ◽  
Baohua Huang ◽  
Daniel McNerny ◽  
Thommey P. Thomas ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Real Time ◽  
Small Molecule ◽  
Label Free

A label-free optical technique for detecting small molecule interactions

2002 ◽  
Vol 17 (9) ◽  
pp. 827-834 ◽  
Author(s):  
Bo Lin ◽  
Jean Qiu ◽  
John Gerstenmeier ◽  
Peter Li ◽  
Homer Pien ◽  
...  
Keyword(s):  
Small Molecule ◽  
Optical Technique ◽  
Label Free ◽  
Molecule Interactions

Kinetic Capillary Electrophoresis with Mass-Spectrometry Detection (KCE-MS) Facilitates Label-Free Solution-Based Kinetic Analysis of Protein-Small Molecule Binding

ChemBioChem ◽  
2011 ◽  
Vol 12 (17) ◽  
pp. 2551-2554 ◽  
Author(s):  
Jiayin Bao ◽  
Svetlana M. Krylova ◽  
Derek J. Wilson ◽  
Oren Reinstein ◽  
Philip E. Johnson ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Capillary Electrophoresis ◽  
Kinetic Analysis ◽  
Small Molecule ◽  
Free Solution ◽  
Label Free ◽  
Mass Spectrometry Detection ◽  
Kinetic Capillary Electrophoresis

Acoustic coupling of transverse waves as a mechanism for the label-free detection of protein–small molecule interactions

The Analyst ◽  
2002 ◽  
Vol 127 (12) ◽  
pp. 1596-1600 ◽  
Author(s):  
Emma-Louise Lyle ◽  
Gordon L. Hayward ◽  
Michael Thompson
Keyword(s):  
Small Molecule ◽  
Label Free ◽  
Transverse Waves ◽  
Acoustic Coupling ◽  
Label Free Detection ◽  
Molecule Interactions
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