scholarly journals Application of RNAi to Genomic Drug Target Validation in Schistosomes

2015 ◽  
Vol 9 (5) ◽  
pp. e0003801 ◽  
Author(s):  
Alessandra Guidi ◽  
Nuha R. Mansour ◽  
Ross A. Paveley ◽  
Ian M. Carruthers ◽  
Jérémy Besnard ◽  
...  
Keyword(s):  
Drug Target ◽  
Target Validation ◽  
Drug Target Validation

Case study: use of a library of antisense inhibitors for gene functionalization and drug target validation

2004 ◽  
Vol 3 (3) ◽  
pp. 117-122 ◽  
Author(s):  
Eric G Marcusson ◽  
Thomas M Vincent ◽  
Kumar L Hari ◽  
MingYi Chiang ◽  
Nicholas M Dean
Keyword(s):  
Drug Target ◽  
Target Validation ◽  
Drug Target Validation

scholarly journals Drug Target Validation Methods in Malaria - Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation

2017 ◽  
Vol 18 (9) ◽  
Author(s):  
Kamila A. Meissner ◽  
Sergey Lunev ◽  
Yuan-Ze Wang ◽  
Marleen Linzke ◽  
Fernando de Assis Batista ◽  
...  
Keyword(s):  
Drug Target ◽  
Specific Drug ◽  
Target Validation ◽  
Validation Methods ◽  
Drug Target Validation

scholarly journals Phenome-wide association studies across large population cohorts support drug target validation

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Dorothée Diogo ◽  
Chao Tian ◽  
Christopher S. Franklin ◽  
Mervi Alanne-Kinnunen ◽  
Michael March ◽  
...  
Keyword(s):  
Drug Target ◽  
Association Studies ◽  
Large Population ◽  
Target Validation ◽  
Drug Target Validation

scholarly journals Drug target validation of the trypanothione pathway enzymes through metabolic modelling

FEBS Journal ◽  
2012 ◽  
Vol 279 (10) ◽  
pp. 1811-1833 ◽  
Author(s):  
Viridiana Olin-Sandoval ◽  
Zabdi González-Chávez ◽  
Miriam Berzunza-Cruz ◽  
Ignacio Martínez ◽  
Ricardo Jasso-Chávez ◽  
...  
Keyword(s):  
Drug Target ◽  
Target Validation ◽  
Metabolic Modelling ◽  
Drug Target Validation

scholarly journals Genetic drug target validation using Mendelian randomisation

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Amand F. Schmidt ◽  
Chris Finan ◽  
Maria Gordillo-Marañón ◽  
Folkert W. Asselbergs ◽  
Daniel F. Freitag ◽  
...  
Keyword(s):  
Drug Target ◽  
Mendelian Randomisation ◽  
Target Validation ◽  
Drug Target Validation
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