Target Identification and Validation in Drug Discovery - Methods in Molecular Biology
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Published By Humana Press

9781627033107, 9781627033114

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The Path to Oncology Drug Target Validation: An Industry Perspective

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_1 ◽

2013 ◽

pp. 3-13 ◽

Cited By ~ 3

Author(s):

Marta Cortés-Cros ◽

Tobias Schmelzle ◽

Volker M. Stucke ◽

Francesco Hofmann

Keyword(s):

Drug Target ◽

Target Validation ◽

Oncology Drug ◽

Drug Target Validation

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A Cell Culture System That Mimics Chronic Lymphocytic Leukemia Cells Microenvironment for Drug Screening and Characterization

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_14 ◽

2013 ◽

pp. 217-226 ◽

Cited By ~ 4

Author(s):

Alessandro Natoni ◽

Michael O’Dwyer ◽

Corrado Santocanale

Keyword(s):

Cell Culture ◽

Chronic Lymphocytic Leukemia ◽

Drug Screening ◽

Culture System ◽

Lymphocytic Leukemia ◽

Leukemia Cells ◽

Cell Culture System ◽

A Cell

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Structure-Based Target Druggability Assessment

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_10 ◽

2013 ◽

pp. 141-164 ◽

Cited By ~ 13

Author(s):

Jean-Yves Trosset ◽

Nicolas Vodovar

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Genetically Engineered Animal Models for In Vivo Target Identification and Validation in Oncology

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_18 ◽

2013 ◽

pp. 281-305 ◽

Cited By ~ 4

Author(s):

Gemma Texidó

Keyword(s):

Animal Models ◽

Target Identification ◽

Genetically Engineered

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Validating Pharmacological Disruption of Protein–Protein Interactions by Acceptor Photobleaching FRET Imaging

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_11 ◽

2013 ◽

pp. 165-178 ◽

Cited By ~ 7

Author(s):

Janos Roszik ◽

Gábor Tóth ◽

János Szöllősi ◽

György Vereb

Keyword(s):

Protein Interactions ◽

Protein Protein Interactions ◽

Acceptor Photobleaching

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Two-Dimensional vs. Three-Dimensional In Vitro Tumor Migration and Invasion Assays

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_15 ◽

2013 ◽

pp. 227-252 ◽

Cited By ~ 20

Author(s):

Miriam Zimmermann ◽

Carol Box ◽

Suzanne A. Eccles

Keyword(s):

Three Dimensional ◽

Migration And Invasion ◽

Two Dimensional ◽

Invasion Assays

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Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_7 ◽

2013 ◽

pp. 97-104 ◽

Cited By ~ 2

Author(s):

Konstantinos Drosopoulos ◽

Spiros Linardopoulos

Keyword(s):

Drug Development ◽

Small Molecule

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The Neurosphere Assay Applied to Neural Stem Cells and Cancer Stem Cells

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_17 ◽

2013 ◽

pp. 267-277 ◽

Cited By ~ 13

Author(s):

Rossella Galli

Keyword(s):

Stem Cells ◽

Cancer Stem Cells ◽

Neural Stem Cells ◽

Neurosphere Assay

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High-Throughput RNAi Screening for the Identification of Novel Targets

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_6 ◽

2013 ◽

pp. 89-95 ◽

Cited By ~ 4

Author(s):

Meredith C. Henderson ◽

David O. Azorsa

Keyword(s):

High Throughput ◽

Rnai Screening ◽

Novel Targets

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PARP Inhibition as a Prototype for Synthetic Lethal Screens

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-62703-311-4_9 ◽

2013 ◽

pp. 123-137 ◽

Cited By ~ 2

Author(s):

Xuesong Liu

Keyword(s):

Parp Inhibition ◽

Synthetic Lethal

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Target Identification and Validation in Drug Discovery - Methods in Molecular BiologyLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Humana Press

The Path to Oncology Drug Target Validation: An Industry Perspective

A Cell Culture System That Mimics Chronic Lymphocytic Leukemia Cells Microenvironment for Drug Screening and Characterization

Structure-Based Target Druggability Assessment

Genetically Engineered Animal Models for In Vivo Target Identification and Validation in Oncology

Validating Pharmacological Disruption of Protein–Protein Interactions by Acceptor Photobleaching FRET Imaging

Two-Dimensional vs. Three-Dimensional In Vitro Tumor Migration and Invasion Assays

Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development

The Neurosphere Assay Applied to Neural Stem Cells and Cancer Stem Cells

High-Throughput RNAi Screening for the Identification of Novel Targets

PARP Inhibition as a Prototype for Synthetic Lethal Screens

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology
Latest Publications