scholarly journals Comparison of diagnostic accuracy of magnetic resonance elastography and Fibroscan for detecting liver fibrosis in chronic hepatitis B patients: A systematic review and meta-analysis

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0186660 ◽  
Author(s):  
Huanming Xiao ◽  
Meijie Shi ◽  
Yubao Xie ◽  
Xiaoling Chi
Keyword(s):  
Systematic Review ◽  
Chronic Hepatitis ◽  
Magnetic Resonance ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Diagnostic Accuracy ◽  
Chronic Hepatitis B ◽  
Meta Analysis ◽  
Magnetic Resonance Elastography

scholarly journals Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Xiaolong Qi ◽  
Min An ◽  
Tongwei Wu ◽  
Deke Jiang ◽  
Mengyun Peng ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Diagnostic Accuracy ◽  
Chronic Hepatitis B ◽  
Transient Elastography ◽  
Meta Analysis ◽  
Receiver Operating Curve ◽  
Significant Fibrosis ◽  
Receiver Operating

Background. The hepatitis B virus infection is a global health issue and the stage of liver fibrosis affects the prognosis in patients with chronic hepatitis B (CHB). We performed the meta-analysis describing diagnostic accuracy of transient elastography (TE) for predicting CHB-related fibrosis. Methods. We performed an adequate literature search to identify studies that assessed the diagnostic accuracy of TE in CHB patients using biopsy as reference standard. Hierarchical summary receiver-operating curves model and the bivariate mixed-effects binary regression model were applied to generate summary receiver-operating characteristic curves and pooled estimates of sensitivity and specificity. Results. The area under the summary receiver-operating curve for significant fibrosis and cirrhosis was 0.86 (95% confidence interval (CI): 0.83–0.89) and 0.92 (95% CI: 0.90–0.94), respectively. The sensitivity, specificity, and diagnostic odds ratio of TE for significant fibrosis were 0.78 (95% CI: 0.73–0.81, p<0.01; I2=85.59%), 0.81 (95% CI: 0.77–0.84, p<0.01; I2=88.20%), and 14.44 (95% CI: 10.80–19.31, p<0.01; I2=100%) and for cirrhosis were 0.84 (95% CI: 0.80–0.88, p<0.01; I2=76.67%), 0.87 (95% CI: 0.84–0.90, p<0.01; I2=90.89%), and 36.63 (95% CI: 25.38–52.87, p<0.01; I2=100%), respectively. The optimal cut-off values of TE were 7.25 kPa for diagnosing significant fibrosis and 12.4 kPa for diagnosing cirrhosis, respectively. Conclusion. TE is of great value in the detection of patients with CHB-related cirrhosis but has a suboptimal accuracy in the detection of significant fibrosis.

Liver Fibrosis in the Natural Course of Chronic Hepatitis B Viral Infection: A Systematic Review with Meta-Analysis

2021 ◽  
Author(s):  
Mei-Hong Lin ◽  
Hai-Qiong Li ◽  
Lin Zhu ◽  
Hai-Ying Su ◽  
Li-Shan Peng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Viral Infection ◽  
Chronic Hepatitis B ◽  
Meta Analysis ◽  
Natural Course ◽  
Hepatitis B Viral Infection

Magnetic resonance elastography for the detection and staging of liver fibrosis in chronic hepatitis B

2013 ◽  
Vol 24 (1) ◽  
pp. 70-78 ◽  
Author(s):  
Sudhakar Kundapur Venkatesh ◽  
Gang Wang ◽  
Seng Gee Lim ◽  
Aileen Wee
Keyword(s):  
Chronic Hepatitis ◽  
Magnetic Resonance ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Magnetic Resonance Elastography

scholarly journals Therapeutic vaccination for chronic hepatitis B: A systematic review and meta‐analysis

2019 ◽  
Vol 26 (7) ◽  
pp. 803-817 ◽  
Author(s):  
Seng Gee Lim ◽  
Jennielyn Agcaoili ◽  
Nurun Nisa Amatullah De Souza ◽  
Edwin Chan
Keyword(s):  
Systematic Review ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Meta Analysis ◽  
Therapeutic Vaccination

Systematic review with meta‐analysis: the impact of functional cure on clinical outcomes in patients with chronic hepatitis B

2021 ◽  
Author(s):  
Anusha Vittal ◽  
Disha Sharma ◽  
Alvin Hu ◽  
Nehna A. Majeed ◽  
Nancy Terry ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Clinical Outcomes ◽  
Chronic Hepatitis B ◽  
Meta Analysis ◽  
Functional Cure ◽  
The Impact
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