Illict drug use and academia in North Kosovo: Prevalence, patterns, predictors and health-related quality of life

Abstract Background This study was aimed to evaluate the health-related quality of life (HRQoL) and its drivers among recreational drug users, compared to non-users using WHOQOL-BREF. Methods A total of 246 recreational drug users and 141 non-recreational drug users were recruited using consecutive sampling of adults in the community. Socio-demographic data, data related to recreational drug use and HRQoL were collected. Data were compared using t-test, analysis of variance and chi-square test. Determinants of HRQoL were obtained using multivariate regression models. Results The mean overall quality of life (OQOL) score was significantly higher for non-recreational drug users compared to users (75.89 ± 22.64 vs 61.08 ± 23.94, respectively, p < 0.001), non-users as well had significantly higher mean scores across all four domains of WHOQOL-BREF. After multivariable adjustment, use of recreational drugs negatively affected the psychological domain (β=-4.17, 95% CI -8.22 to -0,13) and the environmental domain (β=-4.47, 95% CI -8.48 to -0.45). Years of recreational drug use affected the social relationship domain (β=-0.55, 95% CI -0.88 to -0.22), OQOL (β=-0.57, 95% CI -0.94 to -0.19), and general health satisfaction (β=-0.71, 95% CI -1.08 to -0.35). Number of recreational drugs used contributed to poorer physical health (β=-1.45, 95% CI -2.57 to -0.33), psychological domain (β=-2.04, 95% CI -3.18 to -0.91), social relationship domain (β=-1.87, 95% CI -3.39 to -0.35) as well as overall quality of life (β=-2.13, 95% CI -3.89 to -0.37). Besides recreational drugs, monthly income also affected physical health (β = 5.17, 95% CI 2.96 to 7.38), psychological domain (β = 3.34, 95% CI 1.10 to 5.58), environmental domain (β = 2.64, 95% CI 0.42 to 4.85) and also the OQOL (β = 4.16, 95% CI 0.70 to 7.62). Conclusions Our findings suggest that, recreational drugs significantly negatively affect the health-related quality of life of its users. People who use multiple recreational drugs and longer years of recreational drug use had a more widespread effect across the health domains. Higher monthly income could improve the HRQoL of recreational drug users.

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Potentially Inappropriate Drug Use and Health-Related Quality of Life in the Elderly

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy ◽

10.1592/phco.26.6.768 ◽

2006 ◽

Vol 26 (6) ◽

pp. 768-778 ◽

Cited By ~ 33

Author(s):

Duska M Franic ◽

Jenny Z Jiang

Keyword(s):

Quality Of Life ◽

Drug Use ◽

The Elderly ◽

Inappropriate Drug ◽

Health Related Quality ◽

Inappropriate Drug Use ◽

Related Quality ◽

Health Related

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Health-related Quality of Life Among People Who Inject Drugs on Methadone Assisted Treatment in Zanzibar, Tanzania

10.21203/rs.3.rs-584571/v1 ◽

2021 ◽

Author(s):

Shaaban Hassan Haji ◽

Damian Jeremia Damian ◽

Nahir Ali Rajab ◽

Othman Mkubwa Ali ◽

Asha Ussi Khamis ◽

...

Keyword(s):

Quality Of Life ◽

Drug Use ◽

People Who Inject Drugs ◽

Life Questionnaire ◽

Health Related Quality ◽

Cross Sectional ◽

Related Quality ◽

Health Related ◽

Improve Health

Abstract Background: The burden of drug use is growing rapidly in Low- and Middle-Income countries (LMICs) with access to coastlines and most major cities;Tanzania is not exception. Methadone Assisted Treatment (MAT) has a potential to reduce addiction and therefore health and quality of lives. MAT is known to improve health related quality of life and it is essential in addressing a number of drug use related challenges among People Who Inject Drugs (PWIDS). Evidence on the profiles of Health Related Quality of Life (HRQOL) among PWIDS who are in treatment programmes particualry MAT services, is scanty in Zanzibar, Tanzania, Objectives: To determine HRQOL and associated factors among PWIDS receiving MAT Services in Zanzibar, Tanzania. Methods: This was a cross-sectional study conducted in Unguja, Zanzibar from July to August 2019. A total of 376 PWIDS attending Kidongo Chekundu MAT clinic were randomly selected and enrolled in the study. Data were electronically collected using Open Data Kit (ODK) programme during face-to-face interviews with PWIDS HRQOL was measured using the WHO's Quality of Life questionnaire Descriptive and binary logistic regression analyses were used to describe and determine factors independently associated with HRQOL. Results: Of the 376 PWIDS enrolled in this study, Vast majority (92.6%) were male. The mean age of participants at enrollment was 39 (± standard deviation (SD) 8.9). Slightly more than one third (45.5%) were single, 56.4% have a secondary school education level. Slightly more than two third (82.7%) were employed, 42% reported living at Magharibi B districts. High proportion were on MAT services for more than one year (70.2%); had good adherence to MAT services (79%), and were receving 50 – 99 mg of methadodone dose per day (51.1%).The majority of PWIDS (82%) had of high HRQOL. Employed PWIDS [AOR=5.36; 95%CI (1.51, 19.04); p=0.009], and PWIDS who were in the middle wealth quintile [OR=24.15; 95%CI (2.01, 290.30); p=0.012] were more likely to have better HRQOL. Conclusion: In general, PWIDS on MAT services have good HRQOL in Zanzibar. Being employed or having better economic status among were associated with better HRQOL. To effect this there is a need to strengthen multisectoral collaborations, integrated and comprehensive MAT services within the clinic and other related areas with all relevant stakeholders so as to improve health related quality of life among PWIDS.

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