Gang Talk and Strategic Moralisations in Danish Drug Policy Discourses on Young and Recreational Drug Users

In Denmark, a moralization of recreational use of drugs has lately occurred. The use is interpreted in a neo-liberal framing seeing the user who can chose as selfish, not regarding the negative consequences of drug use in a wider sense, and the legislation has been sharpened.

Recreational Drug Using Behaviour and Legal Benzylpiperazine Party Pills

<p>Benzylpiperazine (BZP) is a stimulant drug that produces effects similar to amphetamines (Campbell, Cline, Evans, Lloyd, & Peck, 1973). It has been sold legally in New Zealand in the form of 'party pills' since 2000. The legal status of BZP party pills has been debated in New Zealand as the media reported cases of apparent overdoses and adverse reactions leading to hospitalization (Brogden, 2005; Crewdson, 2007; Reiber, 2005; Rankin, 2006). Representatives of the BZP party pill industry publicly defended their product claiming that BZP party pills were reducing substance related harm by reducing illicit substance use (Bowden, 2007b, p.1). They also claimed that banning BZP would result in an increase in use of illicit substances, especially methamphetamine or 'P' (Barnett, 2007). The overall aim of this thesis is to test the claims that BZP party pills reduce substance related harm by reducing illicit substance use, and to identify potential outcomes of a BZP party pill ban. In addition, the perceived risks of party pill and other drug use will be examined. In chapter one I review key concepts relating to BZP party pill use: recreational drug use, harm reduction, and risk perception. In chapter two the history and New Zealand context of BZP party pills are reviewed. In chapter three, study one qualitatively analyzes BZP party pill marketing material in an attempt to describe the culture and discourse promoted by the BZP party pill industry. This analysis demonstrated that BZP party pills were primarily marketed as part of a recreational drug using culture. In chapter four, study two quantitatively investigated whether BZP party pill use was associated with reduced levels of illicit substance use in a sample (N=796) of first year university students. This study also examined the relationship between risk perception and frequency of substance use. Study two demonstrated that BZP party pill users are generally recreational poly-drug users who used illicit substances equally as often as illicit users who did not use BZP party pills. BZP party pills did not appear to reduce illicit substance use, and therefore harm. For the majority of substances there was no significant relationship between risk and use behaviour. The legal status of substances appeared to be important when participants rated the risks of use. Legal substances (including BZP) tended to be rated as safer than illegal substances. In chapter five, study three qualitatively analyzed 60 interviews with regular BZP party pill users to identify potential outcomes of a BZP party pill ban. A combination of alternatives were likely to be used by BZP party pill users, primarily illicit substances, especially ecstasy, as well as alcohol, and black market BZP. However methamphetamine (P) was an unpopular alternative. Study three also analyzed how BZP party pill users assess the costs and benefits of BZP party pill use. Decisions to use BZP party pills relied heavily on the benefits of use, rather than the costs. In chapter six, the general discussion describes the implications, ethical considerations, limitations, and outcomes of the research.</p>

Recreational Drug Using Behaviour and Legal Benzylpiperazine Party Pills

<p>Benzylpiperazine (BZP) is a stimulant drug that produces effects similar to amphetamines (Campbell, Cline, Evans, Lloyd, & Peck, 1973). It has been sold legally in New Zealand in the form of 'party pills' since 2000. The legal status of BZP party pills has been debated in New Zealand as the media reported cases of apparent overdoses and adverse reactions leading to hospitalization (Brogden, 2005; Crewdson, 2007; Reiber, 2005; Rankin, 2006). Representatives of the BZP party pill industry publicly defended their product claiming that BZP party pills were reducing substance related harm by reducing illicit substance use (Bowden, 2007b, p.1). They also claimed that banning BZP would result in an increase in use of illicit substances, especially methamphetamine or 'P' (Barnett, 2007). The overall aim of this thesis is to test the claims that BZP party pills reduce substance related harm by reducing illicit substance use, and to identify potential outcomes of a BZP party pill ban. In addition, the perceived risks of party pill and other drug use will be examined. In chapter one I review key concepts relating to BZP party pill use: recreational drug use, harm reduction, and risk perception. In chapter two the history and New Zealand context of BZP party pills are reviewed. In chapter three, study one qualitatively analyzes BZP party pill marketing material in an attempt to describe the culture and discourse promoted by the BZP party pill industry. This analysis demonstrated that BZP party pills were primarily marketed as part of a recreational drug using culture. In chapter four, study two quantitatively investigated whether BZP party pill use was associated with reduced levels of illicit substance use in a sample (N=796) of first year university students. This study also examined the relationship between risk perception and frequency of substance use. Study two demonstrated that BZP party pill users are generally recreational poly-drug users who used illicit substances equally as often as illicit users who did not use BZP party pills. BZP party pills did not appear to reduce illicit substance use, and therefore harm. For the majority of substances there was no significant relationship between risk and use behaviour. The legal status of substances appeared to be important when participants rated the risks of use. Legal substances (including BZP) tended to be rated as safer than illegal substances. In chapter five, study three qualitatively analyzed 60 interviews with regular BZP party pill users to identify potential outcomes of a BZP party pill ban. A combination of alternatives were likely to be used by BZP party pill users, primarily illicit substances, especially ecstasy, as well as alcohol, and black market BZP. However methamphetamine (P) was an unpopular alternative. Study three also analyzed how BZP party pill users assess the costs and benefits of BZP party pill use. Decisions to use BZP party pills relied heavily on the benefits of use, rather than the costs. In chapter six, the general discussion describes the implications, ethical considerations, limitations, and outcomes of the research.</p>

Invasive Fungal Sinusitis: Clinical Pathologic Characteristics of Acute vs. Chronic Infections

Introduction/Objective Invasive fungal sinusitis is a serious condition requiring early diagnosis and treatment. It has been classified into acute, chronic and granulomatous forms. This study aims to investigate clinical pathologic aspects such as a) Frequency of mass forming lesions, b) Frequency of granulomatous reaction, c) Frequency of acute inflammatory reaction and d) Frequency of angioinvasion, perineural invasion and necrosis, to determine if these factors allow a more meaningful clinical-pathologic classification. Methods/Case Report Cases of invasive fungal sinusitis with surgical pathology specimens available in our laboratory since January 1, 2006 to date were gathered. Electronic medical records, histopathologic diagnostic material and laboratory fungal identification results were reviewed. Results (if a Case Study enter NA) Thirty-one cases of invasive fungal sinusitis were found: Twenty-two were acute (&lt; 4wk duration) and 9 chronic. Patient comorbidities in acute cases were malignancies: 45%, diabetes mellitus: 26% and solid organ transplant: 10%. Among patients with malignancies, 5 cases had relapsed/refractory acute myeloid leukemia with neutropenia &lt; 1000/uL. Patients with diabetes mellitus exhibited an average HbA1c of 10.0%. Two out of 3 transplant patients had graft versus host disease. The most common causative fungi were species of Aspergillus, Candida and mucormycetes. By contrast, a third of the chronic cases had a history of recreational drug use and six presented with space occupying lesions seen on imaging studies. Upon histologic review, four of these showed granulomas and the majority of cases exhibited extensive necrosis. Among necrotic cases, perineural and vascular invasion by fungal organisms was identified. Conclusion We report the contrasting clinical pathologic characteristics of acute and chronic invasive fungal sinusitis in a series of cases treated at University affiliated tertiary/quaternary-care Hospitals. Acute invasive sinusitis is usually a complication of severe systemic diseases. Chronic cases are caused by various medical conditions including the use of recreational drug and may mimic neoplasms on imaging.

Sex, Drugs, and Genes: Illuminating the Moral Condemnation of Recreational Drugs

Over the past decade, evolutionary psychologists have proposed that many moral stances function to promote self-interests. At the same time, behavioral geneticists have demonstrated that many moral stances have genetic bases. We integrated these perspectives by examining how moral condemnation of recreational drug use relates to sexual strategy (i.e., being more vs. less open to sex outside of a committed relationship) in a sample of Finnish twins and siblings ( N = 8,118). Twin modeling suggested that genetic factors accounted for 53%, 46%, and 41% of the variance in drug condemnation, sociosexuality, and sexual-disgust sensitivity, respectively. Further, approximately 75% of the phenotypic covariance between drug condemnation and sexual strategy was accounted for by genes, and there was substantial overlap in the genetic effects underlying both drug condemnation and sexual strategy ( rg = .41). Results are consistent with the proposal that some moral sentiments are calibrated to promote strategic sexual interests, which arise partially via genetic factors.

Health-Related Quality Of Life And Its Determinants Among Recreational Drug Users In A Rural Area In Cameroon: A Cross-Sectional Study

Background This study was aimed to evaluate the health-related quality of life (HRQoL) and its drivers among recreational drug users, compared to non-users using WHOQOL-BREF. Methods A total of 246 recreational drug users and 141 non-recreational drug users were recruited using consecutive sampling of adults in the community. Socio-demographic data, data related to recreational drug use and HRQoL were collected. Data were compared using t-test, analysis of variance and chi-square test. Determinants of HRQoL were obtained using multivariate regression models. Results The mean overall quality of life (OQOL) score was significantly higher for non-recreational drug users compared to users (75.89 ± 22.64 vs 61.08 ± 23.94, respectively, p < 0.001), non-users as well had significantly higher mean scores across all four domains of WHOQOL-BREF. After multivariable adjustment, use of recreational drugs negatively affected the psychological domain (β=-4.17, 95% CI -8.22 to -0,13) and the environmental domain (β=-4.47, 95% CI -8.48 to -0.45). Years of recreational drug use affected the social relationship domain (β=-0.55, 95% CI -0.88 to -0.22), OQOL (β=-0.57, 95% CI -0.94 to -0.19), and general health satisfaction (β=-0.71, 95% CI -1.08 to -0.35). Number of recreational drugs used contributed to poorer physical health (β=-1.45, 95% CI -2.57 to -0.33), psychological domain (β=-2.04, 95% CI -3.18 to -0.91), social relationship domain (β=-1.87, 95% CI -3.39 to -0.35) as well as overall quality of life (β=-2.13, 95% CI -3.89 to -0.37). Besides recreational drugs, monthly income also affected physical health (β = 5.17, 95% CI 2.96 to 7.38), psychological domain (β = 3.34, 95% CI 1.10 to 5.58), environmental domain (β = 2.64, 95% CI 0.42 to 4.85) and also the OQOL (β = 4.16, 95% CI 0.70 to 7.62). Conclusions Our findings suggest that, recreational drugs significantly negatively affect the health-related quality of life of its users. People who use multiple recreational drugs and longer years of recreational drug use had a more widespread effect across the health domains. Higher monthly income could improve the HRQoL of recreational drug users.