scholarly journals Changes in central venous-to-arterial carbon dioxide tension induced by fluid bolus in critically ill patients

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257314
Author(s):  
Charalampos Pierrakos ◽  
David De Bels ◽  
Thomas Nguyen ◽  
Dimitrios Velissaris ◽  
Rachid Attou ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Central Venous Oxygen Saturation ◽  
Carbon Dioxide Tension ◽  
Arterial Carbon Dioxide Tension ◽  
Central Venous ◽  
Fluid Bolus ◽  
Arterial Carbon Dioxide ◽  
Venous Oxygen Saturation

Background In this prospective observational study, we evaluated the effects of fluid bolus (FB) on venous-to-arterial carbon dioxide tension (PvaCO2) in 42 adult critically ill patients with pre-infusion PvaCO2 > 6 mmHg. Results FB caused a decrease in PvaCO2, from 8.7 [7.6−10.9] mmHg to 6.9 [5.8−8.6] mmHg (p < 0.01). PvaCO2 decreased independently of pre-infusion cardiac index and PvaCO2 changes during FB were not correlated with changes in central venous oxygen saturation (ScvO2) whatever pre-infusion CI. Pre-infusion levels of PvaCO2 were inversely correlated with decreases in PvaCO2 during FB and a pre-infusion PvaCO2 value < 7.7 mmHg could exclude a decrease in PvaCO2 during FB (AUC: 0.79, 95%CI 0.64–0.93; Sensitivity, 91%; Specificity, 55%; p < 0.01). Conclusions Fluid bolus decreased abnormal PvaCO2 levels independently of pre-infusion CI. Low baseline PvaCO2 values suggest that a positive response to FB is unlikely.

scholarly journals Correlation between central venous-arterial carbon dioxide tension gradient and cardiac index changes following fluid therapy

2010 ◽  
Vol 13 (3) ◽  
pp. 269 ◽  
Author(s):  
Alexandre Yazigi ◽  
Hicham Abou-Zeid ◽  
Fadia Haddad ◽  
Samia Madi-Jebara ◽  
Gemma Hayeck ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Cardiac Index ◽  
Fluid Therapy ◽  
Carbon Dioxide Tension ◽  
Arterial Carbon Dioxide Tension ◽  
Central Venous ◽  
Arterial Carbon Dioxide ◽  
Index Changes

Central Venous-Arterial Carbon Dioxide Tension Gradient: Another Marker to Define Fluid Responsiveness

2011 ◽  
Vol 70 (4) ◽  
pp. 1014-1015
Author(s):  
Alexandre Yazigi ◽  
Hicham Abou-Zeid ◽  
Fadia Haddad ◽  
Samia Madi-Jebara ◽  
Khalil Jabbour
Keyword(s):  
Carbon Dioxide ◽  
Fluid Responsiveness ◽  
Carbon Dioxide Tension ◽  
Arterial Carbon Dioxide Tension ◽  
Central Venous ◽  
Arterial Carbon Dioxide

Investigating spectroscopic measurement of sublingual veins and tissue to estimate central venous oxygen saturation

2021 ◽  
pp. 1-9
Author(s):  
Aslinur Sircan-Kucuksayan ◽  
Oktay Eray ◽  
Murat Buyukaksu ◽  
Birce Gumus ◽  
Oguz Dursun ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Near Infrared ◽  
Arterial Oxygen Saturation ◽  
Central Venous Oxygen Saturation ◽  
Arterial Oxygen ◽  
Central Venous ◽  
Venous Oxygen Saturation ◽  
Oxygenation Status

BACKGROUND: Venous oxygen saturation reflects venous oxygenation status and can be used to assess treatment and prognosis in critically ill patients. A novel method that can measure central venous oxygen saturation (ScvO2) non-invasively may be beneficial and has the potential to change the management routine of critically ill patients. OBJECTIVE: The study aims to evaluate the potential of sublingual venous oxygen saturation (SsvO2) to be used in the estimation of ScvO2. METHODS: We have developed two different approaches to calculate SsvO2. In the first one, near-infrared spectroscopy (NIRS) measurements were performed directly on the sublingual veins. In the second approach, NIRS spectra were acquired from the sublingual tissue apart from the sublingual veins, and arterial oxygen saturation was measured using a pulse oximeter on the fingertip. RESULTS: Twenty-six healthy subjects were included in the study. In the first and second approaches, average SsvO2 values were 75.0% ± 1.8 and 75.8% ± 2.1, respectively. The results of the two different approaches were close to each other and similar to ScvO2 of healthy persons (> 70%). CONCLUSION: Oxygen saturation of sublingual veins has the potential to be used in intensive care units, non-invasively and in real-time, to estimate ScvO2.

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