scholarly journals Effects of crystalloids and colloids on microcirculation, central venous oxygen saturation, and central venous-to-arterial carbon dioxide gap in a rabbit model of hemorrhagic shock

2018 ◽  
Vol 33 (1) ◽  
pp. 108-117 ◽  
Author(s):  
Makiko Komori ◽  
Yuriko Samejima ◽  
Keiko Okamura ◽  
Junko Ichikawa ◽  
Mitsuharu Kodaka ◽  
...  
2014 ◽  
Vol 58 (5) ◽  
pp. 611-619 ◽  
Author(s):  
M. NÉMETH ◽  
K. TÁNCZOS ◽  
G. DEMETER ◽  
D. ÉRCES ◽  
J. KASZAKI ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257314
Author(s):  
Charalampos Pierrakos ◽  
David De Bels ◽  
Thomas Nguyen ◽  
Dimitrios Velissaris ◽  
Rachid Attou ◽  
...  

Background In this prospective observational study, we evaluated the effects of fluid bolus (FB) on venous-to-arterial carbon dioxide tension (PvaCO2) in 42 adult critically ill patients with pre-infusion PvaCO2 > 6 mmHg. Results FB caused a decrease in PvaCO2, from 8.7 [7.6−10.9] mmHg to 6.9 [5.8−8.6] mmHg (p < 0.01). PvaCO2 decreased independently of pre-infusion cardiac index and PvaCO2 changes during FB were not correlated with changes in central venous oxygen saturation (ScvO2) whatever pre-infusion CI. Pre-infusion levels of PvaCO2 were inversely correlated with decreases in PvaCO2 during FB and a pre-infusion PvaCO2 value < 7.7 mmHg could exclude a decrease in PvaCO2 during FB (AUC: 0.79, 95%CI 0.64–0.93; Sensitivity, 91%; Specificity, 55%; p < 0.01). Conclusions Fluid bolus decreased abnormal PvaCO2 levels independently of pre-infusion CI. Low baseline PvaCO2 values suggest that a positive response to FB is unlikely.


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