scholarly journals Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells

2017 ◽  
Vol 13 (2) ◽  
pp. e1006164 ◽  
Author(s):  
James R. Bowen ◽  
Kendra M. Quicke ◽  
Mohan S. Maddur ◽  
Justin T. O’Neal ◽  
Circe E. McDonald ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Zika Virus ◽  
Type I Interferon ◽  
Type I ◽  
Human Dendritic Cells ◽  
Interferon Responses

scholarly journals Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells

2018 ◽  
Vol 9 ◽  
Author(s):  
Tünde Fekete ◽  
Dora Bencze ◽  
Attila Szabo ◽  
Eszter Csoma ◽  
Tamas Biro ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Inflammatory Responses ◽  
Type I Interferon ◽  
Type I ◽  
Human Dendritic Cells

scholarly journals Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

2011 ◽  
Vol 85 (6) ◽  
pp. 3042-3042
Author(s):  
J. R. Rodriguez-Madoz ◽  
D. Bernal-Rubio ◽  
D. Kaminski ◽  
K. Boyd ◽  
A. Fernandez-Sesma
Keyword(s):  
Dendritic Cells ◽  
Dengue Virus ◽  
Type I Interferon ◽  
Type I ◽  
Human Dendritic Cells

scholarly journals Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

2007 ◽  
Vol 204 (10) ◽  
pp. 2489-2489 ◽  
Author(s):  
Kavita M. Dhodapkar ◽  
Devi Banerjee ◽  
John Connolly ◽  
Anjli Kukreja ◽  
Elyana Matayeva ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Type I Interferon ◽  
Interferon Response ◽  
Type I ◽  
Fcγ Receptor ◽  
Selective Blockade ◽  
Human Dendritic Cells

scholarly journals Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection

2011 ◽  
Vol 7 (11) ◽  
pp. e1002345 ◽  
Author(s):  
Bruno Moltedo ◽  
Wenjing Li ◽  
Jacob S. Yount ◽  
Thomas M. Moran
Keyword(s):  
Dendritic Cells ◽  
Influenza Virus ◽  
Virus Infection ◽  
Type I Interferon ◽  
Influenza Virus Infection ◽  
Type I ◽  
Unique Type ◽  
Interferon Responses

scholarly journals Contribution of Double-Stranded RNA and CPSF30 Binding Domains of Influenza Virus NS1 to the Inhibition of Type I Interferon Production and Activation of Human Dendritic Cells

2012 ◽  
Vol 87 (5) ◽  
pp. 2430-2440 ◽  
Author(s):  
I. Ramos ◽  
E. Carnero ◽  
D. Bernal-Rubio ◽  
C. W. Seibert ◽  
L. Westera ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Influenza Virus ◽  
Type I Interferon ◽  
Type I ◽  
Interferon Production ◽  
Double Stranded Rna ◽  
Binding Domains ◽  
Human Dendritic Cells

scholarly journals Lassa Virus Nucleoprotein Mutants Generated by Reverse Genetics Induce a Robust Type I Interferon Response in Human Dendritic Cells and Macrophages

2011 ◽  
Vol 85 (22) ◽  
pp. 12093-12097 ◽  
Author(s):  
X. Carnec ◽  
S. Baize ◽  
S. Reynard ◽  
L. Diancourt ◽  
V. Caro ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Reverse Genetics ◽  
Type I Interferon ◽  
Interferon Response ◽  
Lassa Virus ◽  
Type I ◽  
Human Dendritic Cells

scholarly journals Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

2007 ◽  
Vol 204 (10) ◽  
pp. 2494-2494
Author(s):  
Kavita M. Dhodapkar ◽  
Devi Banerjee ◽  
John Connolly ◽  
Anjli Kukreja ◽  
Elyana Matayeva ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Type I Interferon ◽  
Interferon Response ◽  
Type I ◽  
Fcγ Receptor ◽  
Selective Blockade ◽  
Human Dendritic Cells

scholarly journals Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

2010 ◽  
Vol 84 (9) ◽  
pp. 4845-4850 ◽  
Author(s):  
Juan R. Rodriguez-Madoz ◽  
Dabeiba Bernal-Rubio ◽  
Dorota Kaminski ◽  
Kelley Boyd ◽  
Ana Fernandez-Sesma
Keyword(s):  
Dendritic Cells ◽  
Dengue Virus ◽  
Type I Interferon ◽  
Productive Infection ◽  
Type I ◽  
Human Immune ◽  
Alpha Beta ◽  
Human Dendritic Cells

ABSTRACT Dengue virus (DENV) infects human immune cells in vitro and likely infects dendritic cells (DCs) in vivo. DENV-2 productive infection induces activation and release of high levels of chemokines and proinflammatory cytokines in monocyte-derived DCs (moDCs), with the notable exception of alpha/beta interferon (IFN-α/β). Interestingly, DENV-2-infected moDCs fail to prime T cells, most likely due to the lack of IFN-α/β released by moDCs, since this effect was reversed by addition of exogenous IFN-β. Together, our data show that inhibition of IFN-α/β production by DENV in primary human moDCs is a novel mechanism of immune evasion.

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