Effect of Inhaled Heparin on Methacholine-Induced Bronchial Hyperreactivity

CHEST Journal ◽  
1995 ◽  
Vol 107 (4) ◽  
pp. 1009-1012 ◽  
Author(s):  
Berrin Ceyhan ◽  
Turgay Celikel
Keyword(s):  
Bronchial Hyperreactivity

Inhibition of airways inflammation by dexamethasone is followed by reduced bronchial hyperreactivity in BP2 mice

1996 ◽  
Vol 26 (8) ◽  
pp. 971-979
Author(s):  
S.-Y. EUM ◽  
C. CREMINON ◽  
S. HAILE ◽  
J. LEFORT ◽  
B. B. VARGAFTIG
Keyword(s):  
Bronchial Hyperreactivity ◽  
Airways Inflammation

scholarly journals Effect of the S -nitrosoglutathione reductase inhibitor N6022 on bronchial hyperreactivity in asthma

2018 ◽  
Vol 6 (2) ◽  
pp. 322-331 ◽  
Author(s):  
Loretta G. Que ◽  
Zhonghui Yang ◽  
Njira L. Lugogo ◽  
Rohit K. Katial ◽  
Steven A. Shoemaker ◽  
...  
Keyword(s):  
Reductase Inhibitor ◽  
Bronchial Hyperreactivity

Eosinophils and Mast Cells in Bronchoalveolar Lavage in Subjects with Mild Asthma: Relationship to Bronchial Hyperreactivity

1988 ◽  
Vol 137 (1) ◽  
pp. 62-69 ◽  
Author(s):  
A. J. Wardlaw ◽  
Sandra Dunnette ◽  
G. J. Gleich ◽  
J. V. Collins ◽  
A. B. Kay
Keyword(s):  
Mast Cells ◽  
Bronchoalveolar Lavage ◽  
Bronchial Hyperreactivity ◽  
Mild Asthma

Bronchial hyperreactivity in patients with atopic dermatitis

1998 ◽  
Vol 16 ◽  
pp. S192
Author(s):  
Elwira Paluchowska ◽  
Karina Jahnz-Różyk ◽  
Sławomir Majewski ◽  
Zbigniew Samochocki ◽  
Małgorzata Faber
Keyword(s):  
Atopic Dermatitis ◽  
Bronchial Hyperreactivity

Analysis of factors associated with bronchial hyperreactivity to methacholine in bronchiectasis

Lung ◽  
1991 ◽  
Vol 169 (1) ◽  
pp. 43-51 ◽  
Author(s):  
M. Ip ◽  
W. K. Lam ◽  
S. Y. So ◽  
E. Liong ◽  
C. Y. Chan ◽  
...  
Keyword(s):  
Bronchial Hyperreactivity ◽  
Factors Associated

Effect of obesity on bronchial hyperreactivity among Latino children

2013 ◽  
Vol 48 (12) ◽  
pp. 1201-1205 ◽  
Author(s):  
Blanca E. Del Rio-Navarro ◽  
Virginia Blandon-Vijil ◽  
Alberto J. Escalante-Domínguez ◽  
Arturo Berber ◽  
Jose A. Castro-Rodriguez
Keyword(s):  
Bronchial Hyperreactivity ◽  
Latino Children

SLOWING THE DETERIORATION OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE OBSERVED DURING BRONCHODILATOR THERAPY BY ADDING INHALED CORTICOSTEROIDS: A 4-YEAR PROSPECTIVE STUDY

PEDIATRICS ◽  
1994 ◽  
Vol 94 (2) ◽  
pp. 269-270
Author(s):  
Peter Cvietusa ◽  
Joseph Spahn ◽  
William R. Otto
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Function ◽  
Pulmonary Disease ◽  
Bronchial Hyperreactivity ◽  
Rapid Decline ◽  
Chronic Obstructive ◽  
Exacerbation Rate ◽  
Obstructive Pulmonary Disease ◽  
Bronchodilator Therapy ◽  
Inhaled Steroids

Purpose of the Study. To determine if the deterioration in lung function, seen in adults with asthma or chronic obstructive pulmonary disease (COPD), could be reversed or slowed by the addition of inhaled beclomethasone. Many short-term studies have shown the benefits of inhaled steroids in asthma; in particular, their ability to improve pulmonary function, decrease bronchial hyperreactivity, and reduce symptoms. Few studies have evaluated the long-term effects of inhaled steroids on the clinical course of either asthma or COPD. Methods. This report is an extension of a 2-year study that followed 160 patients with asthma or COPD on bronchodilator therapy alone. From this group, 56 patients who displayed a rapid decline in pulmonary function (FEV1 ≥ 80 ml/year) and a high exacerbation rate (≥1/year) were selected to receive additional treatment with beclomethasone dipropionate 400 µg two times daily over 4 years. FEV1 and airways responsiveness to histamine were measured every 6 months and at 1 and 13 months upon completion of the study. Peak flows and symptom scores were recorded weekly, and compliance, inhaler technique, and adverse affects were monitored every 3 months. Findings. During the first 6 months of beclomethasone treatment, both groups showed a significant improvement in pre- and postbronchodilator FEV1 with the most significant change noted in the asthma group. Thereafter, the FEV1 began to decline again, as it had in the first 2 years of the study, but at a rate that was 33% slower. In addition to slowing the decline in FEV1, inhaled beclomethasone resulted in a substantial decrease in the degree of bronchial hyperreactivity, and peak flow rates improved.

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