THE OXYGEN DESATURATION INDEX: A VALUABLE PARAMETER FROM NOCTURNAL PULSE OXIMETRY MONITORING

CHEST Journal ◽  
2007 ◽  
Vol 132 (4) ◽  
pp. 647B ◽  
Author(s):  
Fidaa Shaib ◽  
Jinesh Mehta ◽  
Yasmeen Shaw ◽  
Maria Cirino-Marcano ◽  
Ihab Hamzeh
Keyword(s):  
Pulse Oximetry ◽  
Oxygen Desaturation ◽  
Desaturation Index ◽  
Oxygen Desaturation Index

Observational study to define reference ranges for the 3% oxygen desaturation index during sleep in healthy children under 12 years using oximetry motion-resistant technology

2020 ◽  
pp. archdischild-2020-320066 ◽  
Author(s):  
Jonathan Wen Yi Ong ◽  
Daniel Williams ◽  
Johanna C Gavlak ◽  
Natasha Liddle ◽  
Paula Lowe ◽  
...  
Keyword(s):  
Pulse Oximetry ◽  
Sleep Disordered Breathing ◽  
Oxygen Desaturation ◽  
Reference Ranges ◽  
Healthy Children ◽  
Mean Values ◽  
Desaturation Index ◽  
Oxygen Desaturation Index ◽  
The Mean ◽  
Pulse Oximeters

ObjectiveTo define reference ranges for the 3% oxygen desaturation index (DI3) in healthy children under 12 years old during sleep.DesignObservational.SettingHome.SubjectsHealthy children aged 6 months to 12 years of age.InterventionNocturnal pulse oximetry at home. Parents documented sleep times. Visi-Download software (Stowood Scientific) analysed data with artefact and wake periods removed.Main outcome measuresThe following oximetry parameters used in the assessment of sleep-disordered breathing conditions were measured: 3% (DI3) and 4% (DI4) oxygen desaturation indices—the number of times per hour where the oxygen saturation falls by at least 3% or 4% from baseline, mean saturations (SAT50), minimum saturations (SATmin), delta index 12 s (DI12s), and percentage time with saturations below 92% and 90%.ResultsSeventy-nine children underwent nocturnal home pulse oximetry, from which there were 66 studies suitable for analysis. The median values for DI3 and DI4 were 2.58 (95% CI 1.96 to 3.10) and 0.92 (95% CI 0.73 to 1.15), respectively. The 95th and 97.5th centiles for DI3 were 6.43 and 7.06, respectively, which inform our cut-off value for normality. The mean values for SAT50 and SATmin were 97.57% (95% CI 97.38% to 97.76%) and 91.09% (95% CI 90.32% to 91.86%), respectively.ConclusionIn children aged 6 months to 12 years, we define normality of the 3% oxygen desaturation index as <7 using standalone, motion-resistant pulse oximeters with short averaging times.

Oxygen Desaturation Index from Nocturnal Oximetry

2012 ◽  
Vol 114 (5) ◽  
pp. 993-1000 ◽  
Author(s):  
Frances Chung ◽  
Pu Liao ◽  
Hisham Elsaid ◽  
Sazzadul Islam ◽  
Colin M Shapiro ◽  
...  
Keyword(s):  
Oxygen Desaturation ◽  
Desaturation Index ◽  
Oxygen Desaturation Index ◽  
Nocturnal Oximetry

Simple screening model for identifying the risk of sleep apnea in patients on opioids for chronic pain

2021 ◽  
pp. rapm-2020-102388
Author(s):  
Janannii Selvanathan ◽  
Rida Waseem ◽  
Philip Peng ◽  
Jean Wong ◽  
Clodagh M Ryan ◽  
...  
Keyword(s):  
At Risk ◽  
Chronic Pain ◽  
Sleep Apnea ◽  
Simple Model ◽  
Oxygen Desaturation ◽  
Desaturation Index ◽  
Oxygen Desaturation Index ◽  
Pain Clinics ◽  
Overnight Oximetry ◽  
Severe Sleep Apnea

BackgroundThere is an increased risk of sleep apnea in patients using opioids for chronic pain. We hypothesized that a simple model comprizing of: (1) STOP-Bang questionnaire and resting daytime oxyhemoglobin saturation (SpO2); and (2) overnight oximetry will identify those at risk of moderate-to-severe sleep apnea in patients with chronic pain.MethodAdults on opioids for chronic pain were recruited from pain clinics. Participants completed the STOP-Bang questionnaire, resting daytime SpO2, and in-laboratory polysomnography. Overnight oximetry was performed at home to derive the Oxygen Desaturation Index. A STOP-Bang score ≥3 or resting daytime SpO2 ≤95% were used as thresholds for the first step, and for those identified at risk, overnight oximetry was used for further screening. The Oxygen Desaturation Index from overnight oximetry was validated against the Apnea-Hypopnea Index (≥15 events/hour) from polysomnography.ResultsOf 199 participants (52.5±12.8 years, 58% women), 159 (79.9%) had a STOP-Bang score ≥3 or resting SpO2 ≤95% and entered the second step (overnight oximetry). Using an Oxygen Desaturation Index ≥5 events/hour, the model had a sensitivity of 86.4% and specificity of 52% for identifying moderate-to-severe sleep apnea. The number of participants who would require diagnostic sleep studies was decreased by 38% from Step 1 to Step 2 of the model.ConclusionA simple model using STOP-Bang questionnaire and resting daytime SpO2, followed by overnight oximetry, can identify those at high risk of moderate-to-severe sleep apnea in patients using opioids for chronic pain.Trial registration numberNCT02513836.

scholarly journals Impact of Sleep Apnea on Cardioembolic Risk in Patients With Atrial Fibrillation

Stroke ◽  
2020 ◽  
Author(s):  
Martino F. Pengo ◽  
Andrea Faini ◽  
Ludger Grote ◽  
Ondrej Ludka ◽  
Pavol Joppa ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sleep Apnea ◽  
Accurate Determination ◽  
Oxygen Desaturation ◽  
Desaturation Index ◽  
Oxygen Desaturation Index ◽  
Obstructive Sleep ◽  
Initial Cohort

Background and Purpose: An accurate determination of the cardioembolic risk in patients with atrial fibrillation (AF) is crucial to prevent consequences like stroke. Obstructive sleep apnea (OSA) is a known risk factor for both AF and stroke. We aim to explore a possible association between OSA and an increased cardioembolic risk in patients with AF. Methods: We assessed data from the ESADA (European Sleep Apnea Database) cohort where patients with known AF and OSA were included. Parameters of OSA severity and related hypoxia like lowest Sp o 2 and 4% oxygen desaturation index were analyzed. Patients were stratified according to their cardioembolic risk estimated with the CHA 2 DS 2 -VASc score. Results: From the initial cohort of 14 646 patients, a final set of 363 patients were included in the analysis. Indices of hypoxia during sleep were associated with increased CHA 2 DS 2 -VASc score (4% oxygen desaturation index 17.9 versus 29.6 versus 30.5 events/hour and the lowest Sp o 2 81.2 versus 77.8 versus 77.5% for low, moderate, and high cardioembolic risk, respectively, P <0.05). Conclusions: These results support the potential role of OSA-related hypoxia in the risk for cardioembolic complications such as stroke in patients with AF.

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