Thrombocytopenia and Sideroblastic Anemia with Pyrazinoic Acid Amide (Pyrazinamide) Therapy

CHEST Journal ◽

10.1378/chest.57.4.378 ◽

1970 ◽

Vol 57 (4) ◽

pp. 378-381 ◽

Author(s):

R.K. MacCurdy ◽

E.R. Simon

Keyword(s):

Sideroblastic Anemia ◽

Pyrazinoic Acid

Download Full-text

Pyrazinoic Acid Amide-An Agent Active Against Experimental Murine Tuberculosis

Experimental Biology and Medicine ◽

10.3181/00379727-79-19447 ◽

1952 ◽

Vol 79 (4) ◽

pp. 563-565 ◽

Author(s):

M. Solotorovsky ◽

F. J. Gregory ◽

E. J. Ironson ◽

E. J. Bugie ◽

R. C. O'Neill ◽

...

Keyword(s):

Pyrazinoic Acid

Download Full-text

Reversible Sideroblastic Anemia Caused by Pyrazinoic Acid (Pyrazinamide®)

Annals of Internal Medicine ◽

10.7326/0003-4819-64-6-1280 ◽

1966 ◽

Vol 64 (6) ◽

pp. 1280 ◽

Keyword(s):

Sideroblastic Anemia ◽

Pyrazinoic Acid

Download Full-text

Lipophilic pyrazinoic acid amide and ester prodrugs

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2009.02.012 ◽

2009 ◽

Vol 37 (3-4) ◽

pp. 257-263 ◽

Author(s):

Marta Filipa Simões ◽

Emília Valente ◽

M. José Rodríguez Gómez ◽

Elsa Anes ◽

Luís Constantino

Keyword(s):

Ester Prodrugs ◽

Pyrazinoic Acid

Download Full-text

Faculty Opinions recommendation of Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717956659.793461149 ◽

2012 ◽

Author(s):

Jaap van Laar ◽

Steven O'Reilly

Keyword(s):

Fatty Acid Amide Hydrolase ◽

Amide Hydrolase ◽

Fatty Acid Amide

Download Full-text

Faculty of 1000 evaluation for An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.717965600.793466602 ◽

2012 ◽

Author(s):

Arun Bhaskar

Keyword(s):

Clinical Trial ◽

Fatty Acid Amide Hydrolase ◽

Controlled Clinical Trial ◽

Osteoarthritis Of The Knee ◽

Amide Hydrolase ◽

Effective Analgesia ◽

Fatty Acid Amide

Download Full-text

Faculty Opinions recommendation of Elevated anandamide, enhanced recall of fear extinction, and attenuated stress responses following inhibition of fatty acid amide hydrolase: A randomized, controlled experimental medicine trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736464037.793566019 ◽

2019 ◽

Author(s):

Yavin Shaham

Keyword(s):

Stress Responses ◽

Fatty Acid Amide Hydrolase ◽

Fear Extinction ◽

Experimental Medicine ◽

Randomized Controlled ◽

Amide Hydrolase ◽

Fatty Acid Amide

Download Full-text

Design, Synthesis and Evaluation of Novel Derivatives of Orotic Acid Amide as Potent Glucokinase Activators

Letters in Drug Design & Discovery ◽

10.2174/1570180813666161013150056 ◽

2017 ◽

Vol 14 (3) ◽

pp. 252-261 ◽

Author(s):

Leilei Zhang ◽

Shengquan Hu ◽

Lei Lei ◽

Yuliang Zhang ◽

Lijing Zhang ◽

...

Keyword(s):

Orotic Acid ◽

Design Synthesis ◽

Glucokinase Activators ◽

Download Full-text

QSAR Study on a Series of Aryl Carboxylic Acid Amide Derivatives as Potential Inhibitors of Dihydroorotate Dehydrogenase (DHODH)

Medicinal Chemistry ◽

10.2174/1573406411309020007 ◽

2013 ◽

Vol 9 (2) ◽

pp. 222-239 ◽

Author(s):

Vivek K. Vyas ◽

Manjunath Ghate

Keyword(s):

Carboxylic Acid ◽

Dihydroorotate Dehydrogenase ◽

Carboxylic Acid Amide ◽

Amide Derivatives ◽

Potential Inhibitors

Download Full-text

1H, 15N, 13C resonance assignments for pyrazinoic acid binding domain of ribosomal protein S1 from Mycobacterium tuberculosis

Biomolecular NMR Assignments ◽

10.1007/s12104-016-9692-9 ◽

2016 ◽

Vol 10 (2) ◽

pp. 321-324 ◽

Author(s):

Biling Huang ◽

Jinglin Fu ◽

Chenyun Guo ◽

Xueji Wu ◽

Donghai Lin ◽

...

Keyword(s):

Mycobacterium Tuberculosis ◽

Ribosomal Protein ◽

Resonance Assignments ◽

Binding Domain ◽

Ribosomal Protein S1 ◽

Pyrazinoic Acid

Download Full-text

4-[(2,4-Dichlorophenyl)carbamoyl]butanoic Acid

Molbank ◽

10.3390/m1227 ◽

2021 ◽

Vol 2021 (2) ◽

pp. M1227

Author(s):

Bibi Hanifa ◽

Muhammad Sirajuddin ◽

Zafran Ullah ◽

Sumera Mahboob ◽

See Mun Lee ◽

...

Keyword(s):

Torsion Angle ◽

Spectroscopic Characterization ◽

Amide Hydrogen ◽

Butanoic Acid ◽

X Ray ◽

Amide Derivative

The synthesis and spectroscopic characterization of the glutaric acid-amide derivative, 2,4-Cl2C6H3N(H)C(=O)(CH2)3C(=O)OH (1), are described. The X-ray crystal structure determination of (1) shows the backbone of the molecule to be kinked about the methylene-C–N(amide) bond as seen in the C(p)–N–C(m)–C(m) torsion angle of −157.0(2)°; m = methylene and p = phenyl. An additional twist in the molecule is noted between the amide and phenyl groups as reflected in the C(m)–N–C(p)–C(p) torsion angle of 138.2(2)°. The most prominent feature of the molecular packing is the formation of supramolecular tapes assembled through carboxylic acid-O–H…O(carbonyl) and amide-N–H…O(amide) hydrogen bonding.

Download Full-text