Characterization, Molecular Docking, Antimicrobial and Anticancer Studies on 5-Bromo
salicylaldehyde-furan-2-yl-methanamine Condensed Schiff Base Rare Earth Metal Complexes
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This work described the synthesis and characterization of 1-(furan-2-yl) methanamine condensed with 5-bromo-2-hydroxybenzaldehyde Schiff base rare earth metal (Ln3+, Pr3+, Nd3+, Sm3+ and Eu3+) complexes.. They were characterized using relevant spectral techniques and docked against microbial target proteins (1H9Z, 3ZBO) theoretically. The experimental antibacterial and anticancer activities (HeLa, MCF7) of these metal complexes were investigated for biological efficacy. Out of five metal complexes, Pr3+ complex exposed good biological efficacy result in both assays.
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