ROLE OF ULTRASOUND AND CT SCAN IN EVALUATING FOCAL LIVER LESIONS

SummaryIntroduction. The liver is a parenchimal abdominal organ with wide variety of primary benign or malignant tumors as well as metastatic tumors.Aim of the study. Was to evaluate the informativity and usefulness of abdominal ultrasound (US) and computer tomography (CT) imaging results in diagnostics of focal liver lesions.Material and methods. The study was conducted in Pauls Stradins Clinical University Hospital. Retrospective analysis of 126 patients with focal liver lesions was performed in the time period of 5 years (2009 till 2014). The medical records of patients with focal liver lesions were analyzed. Primary diagnosis detected by US or CT was evaluated and compared with final morphology after surgical operation or liver biopsy. The obtained results were expressed in percent and analyzed. Sensitivity and specificity of CT scan to detect malignant hepatic lesions was estimated and expressed as percentage with 95% confidence interval.Results. A total of 126 patients with diagnosed liver lesions were included in the study. 96 patients were in the group with performed liver CT scans, with median age of 58.9 years. 30 patients were included in the group with liver US, with median age of 60.1 years. Liver biopsy under US control was performed for 95 patients, but surgical operations with liver resections for 31 patients. 86 patients had malignant liver lesions, but 40 had benign liver lesions. In the US group primary and final diagnosis agreement was in 26 (87%) cases, but diagnosis disagreement in 4 (13%) cases. Diagnosis disagreement was found in 26 (27.1%) cases in the CT group, but agreement was in 70 (72.9%) cases. Overall sensitivity of CT to detect malignant hepatic lesions was 95.2% (95%CI 86.7-98.3%) and specificity was 64.7% (95%CI 47.9-78.5%).Conclusions. CT is a good imaging method for detection of focal liver lesions. In case of unclear diagnosis, percutaneous liver puncture biopsy is recommended. It is mandatory to develop a unified CT scan and US investigation protocol to improve the quality of investigation as well as further treatment tactics.

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The role of Doppler Perfusion Index as screening test in the characterization of focal liver lesions

Digestive and Liver Disease ◽

10.1016/j.dld.2007.12.020 ◽

2008 ◽

Vol 40 (9) ◽

pp. 755-760 ◽

Cited By ~ 1

Author(s):

K. Kyriakopoulou ◽

A. Antoniou ◽

I.V. Fezoulidis ◽

N.L. Kelekis ◽

G.N. Dalekos ◽

...

Keyword(s):

Screening Test ◽

Perfusion Index ◽

Focal Liver Lesions ◽

Liver Lesions

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Effects of Gray-Scale Ultrasonography Immediate Post-Contrast on Characterization of Focal Liver Lesions

BioMed Research International ◽

10.1155/2015/193178 ◽

2015 ◽

Vol 2015 ◽

pp. 1-11

Author(s):

Wei Yang ◽

Min-Hua Chen ◽

Wei Wu ◽

Ying Dai ◽

Zhi-Hui Fan

Keyword(s):

Interventional Procedure ◽

Hepatic Metastases ◽

Focal Liver Lesions ◽

Imaging Features ◽

Liver Lesions ◽

Gray Scale ◽

Post Contrast ◽

Contrast Enhanced ◽

Before And After

This study compared the imaging features of conventional gray scale ultrasound (US) before and after contrast-enhanced ultrasound (CEUS) for focal liver lesions and 22 evaluated the role of US post-CEUS in characterizing liver lesions. 126 patients with 158 focal liver lesions underwent CEUS and US post-CEUS examination and entered this study. There were 74 hepatocellular carcinomas (HCC), 43 hepatic metastases, and 41 hemangiomas. Imaging features of US pre-CEUS and US post-CEUS were analyzed offsite by two blinded experienced radiologists to evaluate size, boundary, echogenicity, internal texture, posterior acoustic enhancement, spatial resolution, and contrast resolution. In the end with pathological and clinical evidence, the diagnostic accuracy rate of US pre-CEUS was 53.8% (85/158 lesions), lower than that of CEUS (88.0%, 139/158 lesions); with the complementation of US post-CEUS the rate rose to 93.0% (147/158 lesions). US post-CEUS could improve the visibility of typical structures of focal liver lesions and might provide important complementary information for CEUS diagnosis. It also increases the visibility of small liver lesions compared with US pre-CEUS and helps to guide local interventional procedure.

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