An Unusual Presentation of Peripheral Ossifying Fibroma in an Elderly Male - A Case Report

Peripheral ossifying fibroma (POF) is a reactive process of the gingiva that develops due to irritation or minor trauma. Females are more affected than males suggesting a hormonal influence. This case report describes a case of peripheral ossifying fibroma in a 48-year-old male patient in 33, 34 regions in contrast to its common occurrence in young females. Histopathological examination is necessary to confirm the diagnosis. Surgical excision is the treatment of choice to prevent recurrence. One year follow up of the case showed no signs of recurrence. Gingival overgrowth is a common feature of the various types of gingival disease in the oral cavity. Gingival diseases and conditions can be due to genetic disorder, specific infections, inflammatory and immune conditions and lesions, reactive processes, neoplasms, endocrine, nutritional, and metabolic diseases, traumatic lesions and gingival pigmentation.1 Reactive processes are non-neoplastic nodular swellings that develop in response to local irritation or minor trauma. The term epulis is exophytic processes confined to the gingiva.2 Kfir et al. classified epulides into fibrous epulis, peripheral ossifying fibroma, pyogenic granuloma (vascular epulis), peripheral giant cell granuloma (or central).3 Ossifying fibromas in the oral cavity can be classified into central and peripheral type. The central type expands from the medullary cavity of the bone, arising from the endosteum or the periodontal ligament (PDL) adjacent to the root apex. Peripheral type arises from the soft tissues overlying the alveolar process which is contiguous with the periodontal ligament. 4 This article presents a case of POF in a male patient.

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Large peripheral ossifying fibroma interfering with the normal functions of the oral cavity: A rare case report presentation and discussion

International Journal of Surgery Case Reports ◽

10.1016/j.ijscr.2021.106127 ◽

2021 ◽

Vol 84 ◽

pp. 106127

Author(s):

Hamad Nasser Albagieh

Keyword(s):

Case Report ◽

Oral Cavity ◽

Rare Case ◽

Ossifying Fibroma ◽

Normal Functions ◽

Peripheral Ossifying Fibroma ◽

Rare Case Report ◽

Report Presentation

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Atypical Peripheral Ossifying Fibroma of the Mandible

Dentistry Journal ◽

10.3390/dj10010009 ◽

2022 ◽

Vol 10 (1) ◽

pp. 9

Author(s):

Tomislav Katanec ◽

Lea Budak ◽

Davor Brajdić ◽

Dragana Gabrić

Keyword(s):

Oral Mucosa ◽

Male Patient ◽

Periodontal Ligament ◽

Histological Analysis ◽

Histological Diagnosis ◽

Ossifying Fibroma ◽

Lateral Part ◽

Discussion Section ◽

Female Patients ◽

Peripheral Ossifying Fibroma

Peripheral ossifying fibroma (POF) is a benign localized lesion originating from gingival and alveolar oral mucosa. Its origin can be cells of periodontal ligament. The lesions usually develop in women in their twenties. POF is a complex clinical and histological diagnosis due to its shared characteristics with many other conditions. In this paper, we presented a case of an atypical peripheral ossifying fibroma (POF) in the left lateral part of the mandible in a 70-year-old male patient who had two semicircular bridges supported on four implants in the upper and lower jaws. A review of CBCT and orthopedic imaging showed no visible intraosseous changes. Histological analysis revealed the diagnosis of POF. The case in question is interesting, as elaborated on in the discussion section of this paper because POF is usually found in female patients aged between 20 and 30 years.

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Peripheral Ossifying Fibroma: A Case Report

International Journal of Pharma and Bio Sciences ◽

10.22376/ijpbs/lpr.2021.11.3.l38-42 ◽

2021 ◽

Vol 11 (3) ◽

Author(s):

Dr. Romita Dilip Gaikwad ◽

Dr. Farooque Khan

Keyword(s):

Case Report ◽

Oral Cavity ◽

Pyogenic Granuloma ◽

Ossifying Fibroma ◽

Transitional Form ◽

Peripheral Ossifying Fibroma ◽

Clinical Presentations ◽

Separate Clinical Entity ◽

Oral Tumors ◽

Irritation Fibroma

The gingiva is often considered as one of the most common sites of localized growths that are considered to be reactive rather than malignant in nature. Clinically, the majority of these lesions are difficult to identify, and therefore histopathology is useful in diagnosing these lesions as specific entities only on the basis of typical and consistent features. Focal gingival enlargements are quite frequent lesions in the oral cavity amounting to almost 3.1% of all oral tumors and 9.6% of gingival lesions. Peripheral ossifying fibroma (POF) is one of the reactive lesions that have typical histopathological features. Since the late 1940s, intraoral ossifying fibromas have been discussed in the literature. The term “Peripheral ossifying fibroma” is usually used to describe a fibroma of the gingiva which shows areas of calcification or ossification. They are usually classified as non-neoplastic enlargement of the gingiva. Many POFs are thought to develop initially as a pyogenic granuloma that undergoes fibrous maturation and subsequent calcification. However, many authors have suggested that rather than a transitional form of pyogenic granuloma or irritation fibroma, POF represents a separate clinical entity. Different lesions with clinical presentations similar to POF make it difficult to arrive at an appropriate diagnosis. Usually, the treatment of POF includes excision of the lesion surgically with minimal chances of recurrence. This paper describes a case report of a 32 year old female patient who reported growth on gingiva in the mandibular left anterior region of the mouth for three years.

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Laser Excision of Large Peripheral Ossifying Fibroma, Histological and Radiographic Interpretation: A Case Report

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/47156.14503 ◽

2021 ◽

Author(s):

Preeti Karhana ◽

Vidushi Sheokand ◽

Amit Bhardwaj ◽

Neha Munjal

Keyword(s):

Case Report ◽

Oral Cavity ◽

Ossifying Fibroma ◽

Anterior Maxilla ◽

Histological Features ◽

Significant Growth ◽

Peripheral Ossifying Fibroma ◽

Radiographic Interpretation ◽

Laser Excision

In oral cavity, the site for localised growth is usually gingiva which is considered as reactive in nature. Many of these lesions can be identified only on the basis of typical and consistent histomorphology and are difficult to identify clinically. One such reactive lesion which is clinically similar in presentation is Peripheral Ossifying Fibroma (POF). Females are affected more often than males. The presented case report is of a 45-year-old female with a significant growth of large POF in the anterior maxilla. The various clinical, radiological and histological features and diagnosis of POF with its treatment of choice are explained.

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Peripheral Ossifying Fibroma: A Case Report

Journal of Nepalese Society of Periodontology and Oral Implantology ◽

10.3126/jnspoi.v4i1.30903 ◽

2020 ◽

Vol 4 (1) ◽

pp. 39-42

Author(s):

Barun Kumar Sah ◽

Bandana Koirala ◽

Mamta Dali ◽

Sneha Shrestha

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Periodontal Ligament ◽

Ossifying Fibroma ◽

Reactive Process ◽

Peripheral Ossifying Fibroma ◽

Neoplastic Process ◽

One Year

Peripheral ossifying fibroma (POF) is a common solitary gingival growth thought to arise from the periodontal ligament. Though the etiology of POF remains unknown, some investigators consider it an inflammatory or reactive process, while others suggest it is a neoplastic process. Here, we present a case of POF in a 10-year-old boy, affecting the maxillary anterior gingiva along with its clinical, radiographic, histologic characteristics, differential diagnosis, treatment and one year follow-up.

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