Drug Induced Liver Injury Caused by Herbal Male Enhancing products: A Rare Case

2016 ◽  
Vol 111 ◽  
pp. S959-S960
Author(s):  
Rooma Nankani ◽  
Amruta Panwala ◽  
Deepa Nankani ◽  
Ameet Kumar ◽  
Lisa Rossi
2016 ◽  
Vol 111 ◽  
pp. S943
Author(s):  
Mohamed Barakat ◽  
Mostafa Alfishawy ◽  
Saphwat Eskaros ◽  
Ahmed Kawser

Author(s):  
Rajnish Raj ◽  
Nisha Bhagat

Drug Induced Liver Injury (DILI) is one of the leading causes of liver damage worldwide and raises concerns about its prescription in lieu of the limited drug options available for the depression. Venlafaxine (VEN) is an antidepressant with dual neurotransmitter receptor modulations i.e., serotonin and norepinephrine reuptake inhibitor (SNRI) and having an additional benefit in management of vasomotor symptoms especially in menopausal patients where hormone replacement therapy (HRT) is contraindicated. VEN induced hepatotoxicity have been reported to occur in less than 1% of patients. Until now, less than 11 cases of VEN-related liver injuries have been reported in literature. We hereby, report a rare case of VEN induced liver injury in a 40-year-old breast cancer survivor with co-morbid depression.


2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Keith Glenn ◽  
Patrick Chen ◽  
Mustafa Musleh ◽  
Rao Pallivi ◽  
Melissa Grilliot

Importance. As Rivaroxaban has increased in popularity, it has been accompanied with a growing body of evidence displaying its ability to cause drug induced liver injury (DILI). Observation. A 74-year-old Caucasian female developed Rivaroxaban DILI two weeks after finishing a 14-day course. The patient was symptomatic and jaundiced with elevated transaminases and hyperbilirubinemia with normal lab values two months priorly. Liver biopsies showed mixed inflammatory infiltrate of lymphocytes, neutrophils and eosinophils, rare necrotic hepatocytes, and canalicular and intrahepatocellular cholestasis, all of which are consistent with DILI. Conclusion and Relevance. We present this case to add to the growing evidence that Rivaroxaban can be associated with severe, symptomatic liver injury and to ensure physicians are aware of these possible side effects of novel anticoagulants with their increasing use.


2012 ◽  
Vol 107 ◽  
pp. S191
Author(s):  
Siddharth Bansal ◽  
Alexander Mallari ◽  
Radu Serban ◽  
Jason Gutman ◽  
Joel McFarland

2019 ◽  
Vol 14 (3) ◽  
pp. 878 ◽  
Author(s):  
Tomohiro Kawaguchi ◽  
Teiji Tominaga

2020 ◽  
Vol 115 (1) ◽  
pp. S1389-S1389 ◽  
Author(s):  
Navim Mobin ◽  
Arifa Khan ◽  
Smruti Ranjan Mohanty

2019 ◽  
Vol 80 (8) ◽  
pp. 476-477 ◽  
Author(s):  
Erica RM Pool ◽  
Sorina Bolache ◽  
Chris Wood

2020 ◽  
Vol 12 (2) ◽  
pp. 54-58
Author(s):  
St. Nurul ◽  
Reski Wahyuni ◽  
Khairuddin Djawad ◽  
Faridha S Ilyas ◽  
Wiwiek Dewiyanti ◽  
...  

AbstractAcute Generalized Exanthemataous Pustulosis (AGEP) is a rare acute pustular eruption that is mostly induced by drugs. Aside from cutaneous eruptions, systemic symptoms such as leukocytosis, neutrophilia, and internal organ involvement such as liver, kidney, respiratory system, and bone marrow, may occur, although uncommon. Liver involvement usually results in a two- or three-fold increase of liver enzymes and rarely exceeds that. Pyrazinamide is the first-line anti-tuberculosis drug that is potentially hepatotoxic, but rarely shows dermatologic manifestations. We report a rare case of AGEP with drug induced liver injury due to pyrazinamide in a young patient with tuberculosis.


Praxis ◽  
2010 ◽  
Vol 99 (21) ◽  
pp. 1259-1265 ◽  
Author(s):  
Bruggisser ◽  
Terraciano ◽  
Rätz Bravo ◽  
Haschke

Ein 71-jähriger Patient stellt sich mit Epistaxis und ikterischen Skleren auf der Notfallstation vor. Der Patient steht unter einer Therapie mit Phenprocoumon, Atorvastatin und Perindopril. Anamnestisch besteht ein langjähriger Alkoholabusus. Laborchemisch werden massiv erhöhte Leberwerte (ALAT, Bilirubin) gesehen. Der INR ist unter oraler Antikoagulation und bei akuter Leberinsuffizienz >12. Die weiterführenden Abklärungen schliessen eine Virushepatitis und eine Autoimmunhepatitis aus. Nachdem eine Leberbiopsie durchgeführt werden kann, wird eine medikamentös-toxische Hepatitis, ausgelöst durch die Komedikation von Atorvastatin, Phenprocoumon und Perindopril bei durch Alkohol bereits vorgeschädigter Leber diagnostiziert. Epidemiologie, Pathophysiologie und Klink der medikamentös induzierten Leberschäden (drug induced liver injury, DILI), speziell von Coumarinen, Statinen und ACE-Hemmern werden im Anschluss an den Fallbericht diskutiert.


Hepatology ◽  
2004 ◽  
Vol 40 (4) ◽  
pp. 773-773 ◽  
Author(s):  
Jay H. Hoofnagle

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