The Impact of Single-Level Anterior Cervical Discectomy and Fusion on Cervical Sagittal Parameters and Its Correlation With Pain and Functional Outcome of Patients With Neck Pain

Background: Cervical disc disease and spondylosis is a common pathological entity and is characterised by increasing degeneration of the intervertebral disc with subsequent changes in the bones and soft tissues. Aim: To determine functional outcome of anterior cervical discectomy with fusion and plating in single level degenerative cervical disc prolapse. Methods and Materials: This study was done at the Department of Neurosurgery, Medical Trust Hospital, Kochi over a period of three years after receiving institutional ethical clearance. 60 patients aged between 20 to 60 years, both male and female, who had degenerative disc disease with single level herniation with worsening or non-improving neck pain with radiculopathy, corresponding neurologic deficit, who were admitted in our unit were included in the study. Baseline data like name, age and gender were recorded for all the patients included in the study. Clinical examination consisted of history, thorough neurological examination and corresponding radiological evaluation. A visual analogue scale was used to make a subjective assessment of the patient’s complaints (pre-operative and post-operative). Results: A total of 60 patients were included in the present study, among them 40 were males and 20 were females with male to female ratio of 2:1. All of them showed a significantly better improvement in visual analogue scale score of neck pain and UE radicular pain (p<0.05). The post-operative improvements in the clinical presentation of the patients were also noted. Conclusion: A single level of anterior discectomy and cervical fusion for degenerative cervical disc prolapse with and without radiculo-myelopathy is an effective, successful and safe operation with minimal complication rate. The visual analogue scale following surgery was significantly improved.

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Impact of Age and Duration of Symptoms on Surgical Outcome of Single-Level Microscopic Anterior Cervical Discectomy and Fusion in the Patients with Cervical Spondylotic Radiculopathy

Neuroscience Journal ◽

10.1155/2014/808596 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 8

Author(s):

Farzad Omidi-Kashani ◽

Ebrahim Ghayem Hasankhani ◽

Reza Ghandehari

Keyword(s):

Surgical Outcome ◽

Anterior Cervical Discectomy ◽

Symptom Duration ◽

Duration Of Symptoms ◽

Cervical Discectomy ◽

Single Level ◽

Cervical Spondylotic Radiculopathy ◽

Significant Difference ◽

The Impact

We aim to evaluate the impact of age and duration of symptoms on surgical outcome of the patients with cervical spondylotic radiculopathy (CSR) who had been treated by single-level microscopic anterior cervical discectomy and fusion (ACDF). We retrospectively evaluated 68 patients (48 female and 20 male) with a mean age of 41.2±4.3 (ranged from 24 to 72 years old) in our Orthopedic Department, Imam Reza Hospital. They were followed up for 31.25±4.1 months (ranged from 25 to 65 months). Pain and disability were assessed by Visual Analogue Scale (VAS) and Neck Disability Index (NDI) questionnaires in preoperative and last follow-up visits. Functional outcome was eventually evaluated by Odom’s criteria. Surgery could significantly improve pain and disability from preoperative 6.2±1.4 and 22.2±6.2 to 3.5±2.0 and 8.7±5.2 (1–21) at the last follow-up visit, respectively. Satisfactory outcomes were observed in 89.7%. Symptom duration of more and less than six months had no effect on surgical outcome, but the results showed a statistically significant difference in NDI improvement in favor of the patients aged more than 45 years (P=0.032), although pain improvement was similar in the two groups.

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The Impact of Modic-2 changes on the clinical outcomes of single-level anterior cervical discectomy and fusion

European Spine Journal ◽

10.1007/s00586-015-4161-1 ◽

2015 ◽

Vol 24 (12) ◽

pp. 2936-2940 ◽

Cited By ~ 4

Author(s):

Jia Li ◽

Tao Lei ◽

Yong Shen

Keyword(s):

Clinical Outcomes ◽

Anterior Cervical Discectomy ◽

Cervical Discectomy ◽

Single Level ◽

The Impact

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Nonunion Rates After Anterior Cervical Discectomy and Fusion: Comparison of Polyetheretherketone vs Structural Allograft Implants

Neurosurgery ◽

10.1093/neuros/nyab079 ◽

2021 ◽

Author(s):

Won Hyung A Ryu ◽

Dominick Richards ◽

Mena G Kerolus ◽

Adewale A Bakare ◽

Ryan Khanna ◽

...

Keyword(s):

Smoking Status ◽

Posterior Instrumentation ◽

Patient Reported Outcome ◽

Anterior Cervical Discectomy ◽

Successful Outcome ◽

Cervical Discectomy ◽

Structural Allograft ◽

Modifiable Factors ◽

Patient Reported ◽

The Impact

Abstract BACKGROUND Although advances in implant materials, such as polyetheretherketone (PEEK), have been developed aimed to improve outcome after anterior cervical discectomy and fusion (ACDF), it is essential to confirm whether these changes translate into clinically important sustained benefits. OBJECTIVE To compare the radiographic and clinical outcomes of patients undergoing up to 3-level ACDF with PEEK vs structural allograft implants. METHODS In this cohort study, radiographic and symptomatic nonunion rates were compared in consecutive patients who underwent 1 to 3 level ACDF with allograft or PEEK implant. Prospectively collected clinical data and patient-reported outcome (PRO) scores were compared between the allograft and PEEK groups. Regression analysis was performed to determine the predictors of nonunion. RESULTS In total, 194 of 404 patients met the inclusion criteria (79% allograft vs 21% PEEK). Preoperative demographic variables were comparable between the 2 groups except for age. The rate of radiographic nonunion was higher with PEEK implants (39% vs 27%, P = .0035). However, a higher proportion of nonunion in the allograft cohort required posterior instrumentation (14% vs 3%, P = .039). Patients with multilevel procedures and PEEK implants had up to 5.8 times the risk of radiographic nonunion, whereas younger patients, active smokers, and multilevel procedures were at higher risk of symptomatic nonunion. CONCLUSION Along with implant material, factors such as younger age, active smoking status, and the number of operated levels were independent predictors of fusion failure. Given the impact of nonunion on PRO, perioperative optimization of modifiable factors and surgical planning are essential to ensure a successful outcome.

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