Hubungan antara Lingkar Leher dengan Rasio Trigliserida/High-Density Lipoprotein pada Remaja

Etisa Adi Murbawani

doi:10.14710/jnh.6.1.2018.9-16

Hubungan antara Lingkar Leher dengan Rasio Trigliserida/High-Density Lipoprotein pada Remaja

JNH (JOURNAL OF NUTRITION AND HEALTH) ◽

10.14710/jnh.6.1.2018.9-16 ◽

2018 ◽

Vol 6 (1) ◽

pp. 9

Author(s):

Etisa Adi Murbawani

Keyword(s):

High Density Lipoprotein ◽

Density Lipoprotein ◽

High Density

Latar Belakang : Peningkatan kadar trigliserida dan High-Density Lipoprotein erat kaitannya dengan kejadian obesitas, penyakit kardiovaskuler, dan sindrom metabolik. Lingkar leher merupakan salah satu metode pengukuran antropometri yang dapat digunakan untuk melakukan skrining terhadap beberapa indikator biokimia. Penelitian ini bertujuan mengetahui hubungan antara lingkar leher dengan rasio trigliserida / High-Density Lipoprotein pada remaja.Metode : Penelitian ini merupakan penelitian analitik observasional terhadap 28 remaja berusia 12-15 tahun di Semarang. Data lingkar leher diperoleh dengan melakukan pengukuran menggunakan pita ukur melingkar pada bagian tengah leher. Pengambilan darah dan uji laboratorium dilakukan setelah subyek berpuasa 6 – 8 jam. Hubungan antara lingkar leher dan rasio TG/HDL akan dianalisis menggunakan uji korelasi spearman. Uji korelasi spearman juga dilakukan untuk melihat hubungan variabel confounding dengan rasio TG/HDL. Selanjutnya dilakukan uji regresi linear bertingkat untuk mengetahui variabel yang paling berhubungan dengan rasio TG/HDL.Hasil :: Terdapat hubungan positif yang kuat antara lingkar leher dengan rasio TG/HDL (p=0,000, r=0,677). Setelah dilakukan analisis multivariat, lingkar pinggang juga berpengaruh terhadap rasio TG/HDL. Hal ini dapat disebabkan oleh tidak meratanya distirbusi sunyek dalam penelitian ini.Kesimpulan : Rasio TG/HDL dipengaruhi oleh lingkar leher dan lingkar pinggang.Kata Kunci : lingkar leher, rasio trigliserda/HDL, remaja

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Role of Circulating High-Density Lipoprotein and Triglycerides in Coronary Artery Disease: Risk and Prevention

Endocrinology and Metabolism Clinics of North America ◽

10.1016/s0889-8529(18)30326-8 ◽

1990 ◽

Vol 19 (2) ◽

pp. 299-309 ◽

Cited By ~ 10

Author(s):

David J. Gordon

Keyword(s):

Coronary Artery Disease ◽

Coronary Artery ◽

High Density Lipoprotein ◽

Disease Risk ◽

Density Lipoprotein ◽

High Density ◽

Coronary Artery Disease Risk ◽

Artery Disease

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Triglyceride to high density lipoprotein cholesterol ratio, total cholesterol to high density lipoprotein cholesterol ratio and low ankle brachial index in an elderly population

VASA ◽

10.1024/0301-1526/a000348 ◽

2014 ◽

Vol 43 (3) ◽

pp. 189-197 ◽

Cited By ~ 10

Author(s):

Yiqiang Zhan ◽

Jinming Yu ◽

Rongjing Ding ◽

Yihong Sun ◽

Dayi Hu

Keyword(s):

High Density Lipoprotein ◽

Total Cholesterol ◽

High Density Lipoprotein Cholesterol ◽

Ankle Brachial Index ◽

Density Lipoprotein ◽

High Density ◽

Lipoprotein Cholesterol ◽

Lipid Lowering ◽

Cholesterol Ratio ◽

Potential Biomarker

Background: The associations of triglyceride (TG) to high-density lipoprotein cholesterol ratio (HDL‑C) and total cholesterol (TC) to HDL‑C ratio and low ankle brachial index (ABI) were seldom investigated. Patients and methods: A population based cross-sectional survey was conducted and 2982 participants 60 years and over were recruited. TG, TC, HDL‑C, and low-density lipoprotein cholesterol (LDL-C) were assessed in all participants. Low ABI was defined as ABI ≤ 0.9 in either leg. Multiple logistic regression models were applied to study the association between TG/HDL‑C ratio, TC/HDL‑C ratio and low ABI. Results: The TG/HDL‑C ratios for those with ABI > 0.9 and ABI ≤ 0.9 were 1.28 ± 1.20 and 1.48 ± 1.13 (P < 0.0001), while the TC/HDL‑C ratios were 3.96 ± 1.09 and 4.32 ± 1.15 (P < 0.0001), respectively. After adjusting for age, gender, body mass index, obesity, current drinking, physical activity, hypertension, diabetes, lipid-lowering drugs, and cardiovascular disease history, the odds ratios (ORs) with 95 % confidence intervals (CIs) of low ABI for TG/HDL‑C ratio and TC/HDL‑C ratio were 1.10 (0.96, 1.26) and 1.34 (1.14, 1.59) in non-smokers. When TC was further adjusted, the ORs (95 % CIs) were 1.40 (0.79, 2.52) and 1.53 (1.21, 1.93) for TG/HDL‑C ratio and TC/HDL‑C ratio, respectively. Non-linear relationships were detected between TG/HDL‑C ratio and TC/HDL‑C ratio and low ABI in both smokers and non-smokers. Conclusions: TC/HDL‑C ratio was significantly associated with low ABI in non-smokers and the association was independent of TC, TG, HDL‑C, and LDL-C. TC/HDL‑C might be considered as a potential biomarker for early peripheral arterial disease screening.

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