scholarly journals An Investigation of Innovative 3D Modelling Procedures for Patient-specific Total Knee Arthroplasty

2021 ◽  
Vol 19 (2) ◽  
pp. 306-319
Author(s):  
Anna Ghidotti ◽  
Andrea Vitali ◽  
Daniele Regazzoni ◽  
Caterina Rizzi
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
3D Modelling ◽  
Patient Specific ◽  
Total Knee

Total Hospital Costs and Readmission Rate of Patient-Specific Instrument in Total Knee Arthroplasty Patients

2020 ◽  
Author(s):  
Stephen Thomas ◽  
Ankur Patel ◽  
Corey Patrick ◽  
Gary Delhougne
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Hospital Cost ◽  
Readmission Rate ◽  
Hospital Costs ◽  
Patient Specific ◽  
P Value ◽  
Total Hospital Cost ◽  
Total Hospital ◽  
Total Knee

AbstractDespite advancements in surgical technique and component design, implant loosening, stiffness, and instability remain leading causes of total knee arthroplasty (TKA) failure. Patient-specific instruments (PSI) aid in surgical precision and in implant positioning and ultimately reduce readmissions and revisions in TKA. The objective of the study was to evaluate total hospital cost and readmission rate at 30, 60, 90, and 365 days in PSI-guided TKA patients. We retrospectively reviewed patients who underwent a primary TKA for osteoarthritis from the Premier Perspective Database between 2014 and 2017 Q2. TKA with PSI patients were identified using appropriate keywords from billing records and compared against patients without PSI. Patients were excluded if they were < 21 years of age; outpatient hospital discharges; evidence of revision TKA; bilateral TKA in same discharge or different discharges. 1:1 propensity score matching was used to control patients, hospital, and clinical characteristics. Generalized Estimating Equation model with appropriate distribution and link function were used to estimate hospital related cost while logistic regression models were used to estimate 30, 60, and 90 days and 1-year readmission rate. The study matched 3,358 TKAs with PSI with TKA without PSI patients. Mean total hospital costs were statistically significantly (p < 0.0001) lower for TKA with PSI ($14,910; 95% confidence interval [CI]: $14,735–$15,087) than TKA without PSI patients ($16,018; 95% CI: $15,826–$16,212). TKA with PSI patients were 31% (odds ratio [OR]: 0.69; 95% CI: 0.51–0.95; p-value = 0.0218) less likely to be readmitted at 30 days; 35% (OR: 0.65; 95% CI: 0.50–0.86; p-value = 0.0022) less likely to be readmitted at 60 days; 32% (OR: 0.68; 95% CI: 0.53–0.88; p-value = 0.0031) less likely to be readmitted at 90 days; 28% (OR: 0.72; 95% CI: 0.60–0.86; p-value = 0.0004) less likely to be readmitted at 365 days than TKA without PSI patients. Hospitals and health care professionals can use retrospective real-world data to make informed decisions on using PSI to reduce hospital cost and readmission rate, and improve outcomes in TKA patients.

MRI is more accurate than CT for patient-specific total knee arthroplasty

The Knee ◽  
2015 ◽  
Vol 22 (6) ◽  
pp. 609-612 ◽  
Author(s):  
Benjamin M. Frye ◽  
Amjad A. Najim ◽  
Joanne B. Adams ◽  
Keith R. Berend ◽  
Adolph V. Lombardi
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Patient Specific ◽  
Total Knee

Patient-specific instruments for total knee arthroplasty can accurately predict the component size as used peroperative

2016 ◽  
Vol 25 (12) ◽  
pp. 3844-3848 ◽  
Author(s):  
Martijn G. M. Schotanus ◽  
Daphne A. L. Schoenmakers ◽  
Rob Sollie ◽  
Nanne P. Kort
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Patient Specific ◽  
Component Size ◽  
Patient Specific Instruments ◽  
Total Knee

Improved Radiographic Outcomes With Patient-Specific Total Knee Arthroplasty

2014 ◽  
Vol 29 (11) ◽  
pp. 2100-2103 ◽  
Author(s):  
Conrad B. Ivie ◽  
Patrick J. Probst ◽  
Amrit K. Bal ◽  
James T. Stannard ◽  
Brett D. Crist ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Patient Specific ◽  
Radiographic Outcomes ◽  
Total Knee

Identification of biological risk factors for persistent postoperative pain after total knee arthroplasty

2021 ◽  
pp. rapm-2021-102953
Author(s):  
Alexandra Sideris ◽  
Michael-Alexander Malahias ◽  
George Birch ◽  
Haoyan Zhong ◽  
Valeria Rotundo ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Postoperative Pain ◽  
Synovial Fluid ◽  
Knee Arthroplasty ◽  
Persistent Pain ◽  
Patient Specific ◽  
Multiple Time ◽  
Cytokine Levels ◽  
Total Knee ◽  
Persistent Postoperative Pain

BackgroundThere is growing evidence that cytokines and adipokines are associated with osteoarthritis (OA) severity, progression, and severity of associated pain. However, the cytokine response to total knee arthroplasty (TKA) and its association with persistent postoperative pain is not well understood. This study aims to describe the perioperative systemic (plasma) and local (synovial fluid) cytokine profiles of patients who do and do not develop persistent pain after TKA.MethodsPatients undergoing primary unilateral TKA for end-stage OA were prospectively enrolled. Demographic and clinical data were gathered preoperatively and postoperatively. Synovial fluid was collected pre arthrotomy and plasma was collected at multiple time points before and after surgery. Persistent postoperative pain (PPP) was defined as Numerical Rating Score≥4 at 6 months. Cytokine levels were measured using the V-Plex Human Cytokine 30-Plex Panel (Mesoscale—Rockville, Maryland, USA). Cytokine levels were compared between PPP and minimal pain groups. Given that the study outcomes are exploratory, no adjustment was performed for multiple testing.ResultsIncidence of persistent pain at 6 months post TKA was 15/162 (9.3%). Postoperative plasma levels of four cytokines were significantly different in patients who developed persistent postoperative pain: interleukin (IL)-10, IL-1β, vascular endothelial growth factor, and IL12/IL23p40. Significantly lower IL-10 levels in the prearthrotomy synovial fluid were associated with development of postoperative persistent pain.ConclusionsThis prospective cohort study described a distinct acute perioperative inflammatory response profile in patients who developed persistent post-TKA pain, characterized by significant differences in four cytokines over the first 2 postoperative days. These results support the growing evidence that the patient-specific biologic response to surgery may influence longer-term clinical outcomes after TKA.Trial registration numberClinicaltrials.gov NCT02626533.

scholarly journals 3D Modelling of the Knee Driven by Total Knee Arthroplasty Strategies

2021 ◽  
Author(s):  
Anna Ghidotti ◽  
Andrea Vitali ◽  
Daniele Regazzoni ◽  
Caterina Rizzi
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
3D Modelling ◽  
Total Knee
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