Effectiveness of Varicella Zoster Immune Globulin Administration within 96 Hours versus more than 96 Hours after Exposure to the Varicella-Zoster Virus

2015 ◽  
Vol 22 (2) ◽  
pp. 55
Author(s):  
Sun-Ja Kim ◽  
Byung-Kee Lee ◽  
Yang-Hyun Kim ◽  
Soo-Jin Kim ◽  
Yae-Jean Kim
Keyword(s):  
Varicella Zoster Virus ◽  
Immune Globulin ◽  
Varicella Zoster

Case 3

2020 ◽  
pp. 14-18
Author(s):  
Andrew Woodhouse
Keyword(s):  
Varicella Zoster Virus ◽  
Immune Globulin ◽  
Passive Immunization ◽  
Evidence Base ◽  
Drug Levels ◽  
Varicella Zoster ◽  
Intravenous Treatment ◽  
Varicella Pneumonia

Chickenpox is caused by varicella-zoster virus and is predominantly a self-limiting disease of childhood. Chickenpox in adults is more likely to be associated with complications such as varicella pneumonia. Treatment with antivirals is helpful in adults if given early after the onset of rash in uncomplicated disease. In complicated disease such as pneumonia, intravenous treatment is essential to optimize drug levels although an evidence base for this is lacking. Exposure to varicella during pregnancy is a particular concern for non-immune women and passive immunization with varicella immune globulin is indicated.

Varicella zoster virus antibody titers after intravenous zoster immune globulin in neonates, and the safety of this preparation

2005 ◽  
Vol 94 (6) ◽  
pp. 790-793 ◽  
Author(s):  
Teresa Murguía-de-Sierra ◽  
Mónica Villa-Guillén ◽  
Dina Villanueva-García ◽  
Antide Molina ◽  
Alejandra Juárez-Chávez ◽  
...  
Keyword(s):  
Varicella Zoster Virus ◽  
Immune Globulin ◽  
Virus Antibody ◽  
Varicella Zoster ◽  
Antibody Titers

Varicella zoster virus antibody titers after intravenous zoster immune globulin in neonates, and the safety of this preparation

2007 ◽  
Vol 94 (6) ◽  
pp. 790-793 ◽  
Author(s):  
Teresa Murguía-de-Sierra ◽  
Mónica Villa-Guillén ◽  
Dina Villanueva-García ◽  
Antide Molina ◽  
Alejandra Juárez-Chávez ◽  
...  
Keyword(s):  
Varicella Zoster Virus ◽  
Immune Globulin ◽  
Virus Antibody ◽  
Varicella Zoster ◽  
Antibody Titers

Letter To The Editor

PEDIATRICS ◽  
1979 ◽  
Vol 63 (2) ◽  
pp. 348-348
Author(s):  
C. Henry Kempe ◽  
Anne A. Gershon
Keyword(s):  
High Risk ◽  
Varicella Zoster Virus ◽  
No Value ◽  
Immune Globulin ◽  
Passive Immunization ◽  
Practical Method ◽  
Active Immunization ◽  
Varicella Zoster ◽  
Hyperimmune Globulin ◽  
High Risk Children

The studies of Zaia et al demonstrating a practical method for preparation of hyperimmune globulin, varicella-zoster immune globulin (VZIG), for passive immunization against varicella are encouraging. Consequently, in the future, it should be possible to obtain VZIG for high-risk children who have known exposures to varicella-zoster virus. However, we believe that history has demonstrated that passive immunization is rarely a substitute for active immunization, and varicella is no exception to this rule. Passive immunization will be of no value if (1) persons are unaware that they were exposed or (2) they wait too long after exposure before notifying their physician.

Varicella Vaccine

PEDIATRICS ◽  
1979 ◽  
Vol 63 (2) ◽  
pp. 348-348
Author(s):  
John A. Zaia ◽  
Myron J. Levin
Keyword(s):  
Varicella Zoster Virus ◽  
Immune Globulin ◽  
Varicella Vaccine ◽  
Normal Blood ◽  
Foreseeable Future ◽  
Varicella Zoster

Kempe and Gershon in a commentary on the varicella vaccine (Pediatrics 60:930, December 1977) enumerate the factors that might influence the development of such a vaccine. They state that zoster immune globulin (ZIG), which can modify chickenpox in susceptible immunosuppressed children exposed to the varicella-zoster virus, is often not available. However, we wish to point out that varicella-zoster immune globulin (VZIG) has now been prepared from selected outdated normal blood in quantities that could meet the needs of these children in the foreseeable future.1

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